Introduction to Pharmacology - GCU
Actual Questions and Answers
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Multiple-Choice (A–D), For Each Question.
Each Question Includes The Correct Answer
Expert-Verified explanation
,Which medication would the nurse plan on educating the patient
about if the nurse notes from the patient's chart that the primary
health care provider is considering adding a tricyclic antidepressant
(TCA) to the patient's treatment regimen?
A. Doxepin
B. Trazodone
C. Amoxapine
D. Maprotiline
Correct Answer: A. Doxepin
Expert Rationale: Doxepin is classified as a tricyclic antidepressant (TCA),
which functions by inhibiting the reuptake of norepinephrine and serotonin
in the central nervous system, thereby enhancing neurotransmitter levels
and improving mood. Trazodone is classified as a serotonin antagonist and
reuptake inhibitor (SARI), not a TCA. Amoxapine and maprotiline, though
sometimes categorized with TCAs due to structural similarities, have
atypical profiles and are less commonly used as prototypical TCAs. Thus,
education would primarily focus on doxepin when a TCA is ordered.
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Which medication does the nurse anticipate administering to a patient
with a suspected overdose of oxazepam?
A. Naloxone
,B. Naltrexone
C. Nalmefene
D. Flumazenil
Correct Answer: D. Flumazenil
Expert Rationale: Oxazepam is a benzodiazepine. Flumazenil acts as a
specific benzodiazepine receptor antagonist and is used as an antidote in
benzodiazepine overdose by competitively inhibiting the action of
benzodiazepines at GABA receptor sites. Naloxone, naltrexone, and
nalmefene are opioid antagonists and are not effective for benzodiazepine
toxicity.
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Which system would the nurse assess to determine whether
bethanechol has had a therapeutic effect?
A. Gastric
B. Urinary
C. Muscular
D. Neurologic
Correct Answer: B. Urinary
Expert Rationale: Bethanechol is a direct-acting cholinergic agonist
primarily indicated for the management of postoperative and postpartum
, nonobstructive urinary retention. Assessment of therapeutic effect is based
upon improved urinary output and bladder emptying, reflecting the drug's
action on the detrusor muscle of the bladder.
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By which age do the processes of gastric emptying and
gastrointestinal (GI) motility, which are unpredictable in neonates and
infants, approach those of adults?
A. 6–8 months
B. 9–10 months
C. 11–12 months
D. 13–14 months
Correct Answer: A. 6–8 months
Expert Rationale: Infants demonstrate variable and delayed gastric
emptying and gastrointestinal motility due to immature digestive function.
Studies show that these processes begin to approximate adult patterns by
6–8 months of age, impacting drug absorption and pharmacokinetics.
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Which action is recommended to reduce the chances of drug toxicity
in older adult patients?