,Chapterm01:mDrugmRegulation,mActions,mandmResponses
Workmanm&mLaCharity:mUnderstandingmPharmacology:mEssentialsmformMedicationmSafety,m2n
dmEdition
MULTIPLEmCHOICEmB
ASICmCONCEPTS
1. Whichmhealthmcaremprofessionalmhasmthemmajormresponsibilitymformdispensingmprescrib
edmdrugsmundermthemdirectionmofmampharmacist?
a. Physician
b Nursempractitioner
.
c. Licensedmnurse
d Pharmacymtechnician
.
ANS:m D
Themphysicianmandmnursempractitionermhavemthemmajormresponsibilitymformprescribingmdrugs,mnotm
dispensingmthem.mThemlicensedmnursemhasmthemprimarymresponsibilitymformadministeringmdrugs,mal
thoughmundermsomemcircumstancesmamlicensedmnursemmaymdispensemprescribedmdrugsmbutmthismismn
otmhismormhermmajormresponsibilityminmdrugmtherapy.mThempharmacymtechnicianmhasmthemmajormres
ponsibilitymofmdispensingmprescribedmdrugsmundermthemdirectionmofmamlicensedmpharmacist.
DIF: CognitivemLevel:mRemembering REF: p.m3
2. Whichmtermmdescribesmthemeffectmofmamdrugmthatmimprovesmbodymfunction?
a. Sidemeffect
b Intendedmaction
.
c. Adversemreaction
d Idiosyncraticmresponse
.
ANS:m B
Thempurposemofmdrugmtherapymismtomtakemamdrugmtomprevent,mreduce,mormcorrectmamhealthmproblem.m
Thismresponsemismanymdrug’smintendedmactionmalsomknownmasmamtherapeuticmresponse.
DIF: CognitivemLevel:mRemembering REF: p.m3
3. Whichmtypemofmdrugmnamemism“owned”mbymthemcompanymthatmmanufacturesmit?
a. Genericmname
b Chemicalmname
, .
c. Categorymname
d Trademname
.
ANS:m D
Themchemicalmnamemismamdrug’smexactmchemicalmcomposition.mThemgenericmnamemismthemnamemas
signedmtomthemdrugmbymthemU.S.mAdoptedmNamesmCouncilmandmismnotmownedmbymanyone.mThemcat
egorymnamemrefersmtomthemtypemofmdrugm(whatmitmdoesmormwhatmitmismusedmfor)mandmismnotmanmactual
mdrugmname.mThemtrademnamem(brandmname)mismthemnamemprovidedmandmownedmbymamspecificmdru
g’smmanufacturer.
DIF: CognitivemLevel:mRemembering REF: p.m4
4. Whichmdrugmormdrugmclassmismam“highmalert”mdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:m B
Amhighmalertmdrugmismoneminmwhichmharmmismlikelymtomresultmifmgivenmatmthemwrongmdose,mtomthemwr
ongmpatient,mormnotmgivenmtomthemcorrectmpatient.mDrugsmclassifiedmasmhighmalertmdrugsmincludempot
assium,mnarcoticsm(opioids),minsulin,mcancermchemotherapymdrugs,mandmheparinm(ormanymdrugmthatm
stronglymaffectsmbloodmclotting).mPenicillin,mNSAIDs,mandmcalciummaremnotmconsideredmhighmalertm
drugs.
DIF: CognitivemLevel:mRemembering REF: p.m4
5. Whatmismthemtermmformamdrugmthatmhasmthemsamemactionmasmamnaturallymoccurringmbo
dymhormonemormenzyme?
a. Agonist
b Blockingmagent
.
c. Chemical
d Duplicator
.
ANS:m A
Amdrugmagonistmismanmextrinsicmdrugmthatmactivatesmthemreceptormsitesmofmamcellmandmmimicsmthemac
tionsmofmnaturallymoccurringmbodymsubstancesm(intrinsicmdrugs).mAmblockingmagentmismamdrug
, antagonist.mAmchemicalmwouldmnotmnecessarilymbemamdrugmatmall.mAmduplicatormismnotmampharmacolo
gicmterm.
