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NCLEX-RN Pharmacology Review 2025–2026 | Complete Nursing Drug Guide + NCLEX-Style Questions & Rationales (A+ PDF)

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RN NCLEX Pharmacology Comprehensive Review (2025–2026) | Drug Classifications, Med Admin, NCLEX-Style Q&A, and Rationales Master pharmacology for the NCLEX-RN with this comprehensive review guide, specifically designed for nursing students preparing for the 2025–2026 exam cycle. This high-quality resource focuses on the most tested pharmacological topics including drug classifications, mechanisms of action, side effects, contraindications, nursing interventions, and safe medication administration. Ideal for both first-time test takers and repeaters looking to boost their scores. This guide includes NCLEX-style questions with rationales, dosage calculation practice, and critical thinking scenarios to help reinforce clinical judgment. Whether you're studying antibiotics, cardiovascular meds, psychotropics, or insulin protocols — it’s all here. Covers all essential pharmacology topics for NCLEX-RN NCLEX-style multiple-choice + alternate format questions Rationales included for deeper understanding 2025–2026 edition – updated with current drug safety info Printable and searchable PDF format Ideal for RN students, LPN-to-RN bridge, and international nurses Level up your pharmacology game and pass the NCLEX with confidence. HealthStudyPro brings you proven, trusted resources – always A+ read

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RN NCLEX Comprehensive Review: Pharmacology in Nursing
Study online at https://quizlet.com/_7tn6j4

1. 1 mg = ? mcg 1,000 mcg

2. 1 g = ? mg 1,000 mg

3. 1 kg = ? lbs 2.2 lbs

4. 1 gr = ? mg 60 mg

5. 1 oz = ? mL 30 mL

6. 1 L = ? mL 1,000 mL

7. 1 tsp = ? mL 5 mL

8. 1 tbsp = ? mL 15 mL

9. 1 tbsp = ? tsp 3 tsp

10. 37.0 degrees Celsius = ? 98.6 degrees Fahrenheit
degrees Fahrenheit

11. Formula to find Celsius C=(F-32)x(5/9)

12. Formula to find Fahren- F=(Cx9/5)+32
heit

13. Adverse Reaction Negative effects experienced by a client as a result of a specific med-
ication; may be hazardous, tolerated, or subside with continued use

14. RN must assess be- 1. Allergies and adverse effects
fore administering med- 2. Current medication regimen for potential interactions
ications to a pt. (3) 3. Physiologic status compared to baseline assessment data

15. 6 Rights of Medication 1. Right client
Administration 2. Right medication


, RN NCLEX Comprehensive Review: Pharmacology in Nursing
Study online at https://quizlet.com/_7tn6j4

3. Right dose
4. Right time
5. Right route
6. Right documentation

16. Average time to draw 1-2 hours after administration
peak levels: Oral (PO)

17. Average time to draw 1 hour after administration
peak levels: Intramuscu-
lar (IM)

18. Average time to draw 30 minutes
peak levels: Intravenous
(IV)

19. Trough Level Reflect the lowest concentration or residual level and are usually ob-
tained within 15 minutes prior to administration of the next scheduled
dose

20. Culture and Sensitivity Cultures are obtained to detect the presence of pathogens within the
specimen collected. If a culture produces organisms, testing is per-
formed in the laboratory to identify the appropriate antibiotic therapy.
Begin antibiotic therapy after obtaining lab sample.

21. Guidelines for Safe IV 1. Review medication guidelines for precautions related to IV admin-
Administration (5) istration for compatibility, rate of admin., necessity of infusion pump,
and serious adverse reactions
2. Never administer medications through tubing being used for blood
administration
3. Implement standard precautions when performing and IV site
change
4. Fluids should be infused within 24 hours to prevent infection (dis-


, RN NCLEX Comprehensive Review: Pharmacology in Nursing
Study online at https://quizlet.com/_7tn6j4

card unused portion)
5. Maintain patency of IV access

22. Prevent Infiltration of IV 1. Use smallest catheter for prescribed therapy
site (3) 2. Stabilize port-access
3. Assess blood return

23. Treatment for Infiltrated 1. Stop infusion
IV (5) 2. Remove peripheral catheters
3. Apply cold compress
4. Elevate extremity
5. Insert new catheter into opposite extremity

24. Prevent Extravasation of 1. Know vesicant potential before giving med.
IV (1)

25. Treatment for Ex- 1. Stop infusion
travasated IV (5) 2. Discontinue administration set
3. Aspirate drug if possible
4. Apply cold compress
5. Document condition of site (may photograph)

26. Infiltration When IV fluid or medication leaks into surrounding tissue

27. Extravasation Leakage of IV fluid or medication into the extravascular tissue around
the site of infusion

28. Phlebitis/Throm- Inflammatory process that causes a blood clot to form able block one
bophlebitis or more vein

29. Prevent 1. Rotate site every 72h-96h
Phlebitis/Throm- 2. Secure catheter
bophlebitis (3) 3. Use aseptic technique



, RN NCLEX Comprehensive Review: Pharmacology in Nursing
Study online at https://quizlet.com/_7tn6j4

30. Treatment for 1. Stop infusion
Phlebitis/Throm- 2. Remove peripheral catheters
bophlebitis at IV site (4) 3. Apply heat compress
4. Insert new catheter in opposite extremity

31. Hematoma Localized bleeding outside of blood vessels

32. Prevent Hematoma at IV 1. Avoid veins not easily seen or palpated
site (2) 2. Obtain hemostasis after insertion

33. Treatment for 1. Remove IV device
Hematoma at IV site (3) 2. Apply light pressure if bleeding
3. Monitor for signs of phlebitis

34. Prevention of IV 1. Do not reinsert stylet needle into catheter
Catheter Embolus (1)

35. Treatment of IV Catheter 1. Immediately apply tourniquet high on extremity to limit venous flow
Embolus (2) 2. Prepare for removal under X-ray

36. Treatment of Air Em- 1. Place client in left lateral Trendelenburg position
bolism in Central Venous 2. Administer oxygen
Catheter (2)

37. Treatment of Lumen Oc- Use 10mL syringe with a pulsing motion
clusion in Central Ve-
nous Catheter

38. Treatment of Blood- 1. Change entire infusion system
stream Infection in Cen- 2. Notify provider
tral Venous Catheter (4) 3. Obtain cultures
4. Administer antibiotics

39.

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