TEST BANK For Abrams’ Clinical Drug Therapy
Rationales for Nursing Practice 12th Edition Geralyn
Frandsen, Verified Chapters 1 - 16, Complete Newest
Version Abrams’ Clinical Drug Therapy Rationales for
Nursing Practice 12th Edition TEST BANK by Geralyn Fr
1.1 The nurse is caring for a woman who has strong beliefs about not putting
anything unnatural into her body. It is most accurate to say that most modern
medications are
A. natural products derived from plants
B. natural products derived from minerals
C. synthetic products manufactured in laboratories
D. synthetic modifications of natural products - answer-C.
Rationale: Although most older drugs originated as plants, minerals, or other
natural products, newer drugs are mainly synthetic. Synthetic drugs are
standardized and therefore more consistent in their characteristics and effects
than natural products.
1.2 The nurse is taking care of a man who is confused about the different
medications he is prescribed. He notes that some of the drug names have
changed over the course of time he has been taking them. When counseling
him, it is most important to keep the following statement in mind:
A. A drug can belong to only one group or classification.
B. A prototype drug is the standard by which similar drugs are compared.
,C. Drug groups and prototypes change frequently, and knowledge about a
prototype cannot guide knowledge about other drugs in the same class.
D. The generic name of a drug changes among manufacturers. - answer-B.
Rationale: The first drug to be developed in a group is usually considered the
prototype or main example of the group, and similar drugs that are developed
later are compared to the prototype. Knowledge of the prototype drug can
help the nurse understand the actions of other drugs in the class. Most drugs
can belong to multiple groups (e.g., a therapeutic group, a chemical group),
depending on various characteristics. Drug groups and prototypes are usually
quite stable, and most new drugs fit into a known classification. The trade or
brand name changes among manufacturers, but the generic name stays the
same.
3.5 Which of the following nursing actions will prevent adverse drug events?
A. Use only the trade name when documenting medications.
B. Crush long-acting medications if the patient has dysphagia.
C. After receiving a verbal order, administer the medication and then write
down the order.
D. Use bar code technology according to institutional policy. - answer-D.
Rationale: Using bar code technology in the administration of medications will
decrease medication administration errors.
2.1 A nurse practitioner (NP) has just changed a patient's medication from an
oral form to a patch formulation to avoid the first-pass effect. The NP has
explained it to the patient, but the patient still has questions and asks the
nurse to explain again what is meant by the first-pass effect. The nurse would
be most correct in explaining that this has to do with how
,A. drugs initially bind to plasma proteins
B. initial renal function is involved in drug excretion
C. the way drugs first reach their target cells
D. initial metabolism of an oral drug occurs before it reaches the systemic
circulation - answer-D.
Rationale: The "first-pass effect" involves metabolism of an oral drug in the
liver so that only a portion of a drug dose reaches the systemic circulation and
becomes available to act on target tissues or to be eliminated from the body.
Drug binding to plasma proteins affects drug distribution; an increased amount
of drug has to be absorbed before effective therapeutic levels of unbound drug
are reached.
2.2 A nurse is reading a research report about use of a medication that
describes the pharmacokinetics of a particular medication that a patient is
taking. Pharmacokinetics involves
A. drug effects on human cells
B. drug binding with receptors
C. drug absorption, distribution, metabolism, and elimination
D. drug stimulation of normal cell functions - answer-C.
Rationale: Pharmacokinetics involves movement of a drug through the body
and its elimination. Drug binding with receptors and drug effects on cells are
pharmacodynamic processes. Drug stimulation of normal cell functions
describes an agonist drug.
2.3 A nurse is caring for a man who has worsening liver disease. In monitoring
his medication, it is important to know that a patient with liver disease may
have impaired drug
A. absorption
, B. distribution
C. metabolism
D. excretion - answer-C.
Rationale: The liver is mainly involved in drug metabolism. The gastrointestinal
tract is mainly involved in absorption of oral drugs, the cardiovascular system is
concerned with distribution, and the kidneys are concerned with excretion.
2.4 A nurse is looking up information about the effects of a drug on different
receptors. Characteristics of receptors include which of the following?
A. They are carbohydrates located in cell membranes or inside cells.
B. They are constantly synthesized and degraded in the body.
C. They bind with molecules of any drug circulating in the bloodstream.
D. They regulate the actions of all drugs. - answer-D.
Rationale: Receptors are mainly proteins that are manufactured and
eliminated like other proteins in the body. Their numbers and binding
capacities can be increased or decreased in particular situations. Most
receptors bind with relatively few drugs. Some drugs do not require receptor
binding for their actions (e.g., antacids such as TUMS or Mylanta).
3.6 A nurse is administering an elixir. Which of the following measures is
appropriate?
