HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
1. 1) A nurse is caring for a client 3. Calcitonin (Miacalcin)
with hyperparathyroidism and Rationale:
notes that the client's serum cal- The normal serum calcium level is 8.6 to 10.0 mg/dL. This
cium level is 13 mg/dL. Which client is experiencing hypercalcemia. Calcium gluconate
medication should the nurse and calcium chloride are medications used for the treat-
prepare to administer as pre- ment of tetany, which occurs as a result of acute hypocal-
scribed to the client? cemia. In hypercalcemia, large doses of vitamin D need
1. Calcium chloride to be avoided. Calcitonin, a thyroid hormone, decreases
2. Calcium gluconate the plasma calcium level by inhibiting bone resorption and
3. Calcitonin (Miacalcin) lowering the serum calcium concentration.
4. Large doses of vitamin D
2. 2.) Oral iron supplements are 4. Orange juice
prescribed for a 6-year-old child Rationale:
with iron deficiency anemia. The Vitamin C increases the absorption of iron by the body. The
nurse instructs the mother to mother should be instructed to administer the medication
administer the iron with which with a citrus fruit or a juice that is high in vitamin C. Milk
best food item? may affect absorption of the iron. Water will not assist in
1. Milk absorption. Orange juice contains a greater amount of vit-
2. Water amin C than apple juice.
3. Apple juice
4. Orange juice
3. 3.) Salicylic acid is prescribed 1. Tinnitus
for a client with a diagnosis of Rationale:
psoriasis. The nurse monitors Salicylic acid is absorbed readily through the skin, and
the client, knowing that which systemic toxicity (salicylism) can result. Symptoms include
of the following would indicate tinnitus, dizziness, hyperpnea, and psychological distur-
the presence of systemic toxici- bances. Constipation and diarrhea are not associated with
ty from this medication? salicylism.
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
1. Tinnitus
2. Diarrhea
3. Constipation
4. Decreased respirations
4. 4.) The camp nurse asks the 4. At least 30 minutes before exposure to the sun
children preparing to swim in Rationale:
the lake if they have applied Sunscreens are most effective when applied at least 30 min-
sunscreen. The nurse reminds utes before exposure to the sun so that they can penetrate
the children that chemical sun- the skin. All sunscreens should be reapplied after swimming
screens are most effective when or sweating.
applied:
1. Immediately before swim-
ming
2. 15 minutes before exposure
to the sun
3. Immediately before expo-
sure to the sun
4. At least 30 minutes before
exposure to the sun
5. 5.) Mafenide acetate (Sulfamy- 3. Informing the client that this is normal
lon) is prescribed for the client Rationale:
with a burn injury. When apply- Mafenide acetate is bacteriostatic for gram-negative and
ing the medication, the client gram-positive organisms and is used to treat burns to re-
complains of local discomfort duce bacteria present in avascular tissues. The client should
and burning. Which of the fol- be informed that the medication will cause local discomfort
lowing is the most appropriate and burning and that this is a normal reaction; therefore
nursing action? options 1, 2, and 4 are incorrect
1. Notifying the registered
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
nurse
2. Discontinuing the medica-
tion
3. Informing the client that this
is normal
4. Applying a thinner film than
prescribed to the burn site
6. 6.) The burn client is receiving 1.Hyperventilation
treatments of topical mafenide Rationale:
acetate (Sulfamylon) to the site Mafenide acetate is a carbonic anhydrase inhibitor and can
of injury. The nurse monitors suppress renal excretion of acid, thereby causing acidosis.
the client, knowing that which Clients receiving this treatment should be monitored for
of the following indicates that a signs of an acid-base imbalance (hyperventilation). If this
systemic effect has occurred? occurs, the medication should be discontinued for 1 to 2
1.Hyperventilation days. Options 3 and 4 describe local rather than systemic
2.Elevated blood pressure effects. An elevated blood pressure may be expected from
3.Local pain at the burn site the pain that occurs with a burn injury.
