NR547 Final Exam

NR54744Final44Exam
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1. Medications44for44depression:44SSR
Is44SNRIs
SDRIs
44TCAs

44MAOI

s
2. SSRIs:44-Action:44inhibit445-HT44reuptake
-Examples:44citalopram,44escitalopram,44fluoxetine,44paroxetine,44sertraline
-Adverse44effects:
• nausea
• agitation
• diarrhea
• headache
• weight44gain
• sexual44side44effects
3. SNRIs:44-inhibit445-HT44reuptake
-inhibit44NE44reuptake44(‘44energy,44focus)
-increase44DA44in44prefrontal44cortex44(‘44cognition)
-Examples:44desvenlafaxine,44duloxetine,44levomilnacipran,44venlafaxine
-Adverse44effects:
• elevated44blood44pressure
• nausea
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual44dysfunction
4. SDRIs:44-inhibit44DA44reuptake44(‘alertness,44motivation)
-inhibit44NE44reuptake44(‘energy)
-Adverse44effects:
• agitation
• headache
• dry44mouth
• constipation
• weight44loss
5. TCAs:44-
Action:44inhibits44the44reuptake44of44serotonin44and44norepinephrine;44blocks44nore
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pinephrine, 44histamine,44and44acetylcholine44receptors

-Examples:44amitriptyline,44clomipramine,44desipramine,44doxepin




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-Common44Side44Effects:
• dry44mouth
• constipation
• blurred44vision
• urinary44 retention
• sedation
• weight44gain
• hypotension
• tachycardia
• sexual44dysfunction
6. MAOIs:44-
Action:44increases44norepinephrine44and44serotonin44by44inhibiting44the44enzyme44that44i
nactivates44it
-Examples:44isocarboxazid,44phenelzine,44tranylcypromine
-Common44Side44Effects:
• sedation
• dizziness
• sexual44dysfunction
• hypertensive44crisis
7. Prescribing44pearls:44citalopram44(Celexa):44mild44antihistamine44effects
8. Prescribing44pearls:44escitalopram44(Lexapro):44no44known44drug44interactions
9. Prescribing44pearls:44fluoxetine44(Prozac):44longest44half-life
10. Prescribing44pearls:44paroxetine44(Paxil):44also44treats44social44anxiety44and44insom
nia
11. Prescribing44pearls:44fluvoxamine44(Luvox):44treats44anxious44depression44smo
kers44require44increased44dose
12. Prescribing44pearls:44sertraline44(Zoloft):44also44treats44social44anxiety44and44h
yper-44somnolence
13. Prescribing44pearls:44bupropion44(Wellbutrin):44NDRI44may44improve44energy,44
alert-
44ness,44and44motivation;44not44first44line44treatment44for44anxiety;44contraindicated44in4

4clients44with44a44history44of44seizures

14. Prescribing44pearls:44duloxetine44(Cymbalta):44effective44for44atypical44pain44at44hi
gher44doses;44appropriate44for44clients44who44present44with44somatic44symptoms44of44d
epression;44effective44for44atypical44pain,44such44as44fibromyalgia44and44diabetic44neur
opathy
15. Prescribing44pearls:44venlafaxine44(Effexor):44treats44both44depression44and44an
xiety44disorders,44ensure44trial44of44higher44dose44before44switching44to44a44different44m
edication
16. Prescribing44pearls:44desvenlafaxine44(Pristiq):44effective44for44perimenopau
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sal44vasomotor 44symptoms

17. considered44when44selecting44a44medication::44-Client44preference
-Prior44treatment44response
-Anticipated44adverse44effects




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