NR507- Midterm Advanced Patho- cardiac, pulmonary,
hematology, renal
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Hematopoiesis - (correct Answer) - blood cell formation
Fetus- liver and spleen
Adult- bone marrow
Anemia - (correct Answer) - A condition in which the blood is deficient in red blood cells, in hemoglobin,
or in total volume.
Erythropoiesis - (correct Answer) - formation of red blood cells
In kidney in response to hypoxia
macrocytic normochromic anemia - (correct Answer) - Large RBC's, normal hemoglobin
Folic acid or Vitamin B12 deficiency
microcytic hypochromic anemia - (correct Answer) - small, abnormally shaped erythrocytes that are not
able to carry normal hemoglobin
Thalassemia- mediterranean
normocytic normochromic anemia - (correct Answer) - Characterized by red cells that are relatively
normal in size and normal hemoglobin
Aplastic, hemorrhagic, hemolytic, sickle cell
iron deficiency anemia - (correct Answer) - anemia resulting when there is not enough iron to build
hemoglobin for red blood cells
Affects children, poverty, child bearing age
Erythrocytes - (correct Answer) - red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
, Mitotic division- 100-120 days
sickle cell anemia - (correct Answer) - A genetic disorder in which erythroctyes take on an abnormal
curved or "sickle" shape (Hb-s)
Thalassemia - (correct Answer) - Inherited defect in the ability to produce hemoglobin, usually seen in
persons of Mediterranean background.
pernicious anemia - (correct Answer) - Lack of mature erythrocytes caused by inability to absorb vitamin
B12 into the bloodstream
hemolytic anemia - (correct Answer) - Characterized by an inadequate number of circulating red blood
cells due to the premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
Erythropoietin (EPO) - (correct Answer) - Hormone secreted by the kidney to stimulate the production of
red blood cells by bone marrow
In response to hypoxia
In the fetus the liver produces this
Hemoglobin - (correct Answer) - Iron-containing protein in red blood cells that carries oxygen for delivery
to cells
4 molecules of O2
Made of polypeptide, heme, iron
anemia due to gastrectomy - (correct Answer) - Iron def anemia is major cause after this
Removal of stomach often leads to marked decrease in production of gastric acid. This acid is necessary
to convert dietary iron to a form that is more readily absorbed by the duodenum
hemolytic anemia causes - (correct Answer) - Sickle cell disease, ABO or Rh incompatibility, drug induced
Role of macrophages - (correct Answer) - Innate:
1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells, inflammation, fever, etc.
Adaptive:
1. Phagocytosis: opsonization with complement or Abs
hematology, renal
Save
Hematopoiesis - (correct Answer) - blood cell formation
Fetus- liver and spleen
Adult- bone marrow
Anemia - (correct Answer) - A condition in which the blood is deficient in red blood cells, in hemoglobin,
or in total volume.
Erythropoiesis - (correct Answer) - formation of red blood cells
In kidney in response to hypoxia
macrocytic normochromic anemia - (correct Answer) - Large RBC's, normal hemoglobin
Folic acid or Vitamin B12 deficiency
microcytic hypochromic anemia - (correct Answer) - small, abnormally shaped erythrocytes that are not
able to carry normal hemoglobin
Thalassemia- mediterranean
normocytic normochromic anemia - (correct Answer) - Characterized by red cells that are relatively
normal in size and normal hemoglobin
Aplastic, hemorrhagic, hemolytic, sickle cell
iron deficiency anemia - (correct Answer) - anemia resulting when there is not enough iron to build
hemoglobin for red blood cells
Affects children, poverty, child bearing age
Erythrocytes - (correct Answer) - red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
, Mitotic division- 100-120 days
sickle cell anemia - (correct Answer) - A genetic disorder in which erythroctyes take on an abnormal
curved or "sickle" shape (Hb-s)
Thalassemia - (correct Answer) - Inherited defect in the ability to produce hemoglobin, usually seen in
persons of Mediterranean background.
pernicious anemia - (correct Answer) - Lack of mature erythrocytes caused by inability to absorb vitamin
B12 into the bloodstream
hemolytic anemia - (correct Answer) - Characterized by an inadequate number of circulating red blood
cells due to the premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
Erythropoietin (EPO) - (correct Answer) - Hormone secreted by the kidney to stimulate the production of
red blood cells by bone marrow
In response to hypoxia
In the fetus the liver produces this
Hemoglobin - (correct Answer) - Iron-containing protein in red blood cells that carries oxygen for delivery
to cells
4 molecules of O2
Made of polypeptide, heme, iron
anemia due to gastrectomy - (correct Answer) - Iron def anemia is major cause after this
Removal of stomach often leads to marked decrease in production of gastric acid. This acid is necessary
to convert dietary iron to a form that is more readily absorbed by the duodenum
hemolytic anemia causes - (correct Answer) - Sickle cell disease, ABO or Rh incompatibility, drug induced
Role of macrophages - (correct Answer) - Innate:
1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells, inflammation, fever, etc.
Adaptive:
1. Phagocytosis: opsonization with complement or Abs
