NCLEX-PN Infection Control & Safety Test Bank 2025–2026 | 150
NGN-Style Questions + Rationales | A+ Guaranteed Pass
1. A nurse is caring for a client with tuberculosis (TB) in a hospital
setting. Which type of isolation precautions should be implemented?
A. Contact precautions
B. Standard precautions only
C. Airborne precautions
D. Droplet precautions
Correct Answer: C
Rationale: TB is transmitted via airborne particles, requiring airborne
precautions including a negative-pressure room and N95 respirator.
Contact or droplet precautions are insufficient for TB.
,2. During a routine assessment, a nurse notices that a confused elderly
patient keeps attempting to get out of bed unassisted. What is the priority
intervention?
A. Apply wrist restraints
B. Increase sedation dosage
C. Implement a bed alarm system
D. Assign the client to a shared room
Correct Answer: C
Rationale: A bed alarm helps ensure immediate staff response without
violating the patient’s autonomy or safety. Restraints and sedation are
last-resort options and pose additional risks.
3. A client with Clostridioides difficile (C. diff) infection requires
assistance with toileting. Which action by the nurse demonstrates correct
infection control?
A. Use of alcohol-based sanitizer after care
B. Wearing a surgical mask
,C. Placing the client in airborne isolation
D. Washing hands with soap and water
Correct Answer: D
Rationale: C. diff spores are not effectively removed with alcohol-based
sanitizer. Handwashing with soap and water is required after contact
with the patient or their environment.
4. What is the correct sequence for donning personal protective
equipment (PPE)?
A. Gloves → Gown → Mask → Goggles
B. Gown → Mask → Goggles → Gloves
C. Mask → Gloves → Goggles → Gown
D. Gown → Goggles → Mask → Gloves
Correct Answer: B
Rationale: The CDC-recommended order is gown first, followed by
mask, goggles or face shield, and gloves last. This ensures complete
coverage and prevents contamination.
, 5. A nurse is teaching a new graduate about preventing needle stick
injuries. Which statement indicates correct understanding?
A. "I should recap the needle with one hand after use."
B. "I should dispose of the needle immediately in a sharps
container."
C. "I can recap the needle before placing it in a sharps bin."
D. "Needles can be thrown into the regular trash if capped."
Correct Answer: B
Rationale: All used needles should go directly into an approved sharps
container without recapping, which reduces the risk of needle stick
injuries and exposure to bloodborne pathogens.
6. A nurse is caring for a client with measles. Which action is
appropriate to prevent disease transmission?
A. Wearing a surgical mask when entering the room
B. Using an N95 respirator and negative-pressure room
NGN-Style Questions + Rationales | A+ Guaranteed Pass
1. A nurse is caring for a client with tuberculosis (TB) in a hospital
setting. Which type of isolation precautions should be implemented?
A. Contact precautions
B. Standard precautions only
C. Airborne precautions
D. Droplet precautions
Correct Answer: C
Rationale: TB is transmitted via airborne particles, requiring airborne
precautions including a negative-pressure room and N95 respirator.
Contact or droplet precautions are insufficient for TB.
,2. During a routine assessment, a nurse notices that a confused elderly
patient keeps attempting to get out of bed unassisted. What is the priority
intervention?
A. Apply wrist restraints
B. Increase sedation dosage
C. Implement a bed alarm system
D. Assign the client to a shared room
Correct Answer: C
Rationale: A bed alarm helps ensure immediate staff response without
violating the patient’s autonomy or safety. Restraints and sedation are
last-resort options and pose additional risks.
3. A client with Clostridioides difficile (C. diff) infection requires
assistance with toileting. Which action by the nurse demonstrates correct
infection control?
A. Use of alcohol-based sanitizer after care
B. Wearing a surgical mask
,C. Placing the client in airborne isolation
D. Washing hands with soap and water
Correct Answer: D
Rationale: C. diff spores are not effectively removed with alcohol-based
sanitizer. Handwashing with soap and water is required after contact
with the patient or their environment.
4. What is the correct sequence for donning personal protective
equipment (PPE)?
A. Gloves → Gown → Mask → Goggles
B. Gown → Mask → Goggles → Gloves
C. Mask → Gloves → Goggles → Gown
D. Gown → Goggles → Mask → Gloves
Correct Answer: B
Rationale: The CDC-recommended order is gown first, followed by
mask, goggles or face shield, and gloves last. This ensures complete
coverage and prevents contamination.
, 5. A nurse is teaching a new graduate about preventing needle stick
injuries. Which statement indicates correct understanding?
A. "I should recap the needle with one hand after use."
B. "I should dispose of the needle immediately in a sharps
container."
C. "I can recap the needle before placing it in a sharps bin."
D. "Needles can be thrown into the regular trash if capped."
Correct Answer: B
Rationale: All used needles should go directly into an approved sharps
container without recapping, which reduces the risk of needle stick
injuries and exposure to bloodborne pathogens.
6. A nurse is caring for a client with measles. Which action is
appropriate to prevent disease transmission?
A. Wearing a surgical mask when entering the room
B. Using an N95 respirator and negative-pressure room
