2025/2026 Exam Questions and
Corresponding Answers with Surety of
100% Pass Mark
A nursing student asks the nurse to explain the role of cyclooxygenase-2 (COX-2)
and its role in inflammation. The nurse will explain that COX-2:
a. converts arachidonic acid into a chemical mediator for inflammation.
b. directly causes vasodilation and increased capillary permeability.
c. irritates the gastric mucosa to cause gastrointestinal upset.
d. releases prostaglandins, which cause inflammation and pain in tissues - 🧠
ANSWER ✔✔a. converts arachidonic acid into a chemical mediator for
inflammation
A nursing student asks how nonsteroidal anti-inflammatory drugs (NSAIDs) work
to suppress inflammation and reduce pain. The nurse will explain that NSAIDs:
a. exert direct actions to cause relaxation of smooth muscle.
,b. inhibit the enzyme cyclooxygenase that is necessary for prostaglandin synthesis.
c. interfere with neuronal pathways associated with prostaglandin action.
d. suppress prostaglandin activity by blocking tissue receptor sites. - 🧠 ANSWER
✔✔b. inhibit the enzyme cyclooxygenase that is necessary for prostaglandin
synthesis.
A patient is taking ibuprofen 400 mg every 4 hours to treat moderate arthritis pain
and reports that it is less effective than before. What action will the nurse take?
a. Counsel the patient to discuss a change in dose or changing to a prescription
NSAID with the provider.
b. Recommend adding aspirin to increase the anti-inflammatory effect.
c. Suggest asking the provider about a short course of corticosteroids.
d. Tell the patient to increase the dose to 800 mg every 4 hours. - 🧠 ANSWER
✔✔a. Counsel the patient to discuss a change in dose or changing to a prescription
NSAID with the provider.
A patient who is taking aspirin for arthritis pain asks the nurse why it also causes
gastrointestinal
upset. The nurse understands that this is because aspirin:
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,a. increases gastrointestinal secretions.
b. increases hypersensitivity reactions.
c. inhibits both COX-1 and COX-2.
d. selectively inhibits COX-2. - 🧠 ANSWER ✔✔c. inhibits both COX-1 and COX-
2.
5. A patient is taking aspirin for secondary prevention of myocardial
infarction and is experiencing moderate gastrointestinal upset. The nurse will
contact the patient's
provider to discuss changing from aspirin to which of the following?
a. A COX-2 inhibitor
b. Celecoxib (Celebrex)
c. Enteric-coated aspirin
d. Ibuprofen - 🧠 ANSWER ✔✔c. Enteric-coated aspirin
The nurse is performing a health history on a patient who has arthritis. The patient
reportstinnitus. Suspecting a drug adverse effect, the nurse will ask the patient
about which medication?
a. . Aspirin (Bayer)
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, b. Acetaminophen (Tylenol)
c. Anakinra (Kineret)
d. Prednisone (Deltasone) - 🧠 ANSWER ✔✔a. . Aspirin (Bayer)
The nurse is teaching a patient about using high-dose aspirin to treat arthritis.
Whatinformation
will the nurse include when teaching this patient?
a. "A normal serum aspirin level is between 30 and 40 mg/dL."
b. "You may need to stop taking this drug a week prior to surgery."
c. "You will need to monitor aspirin levels if you are also taking warfarin."
d. "Your stools may become dark, but this is a harmless side effect." - 🧠 ANSWER
✔✔b. "You may need to stop taking this drug a week prior to surgery."
A patient who takes high-dose aspirin to treat rheumatoid arthritis has a serum
salicylate level of
35 mg/dL. The nurse will perform which action?
a. Assess the patient for signs of toxicity, such as tinnitus.
b. Monitor the patient for signs of Reye's syndrome.
c. Notify the provider of severe aspirin toxicity.
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