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Neurology Practice Questions 2025–2026 | Verified Neuro Q&A with Rationales | NCLEX & Med-Surg Nursing Exam | Graded A+

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Ace your neurology exams with this up-to-date study pack featuring high-yield neurology practice questions and correct answers, fully aligned with the latest guidelines. All questions are already graded and verified, covering topics such as stroke, seizures, MS, Parkinson’s, cranial nerves, and neuro assessments. Perfect for nursing, medical, and allied health students. Boost your scores with exam-ready, NCLEX-style Q&A backed by detailed rationales and expert updates.

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Neurology Practice Questions Questions
and Correct Answers/ Latest Update /
Already Graded
History & Physical/Neurology

A 73 year-old male presents to the clinic with his wife. His wife has
noticed that he has developed a resting tremor in his right hand and a
shuffling gait over the last year. What finding on physical examination
would support your suspected diagnosis?

Answers

A. Chorea

B. Dystonia

C. Masked facies

D. Hyperreflexia

Ans: Explanations
(u) A. See C for explanation.
(u) B. See C for explanation.
(c) C. The patient symptoms are consistent with Parkinsonism.
Physical exam findings include masked facies, micrographia,
decreased arm swing, and monotonous speech.
(u) D. See C for explanation.


History & Physical/Neurology

All rights reserved © 2025/ 2026 |

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A patient with an upper motor neuron lesion would exhibit which of the
following findings?

Answers

A. Fasciculations

B. Areflexia

C. Muscular atrophy

D. Spasticity

Ans: Explanations
(u) A. Fasciculations, areflexia and muscle atrophy are
consistent with lower motor neuron lesions.
(u) B. See A for explanations.
(u) C. See A for explanation.
(c) D. Spasticity is an upper motor neuron lesion finding.


Diagnostic Studies/Neurology

What test is the single most useful test in establishing the diagnosis of
multiple sclerosis?

Answers

A. Cerebral spinal fluid cell count and protein level

B. Cerebral spinal fluid immunoglobulin studies

C. Evoked potentials


All rights reserved © 2025/ 2026 |

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D. Magnetic Resonance Imaging

Ans: Explanations
(u) A. While cerebral spinal fluid cell count, protein levels, and
immunoglobins may be abnormal they are not specific for
multiple sclerosis.
(u) B. See A for explanation.
(u) C. Evoked potentials are most useful in the detection of
subclinical involvement of neuropathways in MS, but does not
establish the diagnosis.
(c) D. The presence of plaques on MRI is a key finding in
establishing the diagnosis of MS.


Diagnostic Studies/Neurology

A 22 year-old male presents to the clinic complaining of excessive
daytime somnolence and strong desires to sleep at inappropriate
times. He came in today because he had an episode of "feeling
paralyzed" as he was falling asleep yesterday. What is the most
appropriate diagnostic test to confirm this patient's diagnosis?

Answers

A. MRI of the brain

B. Electroencephalogram

C. Multiple sleep latency test

D. Overnight polysomnography

All rights reserved © 2025/ 2026 |

, Page |4


Ans: Explanations
(u) A. See C for explanation.
(u) B. See C for explanation.
(c) C. Multiple sleep latency test is required to observe the
abrupt transition to REM sleep and establish the diagnosis of
narcolepsy.
(u) D. See C for explanation.


Diagnosis/Neurology

A 54 year-old male smoker presents to the clinic complaining of
frequent vague headaches with associated vomiting that awaken him
from sleep occasionally and have been present upon awakening for
about two weeks. The headache typically resolves about an hour into
his morning routine. The patient is afebrile. What is the most likely
cause of this patient's headaches?

Answers

A. Cluster headaches

B. Depression

C. Glioblastoma

D. Giant cell arteritis

Ans: Explanations
(u) A. Cluster headaches can awaken patients, but are not
usually "vague".

All rights reserved © 2025/ 2026 |

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