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Q1. An 82-year-old presents with memory loss and difficulty completing daily
activities. Which initial lab should be ordered to rule out a reversible cause?
A) Serum calcium
B) Cobalamin (Vitamin B12)
C) Thyroid ultrasound
D) MRI brain
Answer: B
Rationale: Vitamin B12 deficiency (cobalamin) can mimic dementia and should be
screened first.
Q2. Which lab is commonly included in the dementia work-up to rule out
metabolic contributors?
A) Serum folate and B12
B) Cortisol stimulation test
C) Blood cultures
D) Coagulation studies
Answer: A
Rationale: Folate and B12 deficiency can cause cognitive impairment.
Q3. A dementia evaluation includes TSH. Why?
A) Hyperthyroidism causes Parkinson’s
B) Hypothyroidism can mimic depression or dementia
,C) TSH screening is only routine for older adults
D) To evaluate liver function
Answer: B
Rationale: Hypothyroidism often presents with memory loss, apathy, and slowed
cognition.
Q4. Which finding best differentiates dementia from depression?
A) Impaired recent memory
B) Apathy and social withdrawal
C) Long duration of symptoms before seeking care
D) Poor appetite
Answer: C
Rationale: Dementia develops gradually; depression usually prompts earlier
medical help.
Q5. The hallmark of delirium is:
A) Loss of recent memory only
B) Gradual decline in executive function
C) Inattention and fluctuating consciousness
D) Social withdrawal over months
Answer: C
Rationale: Delirium = acute onset, fluctuating consciousness, inattention.
Q6. A patient reports 3 months of sadness, low energy, poor appetite, and
difficulty concentrating. Cognitive testing shows inconsistent effort and intact
remote memory. Most likely diagnosis?
A) Major depressive disorder (“pseudodementia”)
B) Alzheimer’s dementia
, C) Delirium
D) Wernicke’s encephalopathy
Answer: A
Rationale: Depression can mimic dementia (pseudodementia), but memory
improves with treatment.
Q7. Which memory test question best assesses recent memory?
A) “What year were you born?”
B) “What did you eat for dinner last night?”
C) “What was your first job?”
D) “Who was the first U.S. president?”
Answer: B
Rationale: Asking about last night’s meal tests recent memory.
Q8. In delirium, the level of consciousness is:
A) Stable and unchanged
B) