ONS Chemotherapy Immunotherapy Certificate Test Questions
with Verified Answers
Define neoadjuvant therapy - ANSWER - Streptozocin (Zanosar)
Treatment is given prior to surgery to shrink the
tumor
Hypersensitivity can occur with late doses of: -
ANSWER -Carboplatin
Define adjuvant therapy - ANSWER -
Additional cancer treatment given after the
primary treatment to lower the risk that the
cancer reoccur These agents are typically categorized as highly
emetogenic: - ANSWER -1. Alkylating
agents
2. Nitrosoureas
3 subcategories of alkylating agents: -
ANSWER -1. Nitrogen mustards
2. Platinum-based agents (do not possess an
alkyl group but still termed alkylating agents as Pre-administration labs for alkylating agents and
they work similarly) nitrosoureas: - ANSWER -BUN
3. Nitrosoureas Creatinine
CBC w/ diff
Common alkylating agents: - ANSWER -
Cyclophosphamide (Cytoxan) What is the medication Mesna used for? -
Ifosfamide (Ifex) ANSWER -Bladder protectant with
Bendamustine (Treanda) administration of cyclophosphamide or ifosfamide
Common platinum-based agents: - Instruct pts receiving ________ to avoid
ANSWER -Cisplatin (Platinol) exposure to cold air and consuming cold fluids for
Carboplatin (Paraplatin) 3-4 days following treatment - ANSWER -
Oxaliplatin
What is unique about nitrosoureas agents? -
ANSWER -Able to cross the blood-brain How do antimetabolites function? -
barrier; can be effective in treating some brain ANSWER -By blocking DNA and RNA
tumors growth by interfering with enzymes needed for
normal cell metabolism
Common nitrosoureas agents: - ANSWER -
Carmustine (BiCNU) Antimetabolites work in the ___ phase. -
Lomustine (CeeNu) ANSWER -S
, ONS Chemotherapy Immunotherapy Certificate Test Questions
with Verified Answers
Idarubicin
Common side effects of antimetabolites: -
ANSWER -Myelosuppression The antitumor abx ___________ is not an
GI toxicities anthracycline, but has anthracycline-type
Photosensitivity properties. - ANSWER -Mitoxantrone
Hand-foot syndrome
Common non-anthracycline antitumor abx: -
Common antimetabolite drugs: - ANSWER -Actinomycin D
ANSWER -Azacitidine Mitomycin C
Capecitabine Bleomycin
5-FU
Cytarabine
Decitabine
Methotrexate Monitoring necessary with doxorubicin: -
ANSWER -Vesicant --> extravasation
Cardiac function
Lifetime dose tracking (cardiotoxicity)
The institute for Safe Medication Practices
recommends what route of administration for
vincristine? - ANSWER -IV piggyback via
gravity Lifetime dose of doxorubicin should not exceed: -
ANSWER -550 mg/m^2
Anthracycline antitumor abx work by: -
ANSWER -Interfering with enzymes What cardiac protectant medication can be
necessary for DNA to replicate in ALL phases of administered prior to doxorubicin? -
the cell cycle ANSWER -Dexrazoxane
The two major classifications of antitumor Significant side effects of doxorubicin are: -
antibiotics are: - ANSWER -Anthracyclines ANSWER -Cardiotoxicity
Non-anthracyclines N/V
Mucositis
Diarrhea
Severe myelosuppression
Common anthracycline antitumor abx: - Hepatic impairment
ANSWER -Daunorubicin Secondary cancers
Doxorubicin
Epirubicin
with Verified Answers
Define neoadjuvant therapy - ANSWER - Streptozocin (Zanosar)
Treatment is given prior to surgery to shrink the
tumor
Hypersensitivity can occur with late doses of: -
ANSWER -Carboplatin
Define adjuvant therapy - ANSWER -
Additional cancer treatment given after the
primary treatment to lower the risk that the
cancer reoccur These agents are typically categorized as highly
emetogenic: - ANSWER -1. Alkylating
agents
2. Nitrosoureas
3 subcategories of alkylating agents: -
ANSWER -1. Nitrogen mustards
2. Platinum-based agents (do not possess an
alkyl group but still termed alkylating agents as Pre-administration labs for alkylating agents and
they work similarly) nitrosoureas: - ANSWER -BUN
3. Nitrosoureas Creatinine
CBC w/ diff
Common alkylating agents: - ANSWER -
Cyclophosphamide (Cytoxan) What is the medication Mesna used for? -
Ifosfamide (Ifex) ANSWER -Bladder protectant with
Bendamustine (Treanda) administration of cyclophosphamide or ifosfamide
Common platinum-based agents: - Instruct pts receiving ________ to avoid
ANSWER -Cisplatin (Platinol) exposure to cold air and consuming cold fluids for
Carboplatin (Paraplatin) 3-4 days following treatment - ANSWER -
Oxaliplatin
What is unique about nitrosoureas agents? -
ANSWER -Able to cross the blood-brain How do antimetabolites function? -
barrier; can be effective in treating some brain ANSWER -By blocking DNA and RNA
tumors growth by interfering with enzymes needed for
normal cell metabolism
Common nitrosoureas agents: - ANSWER -
Carmustine (BiCNU) Antimetabolites work in the ___ phase. -
Lomustine (CeeNu) ANSWER -S
, ONS Chemotherapy Immunotherapy Certificate Test Questions
with Verified Answers
Idarubicin
Common side effects of antimetabolites: -
ANSWER -Myelosuppression The antitumor abx ___________ is not an
GI toxicities anthracycline, but has anthracycline-type
Photosensitivity properties. - ANSWER -Mitoxantrone
Hand-foot syndrome
Common non-anthracycline antitumor abx: -
Common antimetabolite drugs: - ANSWER -Actinomycin D
ANSWER -Azacitidine Mitomycin C
Capecitabine Bleomycin
5-FU
Cytarabine
Decitabine
Methotrexate Monitoring necessary with doxorubicin: -
ANSWER -Vesicant --> extravasation
Cardiac function
Lifetime dose tracking (cardiotoxicity)
The institute for Safe Medication Practices
recommends what route of administration for
vincristine? - ANSWER -IV piggyback via
gravity Lifetime dose of doxorubicin should not exceed: -
ANSWER -550 mg/m^2
Anthracycline antitumor abx work by: -
ANSWER -Interfering with enzymes What cardiac protectant medication can be
necessary for DNA to replicate in ALL phases of administered prior to doxorubicin? -
the cell cycle ANSWER -Dexrazoxane
The two major classifications of antitumor Significant side effects of doxorubicin are: -
antibiotics are: - ANSWER -Anthracyclines ANSWER -Cardiotoxicity
Non-anthracyclines N/V
Mucositis
Diarrhea
Severe myelosuppression
Common anthracycline antitumor abx: - Hepatic impairment
ANSWER -Daunorubicin Secondary cancers
Doxorubicin
Epirubicin
