Questions and Answers Rated A+
Any infectious casing agents that cannot be detected using aPCR type reaction? -
ANSWER-Bacteria contai nDNA and we should be able to detect them using PCR,
viruses contain DNA and RNA so can detect. A
A biological causing disease agent consisting of protein (not nucleic acid) Because they
do not contain DNA or RNA so they cannot be detected.
B-lactam antibiotics and why they are good for treating bacterial infections? What is an
advantage? - ANSWER-Antibiotics are natural compounds produced by
microorganisms that kill or inhibit other microorganisms (Slide 37). There are many
types of antibiotics (e.g. Slide 38), beta-lactams are just one of these groups. Beta-
lactams are antibiotics with the beta-lactam ring structure (slide 40).
There are many types of beta-lactam antibiotics, for example ampicillin is one of the
beta-lactam antibiotics. The group beta-lactam antibiotics is one of the largest groups of
antibiotics. Antibiotics can work by "targeting" different parts of the bacteria (Slide 38).
Beta-lactam antibiotics are one of the antibiotics that target cell wall synthesis - this
beta-lactam group of antibiotics control bacteria by preventing bacterial cell wall
production.
Beta-lactamase is an enzyme that breaks down the beta-lactamase ring structure (Slide
38). There are variations on this beta-lactamase enzyme, if a bacteria produces a beta-
lactamase enzyme that breaks down a certain beta-lactam antibiotic then that bacteria
will be resistant to that beta-lactam antibiotic.
See slide 39 of the Microbial Control lecture for information about beta-lactam
antibiotics, including bullet point 3 that talks about one of their advantages.
Can 2 sugar molecules have different configuration despite having same molecular
formula? - ANSWER-2 sugar molecules that have the same formula, but have different
confirmations (D form and L form). Additionally, slide 64 shows a number of D form
sugar molecules where each molecule has the same molecular formula but each
molecule has a different configuration (linear form verses cyclic structure in alpha form
verses cyclic structure in beta form)
demonstrate your broad knowledge of Biomedical science by briefly summarising a
relevant article that you have read about? - ANSWER-BIOMEDICAL SCIENCE
ARTICLE SUMMARISED FOR EXAM
Molecular Genetics of Mycobacteria - By Graham F. Hatfull, William R. Jacobs
, This journal takes an in-depth look at the disease tuberculosis, which is caused by the
bacteria Mycobacterium tuberculosis. Which causes one in four avoidable deaths in the
developing world and kills ore adults than malaria and AIDS combined. It also looks at
advances in mycobacterial genetics and what is being don to develop new drugs and
vaccines that look promising in being able to treat this disease.
he diagnosis and management of Diabetes mellitus is only of concern to a very small
portion of the health care industry". (Hint, you should first decide if this statement is true
or false, then BRIEFLY explain why it is true or false.) - ANSWER-Think about how
many areas of the health care industry are involved in the diagnosis and management
of DM. Who requests screening tests for patients, who collects patient specimens, who
processes the specimens in that lab, who makes a diagnosis, who is involved in follow
up testing, who is involved in monitoring patients, who is involved in treating a patient
with an acute health problem as a result of DM, who is involved in helping individual
patients with DM manage their long term healthcare, who is involved in diagnosing or
treating a patient's complications caused by DM, who is involved in trying to reduce the
incidence of DM in communities/ nationally/ globally, who is involved in trying to
understand the disease better to improve management in the future, who is involved in
developing better drugs or better ways of delivering existing drugs, etc?
This is just a selection of some areas of the health industry that might be involved in
patients of populations that have or may get the condition. Your answer does not need
to be long or exhaustive, you just need to show that you have thought about this and
realize that lots of different health care workers can be involved in the diagnosis and
management of disease.
how are bacteria resistant r become resistant to antibiotics? - ANSWER-some bacteria
in a population might be already resistant for example if a bacteria produces the beta -
lactase enzyme then that bacteria can be resistant to beta lactic antibiotics such as
penicillin.
how does ionising radiation effect microbes to kill them - ANSWER-damages the DNA,
hence killing the microbes
How does skin protect against bacteria? - ANSWER-A number ways.
• It provides a physical barrier.
• Additionally, there is an array of immune cells involved with this organ that help to
protect us.
• Additionally, the normal flora of the skin can help to protect us from pathogenic
organisms by competing with these pathogens and in some cases by secreting
substances that inhibit the growth of foreign microbes.
• Additionally, the conditions on skin might make it more difficult for foreign microbes to
take survive or take hold. In summer increased salt (sweat) will inhibit some potential
pathogen despite there being more oil and moisture present. In winter, the skin may be
drier and less nutrients available. So it can be difficult for foreign microbes to grow.