4.Local rash at the burn site
7. 7.) Isotretinoin is prescribed for 2. Triglyceride level
a client with severe acne. Before Rationale:
the administration of this med- Isotretinoin can elevate triglyceride levels. Blood triglyc-
ication, the nurse anticipates eride levels should be measured before treatment and pe-
that which laboratory test will riodically thereafter until the effect on the triglycerides has
be prescribed? been evaluated. Options 1, 3, and 4 do not need to be
1. Platelet count monitored specifically during this treatment.
2. Triglyceride level
3. Complete blood count
4. White blood cell count
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
8. 8.) A client with severe acne is 1. Vitamin A
seen in the clinic and the health Rationale:
care provider (HCP) prescribes Isotretinoin is a metabolite of vitamin A and can produce
isotretinoin. The nurse reviews generalized intensification of isotretinoin toxicity. Because
the client's medication record of the potential for increased toxicity, vitamin A supplements
and would contact the (HCP) if should be discontinued before isotretinoin therapy. Op-
the client is taking which med- tions 2, 3, and 4 are not contraindicated with the use of
ication? isotretinoin.
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin)
9. 9.) The nurse is applying a top- 2. Axilla
ical corticosteroid to a client Rationale:
with eczema. The nurse would Topical corticosteroids can be absorbed into the systemic
monitor for the potential for circulation. Absorption is higher from regions where the
increased systemic absorption skin is especially permeable (scalp, axilla, face, eyelids,
of the medication if the med- neck, perineum, genitalia), and lower from regions in which
ication were being applied to permeability is poor (back, palms, soles).
which of the following body ar-
eas?
1. Back
2. Axilla
3. Soles of the feet
4. Palms of the hands
10. 10.) The clinic nurse is perform- 1. Acne
ing an admission assessment Rationale:
on a client. The nurse notes that Azelaic acid is a topical medication used to treat mild to
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
1. 1) A nurse is caring for a client 3. Calcitonin (Miacalcin)
with hyperparathyroidism and Rationale:
notes that the client's serum cal- The normal serum calcium level is 8.6 to 10.0 mg/dL. This
cium level is 13 mg/dL. Which client is experiencing hypercalcemia. Calcium gluconate
medication should the nurse and calcium chloride are medications used for the treat-
prepare to administer as pre- ment of tetany, which occurs as a result of acute hypocal-
scribed to the client? cemia. In hypercalcemia, large doses of vitamin D need
1. Calcium chloride to be avoided. Calcitonin, a thyroid hormone, decreases
2. Calcium gluconate the plasma calcium level by inhibiting bone resorption and
3. Calcitonin (Miacalcin) lowering the serum calcium concentration.
4. Large doses of vitamin D
2. 2.) Oral iron supplements are 4. Orange juice
prescribed for a 6-year-old child Rationale:
with iron deficiency anemia. The Vitamin C increases the absorption of iron by the body. The
nurse instructs the mother to mother should be instructed to administer the medication
administer the iron with which with a citrus fruit or a juice that is high in vitamin C. Milk
best food item? may affect absorption of the iron. Water will not assist in
1. Milk absorption. Orange juice contains a greater amount of vit-
2. Water amin C than apple juice.
3. Apple juice
4. Orange juice
3. 3.) Salicylic acid is prescribed 1. Tinnitus
for a client with a diagnosis of Rationale:
psoriasis. The nurse monitors Salicylic acid is absorbed readily through the skin, and
the client, knowing that which systemic toxicity (salicylism) can result. Symptoms include
of the following would indicate tinnitus, dizziness, hyperpnea, and psychological distur-
the presence of systemic toxici- bances. Constipation and diarrhea are not associated with
ty from this medication? salicylism.
