BCH 361 - Exam 3 Question and
answers rated A+ 2025
________ is responsible for producing glucose when blood glucose is ____. -
correct answer ✔Gluconeogenesis, low.
Gluconeogenesis is mostly carried out in the ______. - correct answer
✔Liver.
The liver is responsible for... - correct answer ✔maintaining blood glucose
level.
Gluconeogenesis precursors include: - correct answer ✔Pyruvate.
Derivatives of certain amino acids.
Glycerol from lipid metabolism.
Glycerol can be converted to ______ by ______ ______. - correct answer
✔G3P, triose kinase.
Gluconeogenesis needs _____ nucleotide triphosphates to produce a single
molecule of glucose. - correct answer ✔Six.
(T/F) Most enzymes in gluconeogenesis are also glycolysis enzymes. - correct
answer ✔True.
_____________ is used to reverse PFK in the cytoplasm. - correct answer
✔Fructose 1,6 bisphosphatase.
, G6P is transported into ER lumen, where __________ dephosphorylates G6P
to produce glucose. - correct answer ✔Glucose 6-phosphatase.
________ and _______ are needed to reverse pyruvate kinase. - correct
answer ✔Pyruvate carboxylase, PEP carboxykinase (PEPCK).
In mitochondria, pyruvate carboxylase converts pyruvate to _______ through
carboxylation. - correct answer ✔Oxaloacetate.
An ATP is hydrolyzed and the cofactor biotin is used as the activated carrier of
CO2 by the enzyme to transfer the carboxyl group to pyruvate.
Oxaloacetate produced in mitochondria must be transported into cytoplasm by
reducing it to ____ using ________. - correct answer ✔Malate, malate
dehydrogenase.
The resulting malate is then transported into the cytoplasm and converted
back to _____ by ___________. - correct answer ✔Oxaloacetate, malate
dehydrogenase.
Finally, ______ decarboxylates and phosphorylates oxaloacetate to produce
_____. - correct answer ✔PEPCK, PEP.
The regulation of gluconeogenesis is mainly through __________. - correct
answer ✔Fructose 1,6-bisphosphatase.
Fructose 1,6-bisphosphatase is inhibited by... - correct answer ✔F2, 6BP.
Fructose 1,6-bisphosphatase is activated by... - correct answer ✔Citrate.
answers rated A+ 2025
________ is responsible for producing glucose when blood glucose is ____. -
correct answer ✔Gluconeogenesis, low.
Gluconeogenesis is mostly carried out in the ______. - correct answer
✔Liver.
The liver is responsible for... - correct answer ✔maintaining blood glucose
level.
Gluconeogenesis precursors include: - correct answer ✔Pyruvate.
Derivatives of certain amino acids.
Glycerol from lipid metabolism.
Glycerol can be converted to ______ by ______ ______. - correct answer
✔G3P, triose kinase.
Gluconeogenesis needs _____ nucleotide triphosphates to produce a single
molecule of glucose. - correct answer ✔Six.
(T/F) Most enzymes in gluconeogenesis are also glycolysis enzymes. - correct
answer ✔True.
_____________ is used to reverse PFK in the cytoplasm. - correct answer
✔Fructose 1,6 bisphosphatase.
, G6P is transported into ER lumen, where __________ dephosphorylates G6P
to produce glucose. - correct answer ✔Glucose 6-phosphatase.
________ and _______ are needed to reverse pyruvate kinase. - correct
answer ✔Pyruvate carboxylase, PEP carboxykinase (PEPCK).
In mitochondria, pyruvate carboxylase converts pyruvate to _______ through
carboxylation. - correct answer ✔Oxaloacetate.
An ATP is hydrolyzed and the cofactor biotin is used as the activated carrier of
CO2 by the enzyme to transfer the carboxyl group to pyruvate.
Oxaloacetate produced in mitochondria must be transported into cytoplasm by
reducing it to ____ using ________. - correct answer ✔Malate, malate
dehydrogenase.
The resulting malate is then transported into the cytoplasm and converted
back to _____ by ___________. - correct answer ✔Oxaloacetate, malate
dehydrogenase.
Finally, ______ decarboxylates and phosphorylates oxaloacetate to produce
_____. - correct answer ✔PEPCK, PEP.
The regulation of gluconeogenesis is mainly through __________. - correct
answer ✔Fructose 1,6-bisphosphatase.
Fructose 1,6-bisphosphatase is inhibited by... - correct answer ✔F2, 6BP.
Fructose 1,6-bisphosphatase is activated by... - correct answer ✔Citrate.
