1
N5315 - ADVANCED PATHOPHYSIOLOGY -
CARDIOMYOPATHIES AND HEART FAILURE NEWLY
FORMATTED STUDY GUIDE WITH ACTUAL 2025/26 EXAM
Tend to result from Cardiomyopathies tend to result from what?
the
neurohormonal
responses to
ischemic heart
disease or
hypertension
Infectious disease, What are other causes of cardiomyopathies?
toxins, systemic
connective tissue
disorders,
nutritional
deficiencies, and
infiltrative
disorders
Affect the What do the pathological
myocardium layer consequences of cardiomyopathies
of the heart affect?
impairing
contractility or
restricting blood
flow
through the heart
,2
3 How many types of cardiomyopathies are
there?
Dilated (DCM); What are the 3 types of cardiomyopathies?
Hypertrophic (HCM);
Restrictive
Dilated (DCM) Which cardiomyopathy is
characterized by a dilated left
ventricle?
A worn out ballon; What can you compare Dilated (DCM)
a balloon which cardiomyopathy to?
has become over
stretched and can
no longer hold its
normal shape
Unable to contract What is a dilated ventricle unable to do?
sufficiently
Volume overload What do people with DCM have difficulty
and pulmonary with?
edema
Fatigue, dyspnea, What are the clinical manifestations of DCM?
S3 heart sound
Ischemia secondary DCM is most often caused by what?
to MI
, 3
Valvular heart What are some other causes of DCM?
disease, diabetes,
renal failure,
hyperthyroidism,
alcohol use (thiamine
deficiency which
decreases ATP
production), cocaine
use, peripartum
complications,
genetic disorders,
infection such as
Coxsackle B virus,
hemochromatosis,
and doxorubicin
toxicity
Hypertrophic (HCM) What is the most common cause of
cardiomyopathy sudden death in young adults?
A familial, What is the most common HCM?
autosomal dominant
disorder; most
commonly
associated with
gene defects on
chromosome 11
Hypertrophy of the What are the pathologic characteristics of
interventricular HCM?
septum and to a
lesser extent the
N5315 - ADVANCED PATHOPHYSIOLOGY -
CARDIOMYOPATHIES AND HEART FAILURE NEWLY
FORMATTED STUDY GUIDE WITH ACTUAL 2025/26 EXAM
Tend to result from Cardiomyopathies tend to result from what?
the
neurohormonal
responses to
ischemic heart
disease or
hypertension
Infectious disease, What are other causes of cardiomyopathies?
toxins, systemic
connective tissue
disorders,
nutritional
deficiencies, and
infiltrative
disorders
Affect the What do the pathological
myocardium layer consequences of cardiomyopathies
of the heart affect?
impairing
contractility or
restricting blood
flow
through the heart
,2
3 How many types of cardiomyopathies are
there?
Dilated (DCM); What are the 3 types of cardiomyopathies?
Hypertrophic (HCM);
Restrictive
Dilated (DCM) Which cardiomyopathy is
characterized by a dilated left
ventricle?
A worn out ballon; What can you compare Dilated (DCM)
a balloon which cardiomyopathy to?
has become over
stretched and can
no longer hold its
normal shape
Unable to contract What is a dilated ventricle unable to do?
sufficiently
Volume overload What do people with DCM have difficulty
and pulmonary with?
edema
Fatigue, dyspnea, What are the clinical manifestations of DCM?
S3 heart sound
Ischemia secondary DCM is most often caused by what?
to MI
, 3
Valvular heart What are some other causes of DCM?
disease, diabetes,
renal failure,
hyperthyroidism,
alcohol use (thiamine
deficiency which
decreases ATP
production), cocaine
use, peripartum
complications,
genetic disorders,
infection such as
Coxsackle B virus,
hemochromatosis,
and doxorubicin
toxicity
Hypertrophic (HCM) What is the most common cause of
cardiomyopathy sudden death in young adults?
A familial, What is the most common HCM?
autosomal dominant
disorder; most
commonly
associated with
gene defects on
chromosome 11
Hypertrophy of the What are the pathologic characteristics of
interventricular HCM?
septum and to a
lesser extent the