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
1. Tinnitus
2. Diarrhea
3. Constipation
4. Decreased respirations
4. 4.) The camp nurse asks the 4. At least 30 minutes before exposure to the sun
children preparing to swim in Rationale:
the lake if they have applied Sunscreens are most effective when applied at least 30 min-
sunscreen. The nurse reminds utes before exposure to the sun so that they can penetrate
the children that chemical sun- the skin. All sunscreens should be reapplied after swimming
screens are most effective when or sweating.
applied:
1. Immediately before swim-
ming
2. 15 minutes before exposure
to the sun
3. Immediately before expo-
sure to the sun
4. At least 30 minutes before
exposure to the sun
5. 5.) Mafenide acetate (Sulfamy- 3. Informing the client that this is normal
lon) is prescribed for the client Rationale:
with a burn injury. When apply- Mafenide acetate is bacteriostatic for gram-negative and
ing the medication, the client gram-positive organisms and is used to treat burns to re-
complains of local discomfort duce bacteria present in avascular tissues. The client should
and burning. Which of the fol- be informed that the medication will cause local discomfort
lowing is the most appropriate and burning and that this is a normal reaction; therefore
nursing action? options 1, 2, and 4 are incorrect
1. Notifying the registered
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
nurse
2. Discontinuing the medica-
tion
3. Informing the client that this
is normal
4. Applying a thinner film than
prescribed to the burn site
6. 6.) The burn client is receiving 1.Hyperventilation
treatments of topical mafenide Rationale:
acetate (Sulfamylon) to the site Mafenide acetate is a carbonic anhydrase inhibitor and can
of injury. The nurse monitors suppress renal excretion of acid, thereby causing acidosis.
the client, knowing that which Clients receiving this treatment should be monitored for
of the following indicates that a signs of an acid-base imbalance (hyperventilation). If this
systemic effect has occurred? occurs, the medication should be discontinued for 1 to 2
1.Hyperventilation days. Options 3 and 4 describe local rather than systemic
2.Elevated blood pressure effects. An elevated blood pressure may be expected from
3.Local pain at the burn site the pain that occurs with a burn injury.
4.Local rash at the burn site
7. 7.) Isotretinoin is prescribed for 2. Triglyceride level
a client with severe acne. Before Rationale:
the administration of this med- Isotretinoin can elevate triglyceride levels. Blood triglyc-
ication, the nurse anticipates eride levels should be measured before treatment and pe-
that which laboratory test will riodically thereafter until the effect on the triglycerides has
be prescribed? been evaluated. Options 1, 3, and 4 do not need to be
1. Platelet count monitored specifically during this treatment.
2. Triglyceride level
3. Complete blood count
4. White blood cell count
, HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUA
EXAM COMPLETE 300 QUESTIONS WITH DETAILED VERIFIED ANSWERS A
RATIONALES (100% CORRECT ANSWERS) /ALREADY GRADED A+
Study online at https://quizlet.com/_grxb5i
8. 8.) A client with severe acne is 1. Vitamin A
seen in the clinic and the health Rationale:
care provider (HCP) prescribes Isotretinoin is a metabolite of vitamin A and can produce
isotretinoin. The nurse reviews generalized intensification of isotretinoin toxicity. Because
the client's medication record of the potential for increased toxicity, vitamin A supplements
and would contact the (HCP) if should be discontinued before isotretinoin therapy. Op-
the client is taking which med- tions 2, 3, and 4 are not contraindicated with the use of
ication? isotretinoin.
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin)
9. 9.) The nurse is applying a top- 2. Axilla
ical corticosteroid to a client Rationale:
with eczema. The nurse would Topical corticosteroids can be absorbed into the systemic
monitor for the potential for circulation. Absorption is higher from regions where the
increased systemic absorption skin is especially permeable (scalp, axilla, face, eyelids,
of the medication if the med- neck, perineum, genitalia), and lower from regions in which
ication were being applied to permeability is poor (back, palms, soles).
which of the following body ar-
eas?
1. Back
2. Axilla
3. Soles of the feet
4. Palms of the hands
10. 10.) The clinic nurse is perform- 1. Acne
ing an admission assessment Rationale:
on a client. The nurse notes that Azelaic acid is a topical medication used to treat mild to