DIF: CognitivemLevel:mRemembering REF: pp.m6-7
6. Whichmtermmdescribesmhowmthembodymaffectsmdrugmactivity?
a. Drugmpotency
b Pharmacodynamics
.
c. Therapeuticmeffect
d Pharmacokinetics
.
ANS:m D
Themtermmpharmacokineticsmrefersmtomdrugmmetabolismmandmhowmthembodymchangesmamdrug.mPha
rmacodynamicsmrefersmtomhowmamdrugmworksmtomchangembodymfunction.mDrugmpotencymrefersmtomh
owmstronglymormtomwhatmdegreemamdrugmexertsmitsmeffects.mThemtherapeuticmeffectmismclosermtompha
rmacodynamics,mmeaningmhowmamdrugmworksmtomchangembodymfunction.
DIF: CognitivemLevel:mRemembering REF: p.m10
7. InmthemUnitedmStates,mwhichmgroupmismresponsiblemformenforcingmestablishedmstandardsmf
ormdrugmmanufacturing?
a. U.S.mPharmacopeia
b NationalmInstitutesmofmHealth
.
c. FoodmandmDrugmAdministration
d AssociationmofmPharmaceuticalmManufacturers
.
ANS:m C
ThemstandardsmformdrugmmanufacturemaremestablishedmbymthemU.S.mPharmacopeia.mThesemstandar
dsmaremenforcedmbymthemFoodmandmDrugmAdministration.mNeithermthemNationalmInstitutesmofmHealt
hmnormthemAssociationmofmPharmaceuticalmManufacturersmhasmanymauthoritymtomenforcemdrugmsta
ndards.
DIF:m m CognitivemLevel:mRememberingm m m m REF:m m p.m5
8. Whichmfactormismammajormdisadvantagemofmthemtransdermalmdrugmdeliverymroute?
a. Onlymamprescribermcanmadministermdrugsmbymthemtransdermalmrout
e.
b Transdermalmdrugsmmustmbemsterilemrathermthanmclean.
.
c. Firstmpassmdrugmlossmbymthismroutemismthemmostmextensive.
d Drugmabsorptionmismdependentmonmadequatemcirculation.
Workmanm&mLaCharity:mUnderstandingmPharmacology:mEssentialsmformMedicationmSafety,m2n
dmEdition
MULTIPLEmCHOICEmB
ASICmCONCEPTS
1. Whichmhealthmcaremprofessionalmhasmthemmajormresponsibilitymformdispensingmprescrib
edmdrugsmundermthemdirectionmofmampharmacist?
a. Physician
b Nursempractitioner
.
c. Licensedmnurse
d Pharmacymtechnician
.
ANS:m D
Themphysicianmandmnursempractitionermhavemthemmajormresponsibilitymformprescribingmdrugs,mnotm
dispensingmthem.mThemlicensedmnursemhasmthemprimarymresponsibilitymformadministeringmdrugs,mal
thoughmundermsomemcircumstancesmamlicensedmnursemmaymdispensemprescribedmdrugsmbutmthismismn
otmhismormhermmajormresponsibilityminmdrugmtherapy.mThempharmacymtechnicianmhasmthemmajormres
ponsibilitymofmdispensingmprescribedmdrugsmundermthemdirectionmofmamlicensedmpharmacist.
DIF: CognitivemLevel:mRemembering REF: p.m3
2. Whichmtermmdescribesmthemeffectmofmamdrugmthatmimprovesmbodymfunction?
a. Sidemeffect
b Intendedmaction
.
c. Adversemreaction
d Idiosyncraticmresponse
.
ANS:m B
Thempurposemofmdrugmtherapymismtomtakemamdrugmtomprevent,mreduce,mormcorrectmamhealthmproblem.m
Thismresponsemismanymdrug’smintendedmactionmalsomknownmasmamtherapeuticmresponse.
DIF: CognitivemLevel:mRemembering REF: p.m3
3. Whichmtypemofmdrugmnamemism“owned”mbymthemcompanymthatmmanufacturesmit?
a. Genericmname
b Chemicalmname
, .
c. Categorymname
d Trademname
.
