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RN ATI Pharmacology Proctored Exam 2025–2026 | 140 Verified Questions + Rationales | NGN-Ready Study Guide

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Ace your RN ATI Pharmacology Proctored Exam 2025–2026 with this expertly crafted Q&A Pack! Includes 140 real-exam-style questions with verified answers and detailed rationales — all aligned with Next Generation NCLEX (NGN) standards. Ideal for nursing students, RN prep, and ATI exam review. What you get: 140 high-yield Pharmacology questions Comprehensive, easy-to-understand answer rationales Covers adverse effects, drug interactions, antidotes, contraindications, NCLEX meds & more Organized in 20-question batches for easy study NGN-Ready: Prioritization, safety, and patient-centered focus Whether you're prepping for ATI, NCLEX, or Med-Surg pharmacology, this guide is a must-have study tool. Perfect for self-study, group sessions, or final review. Trusted by top nursing students!

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RN ATI Pharmacology Proctored Exam 2025–2026 |
140 Verified Questions + Detailed Rationales | NGN-
Ready A+ Pack



1. A nurse is administering morphine IV to a postoperative client. Which
of the following is the priority action?
A. Monitor for constipation
B. Encourage fluid intake
C. ✅ Monitor respiratory rate
D. Assess pain level every 4 hours


🟩 Rationale: Morphine is a CNS depressant. Respiratory depression is
the most serious adverse effect and must be monitored closely.


2. A client prescribed furosemide reports muscle cramps and weakness.
Which lab value should the nurse assess?
A. Sodium
B. Glucose

, 2


C. ✅ Potassium
D. Calcium


🟩 Rationale: Furosemide (Lasix) can cause hypokalemia. Muscle
cramps indicate possible electrolyte imbalance.


3. Which of the following medications requires monitoring for lithium
toxicity when taken concurrently?
A. ✅ Furosemide
B. Lisinopril
C. Acetaminophen
D. Lorazepam


🟩 Rationale: Diuretics can lead to sodium loss, increasing lithium
reabsorption and toxicity risk.


4. A nurse is teaching a client who is prescribed nitroglycerin sublingual
tablets. Which instruction is correct?
A. Take after eating
B. Swallow with water
C. Store in the refrigerator
D. ✅ Place under tongue at onset of chest pain

, 3


🟩 Rationale: Sublingual nitroglycerin should be placed under the
tongue for rapid absorption during angina.


5. Which lab result must be reviewed before administering warfarin?
A. aPTT
B. ✅ INR
C. Platelets
D. Fibrinogen


🟩 Rationale: Warfarin requires INR monitoring to assess therapeutic
anticoagulation and bleeding risk.


6. A nurse is preparing to administer digoxin. The client's HR is 54 bpm.
What should the nurse do?
A. Administer with food
B. Notify the provider
C. ✅ Hold the dose and notify the provider
D. Administer and recheck HR in 15 min


🟩 Rationale: Digoxin can cause bradycardia. Hold if HR is below 60
and notify the provider.

, 4


7. A client is starting levothyroxine. Which finding should the nurse
report immediately?
A. Mild weight loss
B. ✅ Chest pain
C. Increased energy
D. Fine hand tremors


🟩 Rationale: Chest pain may indicate cardiac effects of levothyroxine
and must be reported ASAP.


8. A client taking phenytoin reports gum swelling. What should the nurse
recommend?
A. ✅ Good oral hygiene with soft toothbrush
B. Stop the drug
C. Increase vitamin C
D. Use antiseptic mouthwash


🟩 Rationale: Gingival hyperplasia is a common side effect. Good oral
care helps reduce this risk.


9. A nurse should hold metformin for a client scheduled for which
procedure?
A. Cataract surgery

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