Celiac Exam Questions And Correct
Answers | Already Scored A+ 2025
Screening for Celiac Disease the first step CORRECT ANSWERS There are many
screening blood tests for celiac disease but the most sensitive and commonly used,
whether symptoms are present or not, is the tTG-IgA test
Tissue Transglutaminase Antibodies CORRECT ANSWERS (tTG-IgA) - The tTG-IgA
test will be positive in about 98% of patients with celiac disease who are on a gluten-
containing diet. The same test will come back negative in about 95% of healthy people
without celiac disease. There is a risk of a false positive especially for people with
associated autoimmune disorders like Type 1 diabetes, chronic liver disease,
Hashimoto's thyroiditis, psoriatic or rheumatoid arthritis and heart failure, who do not
have celiac disease.
IgA Endomysial antibody (EMA): CORRECT ANSWERS The EMA test has a specificity
of almost 100%, but is not as sensitive as the tTG-IgA test. About 5-10% of people with
celiac disease do not have a positive EMA test. It is also very expensive in comparison
to the tTG-IgA and requires the use of primate esophagus or human umbilical cord. It is
usually reserved for difficult to diagnose patients.
Total serum IgA CORRECT ANSWERS This test is used to check for IgA deficiency, a
harmless condition associated with celiac disease that can cause a false negative tTG-
IgA or EMA result. If you are IgA deficient, your doctor can order a DGP or tTG-IgG test
Deaminated gliadin peptide (DGP IgA and IgG): CORRECT ANSWERS This test can
be used to further screen for celiac disease in individuals with IgA deficiency or people
who test negative for tTg or EMA antibodies.
Diagnosis of Celiac Disease CORRECT ANSWERS nBlood test first and then do the
biopsy
nONLY way to confirm is by endoscopic biopsy
nPathologist will diagnosis a certain Marsh stage
nAn endoscopic biopsy will tell: CORRECT ANSWERS n1) if you have celiac disease,
n(2) if your symptoms improve on a gluten-free diet due to a placebo effect (you feel
better because you think you should)
(3) if you have a different gastrointestinal disorder or gluten sensitivity which responds
to change in your diet
Marsh 0: CORRECT ANSWERS nThe mucosa (intestinal lining) is normal, so celiac
disease is unlikely. Stage 0 is known as the "pre-infiltrative stage."
Answers | Already Scored A+ 2025
Screening for Celiac Disease the first step CORRECT ANSWERS There are many
screening blood tests for celiac disease but the most sensitive and commonly used,
whether symptoms are present or not, is the tTG-IgA test
Tissue Transglutaminase Antibodies CORRECT ANSWERS (tTG-IgA) - The tTG-IgA
test will be positive in about 98% of patients with celiac disease who are on a gluten-
containing diet. The same test will come back negative in about 95% of healthy people
without celiac disease. There is a risk of a false positive especially for people with
associated autoimmune disorders like Type 1 diabetes, chronic liver disease,
Hashimoto's thyroiditis, psoriatic or rheumatoid arthritis and heart failure, who do not
have celiac disease.
IgA Endomysial antibody (EMA): CORRECT ANSWERS The EMA test has a specificity
of almost 100%, but is not as sensitive as the tTG-IgA test. About 5-10% of people with
celiac disease do not have a positive EMA test. It is also very expensive in comparison
to the tTG-IgA and requires the use of primate esophagus or human umbilical cord. It is
usually reserved for difficult to diagnose patients.
Total serum IgA CORRECT ANSWERS This test is used to check for IgA deficiency, a
harmless condition associated with celiac disease that can cause a false negative tTG-
IgA or EMA result. If you are IgA deficient, your doctor can order a DGP or tTG-IgG test
Deaminated gliadin peptide (DGP IgA and IgG): CORRECT ANSWERS This test can
be used to further screen for celiac disease in individuals with IgA deficiency or people
who test negative for tTg or EMA antibodies.
Diagnosis of Celiac Disease CORRECT ANSWERS nBlood test first and then do the
biopsy
nONLY way to confirm is by endoscopic biopsy
nPathologist will diagnosis a certain Marsh stage
nAn endoscopic biopsy will tell: CORRECT ANSWERS n1) if you have celiac disease,
n(2) if your symptoms improve on a gluten-free diet due to a placebo effect (you feel
better because you think you should)
(3) if you have a different gastrointestinal disorder or gluten sensitivity which responds
to change in your diet
Marsh 0: CORRECT ANSWERS nThe mucosa (intestinal lining) is normal, so celiac
disease is unlikely. Stage 0 is known as the "pre-infiltrative stage."