ANS:m D
Themchemicalmnamemismamdrug’smexactmchemicalmcomposition.mThemgenericmnamemismthemnamemas
signedmtomthemdrugmbymthemU.S.mAdoptedmNamesmCouncilmandmismnotmownedmbymanyone.mThemcat
egorymnamemrefersmtomthemtypemofmdrugm(whatmitmdoesmormwhatmitmismusedmfor)mandmismnotmanmactual
mdrugmname.mThemtrademnamem(brandmname)mismthemnamemprovidedmandmownedmbymamspecificmdru
g’smmanufacturer.
DIF: CognitivemLevel:mRemembering REF: p.m4
4. Whichmdrugmormdrugmclassmismam“highmalert”mdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:m B
Amhighmalertmdrugmismoneminmwhichmharmmismlikelymtomresultmifmgivenmatmthemwrongmdose,mtomthemwr
ongmpatient,mormnotmgivenmtomthemcorrectmpatient.mDrugsmclassifiedmasmhighmalertmdrugsmincludempot
assium,mnarcoticsm(opioids),minsulin,mcancermchemotherapymdrugs,mandmheparinm(ormanymdrugmthatm
stronglymaffectsmbloodmclotting).mPenicillin,mNSAIDs,mandmcalciummaremnotmconsideredmhighmalertm
drugs.
DIF: CognitivemLevel:mRemembering REF: p.m4
5. Whatmismthemtermmformamdrugmthatmhasmthemsamemactionmasmamnaturallymoccurringmbo
dymhormonemormenzyme?
a. Agonist
b Blockingmagent
.
c. Chemical
d Duplicator
.
ANS:m A
Amdrugmagonistmismanmextrinsicmdrugmthatmactivatesmthemreceptormsitesmofmamcellmandmmimicsmthemac
tionsmofmnaturallymoccurringmbodymsubstancesm(intrinsicmdrugs).mAmblockingmagentmismamdrug
, antagonist.mAmchemicalmwouldmnotmnecessarilymbemamdrugmatmall.mAmduplicatormismnotmampharmacolo
gicmterm.
DIF: CognitivemLevel:mRemembering REF: pp.m6-7
6. Whichmtermmdescribesmhowmthembodymaffectsmdrugmactivity?
a. Drugmpotency
b Pharmacodynamics
.
c. Therapeuticmeffect
d Pharmacokinetics
.
ANS:m D
Themtermmpharmacokineticsmrefersmtomdrugmmetabolismmandmhowmthembodymchangesmamdrug.mPha
rmacodynamicsmrefersmtomhowmamdrugmworksmtomchangembodymfunction.mDrugmpotencymrefersmtomh
owmstronglymormtomwhatmdegreemamdrugmexertsmitsmeffects.mThemtherapeuticmeffectmismclosermtompha
rmacodynamics,mmeaningmhowmamdrugmworksmtomchangembodymfunction.
DIF: CognitivemLevel:mRemembering REF: p.m10
7. InmthemUnitedmStates,mwhichmgroupmismresponsiblemformenforcingmestablishedmstandardsmf
ormdrugmmanufacturing?
a. U.S.mPharmacopeia
b NationalmInstitutesmofmHealth
.
c. FoodmandmDrugmAdministration
d AssociationmofmPharmaceuticalmManufacturers
.
ANS:m C
ThemstandardsmformdrugmmanufacturemaremestablishedmbymthemU.S.mPharmacopeia.mThesemstandar
dsmaremenforcedmbymthemFoodmandmDrugmAdministration.mNeithermthemNationalmInstitutesmofmHealt
hmnormthemAssociationmofmPharmaceuticalmManufacturersmhasmanymauthoritymtomenforcemdrugmsta
ndards.
DIF:m m CognitivemLevel:mRememberingm m m m REF:m m p.m5
8. Whichmfactormismammajormdisadvantagemofmthemtransdermalmdrugmdeliverymroute?
a. Onlymamprescribermcanmadministermdrugsmbymthemtransdermalmrout
e.
b Transdermalmdrugsmmustmbemsterilemrathermthanmclean.
.
c. Firstmpassmdrugmlossmbymthismroutemismthemmostmextensive.
d Drugmabsorptionmismdependentmonmadequatemcirculation.