A. microgram
B. milligram
Rationales for Nursing Practice 12th Edition Geralyn
Frandsen, Verified Chapters 1 - 16, Complete Newest
Version Abrams’ Clinical Drug Therapy Rationales for
Nursing Practice 12th Edition TEST BANK by Geralyn Fr
1.1 The nurse is caring for a woman who has strong beliefs about not putting
anything unnatural into her body. It is most accurate to say that most modern
medications are
A. natural products derived from plants
B. natural products derived from minerals
C. synthetic products manufactured in laboratories
D. synthetic modifications of natural products - answer-C.
Rationale: Although most older drugs originated as plants, minerals, or other
natural products, newer drugs are mainly synthetic. Synthetic drugs are
standardized and therefore more consistent in their characteristics and effects
than natural products.
1.2 The nurse is taking care of a man who is confused about the different
medications he is prescribed. He notes that some of the drug names have
changed over the course of time he has been taking them. When counseling
him, it is most important to keep the following statement in mind:
A. A drug can belong to only one group or classification.
B. A prototype drug is the standard by which similar drugs are compared.
,C. Drug groups and prototypes change frequently, and knowledge about a
prototype cannot guide knowledge about other drugs in the same class.
D. The generic name of a drug changes among manufacturers. - answer-B.
Rationale: The first drug to be developed in a group is usually considered the
prototype or main example of the group, and similar drugs that are developed
later are compared to the prototype. Knowledge of the prototype drug can
help the nurse understand the actions of other drugs in the class. Most drugs
can belong to multiple groups (e.g., a therapeutic group, a chemical group),
depending on various characteristics. Drug groups and prototypes are usually
quite stable, and most new drugs fit into a known classification. The trade or
brand name changes among manufacturers, but the generic name stays the
same.
3.5 Which of the following nursing actions will prevent adverse drug events?
A. Use only the trade name when documenting medications.
B. Crush long-acting medications if the patient has dysphagia.
C. After receiving a verbal order, administer the medication and then write
down the order.
D. Use bar code technology according to institutional policy. - answer-D.
Rationale: Using bar code technology in the administration of medications will
decrease medication administration errors.
2.1 A nurse practitioner (NP) has just changed a patient's medication from an
oral form to a patch formulation to avoid the first-pass effect. The NP has
explained it to the patient, but the patient still has questions and asks the
nurse to explain again what is meant by the first-pass effect. The nurse would
be most correct in explaining that this has to do with how
,A. drugs initially bind to plasma proteins
B. initial renal function is involved in drug excretion
C. the way drugs first reach their target cells
D. initial metabolism of an oral drug occurs before it reaches the systemic
circulation - answer-D.
Rationale: The "first-pass effect" involves metabolism of an oral drug in the
liver so that only a portion of a drug dose reaches the systemic circulation and
becomes available to act on target tissues or to be eliminated from the body.
Drug binding to plasma proteins affects drug distribution; an increased amount
of drug has to be absorbed before effective therapeutic levels of unbound drug
are reached.
2.2 A nurse is reading a research report about use of a medication that
describes the pharmacokinetics of a particular medication that a patient is
taking. Pharmacokinetics involves
A. drug effects on human cells
B. drug binding with receptors
C. drug absorption, distribution, metabolism, and elimination
D. drug stimulation of normal cell functions - answer-C.
Rationale: Pharmacokinetics involves movement of a drug through the body
and its elimination. Drug binding with receptors and drug effects on cells are
pharmacodynamic processes. Drug stimulation of normal cell functions
describes an agonist drug.
2.3 A nurse is caring for a man who has worsening liver disease. In monitoring
his medication, it is important to know that a patient with liver disease may
have impaired drug
A. absorption
, B. distribution
C. metabolism
D. excretion - answer-C.
Rationale: The liver is mainly involved in drug metabolism. The gastrointestinal
tract is mainly involved in absorption of oral drugs, the cardiovascular system is
concerned with distribution, and the kidneys are concerned with excretion.
2.4 A nurse is looking up information about the effects of a drug on different
receptors. Characteristics of receptors include which of the following?
A. They are carbohydrates located in cell membranes or inside cells.
B. They are constantly synthesized and degraded in the body.
C. They bind with molecules of any drug circulating in the bloodstream.
D. They regulate the actions of all drugs. - answer-D.
Rationale: Receptors are mainly proteins that are manufactured and
eliminated like other proteins in the body. Their numbers and binding
capacities can be increased or decreased in particular situations. Most
receptors bind with relatively few drugs. Some drugs do not require receptor
binding for their actions (e.g., antacids such as TUMS or Mylanta).
3.6 A nurse is administering an elixir. Which of the following measures is
appropriate?
A. microgram
B. milligram
