HMX Pharmacology EXAM COMPLETE
ACTUAL QUESTIONS AND VERIFIED
SOLUTIONS LATEST UPDATE THIS YEAR |
A+ GRADE – RECENTLY RELEASED
1. The cells that line the intestines are referred to as
the__ which have a specialized role in the absorption of
nutrients (Basics) - ANSWER ✓ intestinal epithelial cells
2. The kidneys filter the blood and produce a __ which is
similar in composition to plasma. It is this filtrate that will,
after modification by the functional units of the kidneys,
form the urine. (Basics) - ANSWER ✓ filtrate
3. In target centered drug discovery if a hit is successful in
the characterization process it becomes a __ - ANSWER
✓ lead compound
4. In target centered drug discovery, lead compounds will
enter __ processes to overcome the deficiencies it may
,have to become a drug candidate - ANSWER ✓
optimization
5. __ centered drug discovery has become the most
common mode of drug dscovery currently used. -
ANSWER ✓ target
6. The aim of __ drug development is to satisfy all of the
requirements that have to be met before a new compound
is deemed ready to be tested in humans - ANSWER ✓
preclinical
7. In preclinical developement, __ testing or discovery
biology is carried out at the molecular and celullar level -
ANSWER ✓ pharmacodynamic
8. In preclinical developement, __ testing or ADME
studies is carried out at the organismal level (on animals) -
ANSWER ✓ pharmacokinetic
9. In preclinical developement, __ testing or safety
pharmacology is carried out at the cellular level and
eventually in an organismal level - ANSWER ✓ toxicity
,10. In preclinical developement, manufacturing or __ is
the final step where the stability of the compound will be
assess on varios conditions to develop a formulation -
ANSWER ✓ pharmaceutical development
11. 99.9% of compounds fail during the __ and will not
move to the preclinical drug development - ANSWER ✓
discovery or design (target or compound drug discovery)
12. After passing discovery phase 60% of drugs fail in the
__ trials. Here the main cause of failure is the safety of the
drug - ANSWER ✓ preclinical
13. After preclinical trials 30% of the drugs fail in the __
trials - ANSWER ✓ clinical
14. The phases of drug development are: __, __, __ -
ANSWER ✓ discovery (target/compound), preclinical trials
(PD, PK, Tx, pharma) and clinical trials (I, II, III, IV)
15. After preclinical development, to iniciate clinical trials
the drug must have __ aproval - ANSWER ✓ IND
(investigational new drug)
, 16. For a drug to pass from phase II clinical trials to phase
IV, it must have __ aprroval - ANSWER ✓ NDA
17. A treatment is referred to as a drug candidate until __
is complete. The treatment is then referred to as an
investigational drug until phase III is complete, and as a
drug after NDA approval. - ANSWER ✓ preclinical
development
18. A treatment is referred to as an investigational drug
until __ is complete. and as a drug after NDA approval. -
ANSWER ✓ phase III
19. A treatment is referred to as as a drug after __
approval. - ANSWER ✓ NDA
20. ideal, patient - ANSWER ✓ Dosage can be distributed
by ideal _______ or the weight of the ________
21. chemical structure, mechanism of action, therapeutic
effect, disease or disorder which the drug treats -
ANSWER ✓ A drug is classified from its ______________
ACTUAL QUESTIONS AND VERIFIED
SOLUTIONS LATEST UPDATE THIS YEAR |
A+ GRADE – RECENTLY RELEASED
1. The cells that line the intestines are referred to as
the__ which have a specialized role in the absorption of
nutrients (Basics) - ANSWER ✓ intestinal epithelial cells
2. The kidneys filter the blood and produce a __ which is
similar in composition to plasma. It is this filtrate that will,
after modification by the functional units of the kidneys,
form the urine. (Basics) - ANSWER ✓ filtrate
3. In target centered drug discovery if a hit is successful in
the characterization process it becomes a __ - ANSWER
✓ lead compound
4. In target centered drug discovery, lead compounds will
enter __ processes to overcome the deficiencies it may
,have to become a drug candidate - ANSWER ✓
optimization
5. __ centered drug discovery has become the most
common mode of drug dscovery currently used. -
ANSWER ✓ target
6. The aim of __ drug development is to satisfy all of the
requirements that have to be met before a new compound
is deemed ready to be tested in humans - ANSWER ✓
preclinical
7. In preclinical developement, __ testing or discovery
biology is carried out at the molecular and celullar level -
ANSWER ✓ pharmacodynamic
8. In preclinical developement, __ testing or ADME
studies is carried out at the organismal level (on animals) -
ANSWER ✓ pharmacokinetic
9. In preclinical developement, __ testing or safety
pharmacology is carried out at the cellular level and
eventually in an organismal level - ANSWER ✓ toxicity
,10. In preclinical developement, manufacturing or __ is
the final step where the stability of the compound will be
assess on varios conditions to develop a formulation -
ANSWER ✓ pharmaceutical development
11. 99.9% of compounds fail during the __ and will not
move to the preclinical drug development - ANSWER ✓
discovery or design (target or compound drug discovery)
12. After passing discovery phase 60% of drugs fail in the
__ trials. Here the main cause of failure is the safety of the
drug - ANSWER ✓ preclinical
13. After preclinical trials 30% of the drugs fail in the __
trials - ANSWER ✓ clinical
14. The phases of drug development are: __, __, __ -
ANSWER ✓ discovery (target/compound), preclinical trials
(PD, PK, Tx, pharma) and clinical trials (I, II, III, IV)
15. After preclinical development, to iniciate clinical trials
the drug must have __ aproval - ANSWER ✓ IND
(investigational new drug)
, 16. For a drug to pass from phase II clinical trials to phase
IV, it must have __ aprroval - ANSWER ✓ NDA
17. A treatment is referred to as a drug candidate until __
is complete. The treatment is then referred to as an
investigational drug until phase III is complete, and as a
drug after NDA approval. - ANSWER ✓ preclinical
development
18. A treatment is referred to as an investigational drug
until __ is complete. and as a drug after NDA approval. -
ANSWER ✓ phase III
19. A treatment is referred to as as a drug after __
approval. - ANSWER ✓ NDA
20. ideal, patient - ANSWER ✓ Dosage can be distributed
by ideal _______ or the weight of the ________
21. chemical structure, mechanism of action, therapeutic
effect, disease or disorder which the drug treats -
ANSWER ✓ A drug is classified from its ______________
