Immunology questions from chapters 1 to 8
Chapter (1):
1. Which of the following does NOT protect body surfaces?
A Skin
B Mucus
C Gastric acid
D Salivary amylase
E Gut microflora
2. Pattern recognition receptors (PRR) include which of the following?
A Lipopolysaccharide (LPS)
B Pathogen-associated molecular patterns (PAMPs)
C Lipoteichoic acid
D Lectin-like molecules
E Unmethylated CpG sequences
3. Which of the following does the mononuclear phagocyte system NOT
include?
A Monocytes
B Kupffer cells
C Kidney mesangial cells
D Lymph node medullary macrophages
E Endothelial cells
4. A polymorphonuclear neutrophil (PMN):
A Is a bone marrow stem cell
B Is closely similar to a mast cell
C Contains microbicidal cytoplasmic granules
, D Is not a professional phagocytic cell
E Has granules that stain with eosin
5. Which of the following is NOT produced following activation of the NADPH
oxidase microbicidal pathway?
A O2−
B O2
C H2O2
D NO
E OH
6. Neutrophil defensins are:
A Anti-toxins
B Oxygen-dependent
C Enzymes
D Glycolipids
E Peptide antibiotics
7. The Toll-like receptor 9 (TLR9) pattern recognition receptor recognizes:
A CpG motifs
B Bacterial lipopeptides
C Lipoteichoic acid
D Gram-negative LPS
E dsRNA
8. Complement component C3 is cleaved by:
A C3b
B C3bBb
C Factor B
, D Factor D
E Factor H
9. The membrane attack complex consists of:
A OH
B Colicins
C C3bBb3b
D C5b,6,7,8,9
E Properdin
10. Which of the following statements is TRUE of C3b?
A C3b is chemotactic for neutrophils
B C3b is an anaphylatoxin
C C3b opsonizes bacteria
D C3b directly injures bacteria
E C3b is the inactive form of C3
11. Acute inflammation characteristically involves:
A Constriction of arterioles
B Capillary endothelial cell enlargement
C Influx of macrophages
D Influx of mast cells
E Influx of neutrophils
12. Which of the following statements is TRUE of lysozyme?
A Lysozyme is a cytoplasmic organelle
B Lysozyme activates complement
C Lysozyme is a proteolytic enzyme
D Lysozyme splits peptidoglycan
, E Lysozyme is released by mast cells
13. Which of the following is NOT an acute phase protein?
A Serum amyloid P component
B Chondroitin sulfate
C C-reactive protein
D Mannose-binding lectin
E Fibrinogen
14. Which of the following statements is TRUE of interferons?
A Interferons are found only in mammalian species
B Interferons are divided into five main families
C Interferons induce enzyme synthesis in the target cell
D Interferons only affect infected cells
E Interferons are specific for individual viruses
15. Natural killer (NK) cells do NOT:
A Respond to interferon
B Contain perforin
C Contain tumor necrosis factor (TNF)
D Kill only by damaging the target cell outer membrane
E Contain serine proteases
16. Eosinophils do NOT:
A Stain with basic dyes
B Contain a major basic protein
Chapter (1):
1. Which of the following does NOT protect body surfaces?
A Skin
B Mucus
C Gastric acid
D Salivary amylase
E Gut microflora
2. Pattern recognition receptors (PRR) include which of the following?
A Lipopolysaccharide (LPS)
B Pathogen-associated molecular patterns (PAMPs)
C Lipoteichoic acid
D Lectin-like molecules
E Unmethylated CpG sequences
3. Which of the following does the mononuclear phagocyte system NOT
include?
A Monocytes
B Kupffer cells
C Kidney mesangial cells
D Lymph node medullary macrophages
E Endothelial cells
4. A polymorphonuclear neutrophil (PMN):
A Is a bone marrow stem cell
B Is closely similar to a mast cell
C Contains microbicidal cytoplasmic granules
, D Is not a professional phagocytic cell
E Has granules that stain with eosin
5. Which of the following is NOT produced following activation of the NADPH
oxidase microbicidal pathway?
A O2−
B O2
C H2O2
D NO
E OH
6. Neutrophil defensins are:
A Anti-toxins
B Oxygen-dependent
C Enzymes
D Glycolipids
E Peptide antibiotics
7. The Toll-like receptor 9 (TLR9) pattern recognition receptor recognizes:
A CpG motifs
B Bacterial lipopeptides
C Lipoteichoic acid
D Gram-negative LPS
E dsRNA
8. Complement component C3 is cleaved by:
A C3b
B C3bBb
C Factor B
, D Factor D
E Factor H
9. The membrane attack complex consists of:
A OH
B Colicins
C C3bBb3b
D C5b,6,7,8,9
E Properdin
10. Which of the following statements is TRUE of C3b?
A C3b is chemotactic for neutrophils
B C3b is an anaphylatoxin
C C3b opsonizes bacteria
D C3b directly injures bacteria
E C3b is the inactive form of C3
11. Acute inflammation characteristically involves:
A Constriction of arterioles
B Capillary endothelial cell enlargement
C Influx of macrophages
D Influx of mast cells
E Influx of neutrophils
12. Which of the following statements is TRUE of lysozyme?
A Lysozyme is a cytoplasmic organelle
B Lysozyme activates complement
C Lysozyme is a proteolytic enzyme
D Lysozyme splits peptidoglycan
, E Lysozyme is released by mast cells
13. Which of the following is NOT an acute phase protein?
A Serum amyloid P component
B Chondroitin sulfate
C C-reactive protein
D Mannose-binding lectin
E Fibrinogen
14. Which of the following statements is TRUE of interferons?
A Interferons are found only in mammalian species
B Interferons are divided into five main families
C Interferons induce enzyme synthesis in the target cell
D Interferons only affect infected cells
E Interferons are specific for individual viruses
15. Natural killer (NK) cells do NOT:
A Respond to interferon
B Contain perforin
C Contain tumor necrosis factor (TNF)
D Kill only by damaging the target cell outer membrane
E Contain serine proteases
16. Eosinophils do NOT:
A Stain with basic dyes
B Contain a major basic protein
