MMSC 423 Hematology Final Exam
Questions and Answers All Correct
Where does hematopoiesis begin in the embryo?
Liver
Spleen
Yolk Sac
Bone marrow - Answer-Yolk sac
What does CD refer to?
Cellular demarcation
Cluster differentiation
Cluster demarcation
Cellular designation - Answer-Cluster differentiation
Which type of leukocyte comprises the majority of leukocytes in the peripheral blood?
Lymphocytes
Segmented neutrophils
Monocytes
Basophils - Answer-Segmented neutrophils
Where are megakaryocytes found?
Peripheral blood
Bone marrow
Liver
Lymphatic system - Answer-Bone marrow
March hemoglobinuria refers to:
A condition in which persons develop hemoglobinuria after marching or running on hard
surfaces
A condition in which only military personnel develop hemoglobinuria after physical
examination
A condition in which persons develop seasonal hemoglobinuria - Answer-A condition in
which persons develop hemoglobinuria after marching or running on hard surfaces
Which of the following is an integral membrane protein?
Spectrin
Band3
Adducin
,Actin - Answer-Band3
Which of the following abnormal red cell shapes is caused by abnormal lipid distribution
in red cell membrane?
Sickle cells
Spherocytes
Burr cells
Target cells - Answer-Target cells
Which of the following parameters assesses hypochromia?
MCV
Platelet count
MCHC
Osmotic fragility - Answer-MCHC
Which of the following red cells have a teardrop shape?
Drepanocyte
Codocyte
Dacrocyte
Stomatocyte - Answer-Dacrocyte
ADP is secreted from the:
dense granules
beta granules
delta granules
alpha granules - Answer-dense granules
Factor III is known as
prothrombin time
calcium
christmas factor
tissue factor - Answer-tissue factor
Which of the following is true regarding the plasma coagulation zymogens?
- are haptens that induce peptide binding to make larger active molecules
- activation normally occurs throughout the tissues of the body when vascular injury
occurs
- serine proteases that form complexes to activate other zymogens to ultimately
generate thrombin
- circulate normally in their active form - Answer-serine proteases that form complexes
to activate other zymogens to ultimately generate thrombin
What reaction is essential in the production of vitamin K dependent coagulation factors?
reduction of tryptophan
oxidation of valine
gamma carboxylation of glutamic acid
, dehydrogenation of leucine - Answer-gamma carboxylation of glutamic acid
Another name for Factor X is:
Stuart-Prower
Christmas Factor
Fitzgerald Factor
Hagemen Factor - Answer-Stuart-Prower
What happens to the fibrin monomers created when thrombin cleaves fibrinopeptides A
and B from fibrinogen?
digested quickly by tissue plasminogen activator
converted to plasminogen
immediately inactivated to prevent excess clotting
polymerized and are stabilized by FXIIIa - Answer-polymerized and are stabilized by
FXIIIa
A tube of anticoagulated blood was centrifuged. After centrifugation which of the
following describes the correct sequence of layers from top to bottom of the tube?
buffy coat, plasma, red blood cells
buffy coat, red blood cells, plasma
plasma, buffy coat, red blood cells
red blood cells, buffy coat, plasma - Answer-plasma, buffy coat, red blood cells
Factor VII is known as:
fibrinogen
stable factor
christmas factor
labile factor - Answer-stable factor
Tissue Factor Pathway Inhibitor inactivates which factor?
IIa
I
XIa
VIIa - Answer-VIIa
What is the role of the thrombin-thrombomodulin complex?
activates thrombin
inhibits factor Xa
activates protein C
initiates vasoconstriction - Answer-activates protein C
Which of the following comprise the buffy coat?
white blood cells and red blood cells
fibroblasts and red blood cells
lymphocytes and monocytes
platelets and white blood cells - Answer-platelets and white blood cells
Questions and Answers All Correct
Where does hematopoiesis begin in the embryo?
Liver
Spleen
Yolk Sac
Bone marrow - Answer-Yolk sac
What does CD refer to?
Cellular demarcation
Cluster differentiation
Cluster demarcation
Cellular designation - Answer-Cluster differentiation
Which type of leukocyte comprises the majority of leukocytes in the peripheral blood?
Lymphocytes
Segmented neutrophils
Monocytes
Basophils - Answer-Segmented neutrophils
Where are megakaryocytes found?
Peripheral blood
Bone marrow
Liver
Lymphatic system - Answer-Bone marrow
March hemoglobinuria refers to:
A condition in which persons develop hemoglobinuria after marching or running on hard
surfaces
A condition in which only military personnel develop hemoglobinuria after physical
examination
A condition in which persons develop seasonal hemoglobinuria - Answer-A condition in
which persons develop hemoglobinuria after marching or running on hard surfaces
Which of the following is an integral membrane protein?
Spectrin
Band3
Adducin
,Actin - Answer-Band3
Which of the following abnormal red cell shapes is caused by abnormal lipid distribution
in red cell membrane?
Sickle cells
Spherocytes
Burr cells
Target cells - Answer-Target cells
Which of the following parameters assesses hypochromia?
MCV
Platelet count
MCHC
Osmotic fragility - Answer-MCHC
Which of the following red cells have a teardrop shape?
Drepanocyte
Codocyte
Dacrocyte
Stomatocyte - Answer-Dacrocyte
ADP is secreted from the:
dense granules
beta granules
delta granules
alpha granules - Answer-dense granules
Factor III is known as
prothrombin time
calcium
christmas factor
tissue factor - Answer-tissue factor
Which of the following is true regarding the plasma coagulation zymogens?
- are haptens that induce peptide binding to make larger active molecules
- activation normally occurs throughout the tissues of the body when vascular injury
occurs
- serine proteases that form complexes to activate other zymogens to ultimately
generate thrombin
- circulate normally in their active form - Answer-serine proteases that form complexes
to activate other zymogens to ultimately generate thrombin
What reaction is essential in the production of vitamin K dependent coagulation factors?
reduction of tryptophan
oxidation of valine
gamma carboxylation of glutamic acid
, dehydrogenation of leucine - Answer-gamma carboxylation of glutamic acid
Another name for Factor X is:
Stuart-Prower
Christmas Factor
Fitzgerald Factor
Hagemen Factor - Answer-Stuart-Prower
What happens to the fibrin monomers created when thrombin cleaves fibrinopeptides A
and B from fibrinogen?
digested quickly by tissue plasminogen activator
converted to plasminogen
immediately inactivated to prevent excess clotting
polymerized and are stabilized by FXIIIa - Answer-polymerized and are stabilized by
FXIIIa
A tube of anticoagulated blood was centrifuged. After centrifugation which of the
following describes the correct sequence of layers from top to bottom of the tube?
buffy coat, plasma, red blood cells
buffy coat, red blood cells, plasma
plasma, buffy coat, red blood cells
red blood cells, buffy coat, plasma - Answer-plasma, buffy coat, red blood cells
Factor VII is known as:
fibrinogen
stable factor
christmas factor
labile factor - Answer-stable factor
Tissue Factor Pathway Inhibitor inactivates which factor?
IIa
I
XIa
VIIa - Answer-VIIa
What is the role of the thrombin-thrombomodulin complex?
activates thrombin
inhibits factor Xa
activates protein C
initiates vasoconstriction - Answer-activates protein C
Which of the following comprise the buffy coat?
white blood cells and red blood cells
fibroblasts and red blood cells
lymphocytes and monocytes
platelets and white blood cells - Answer-platelets and white blood cells
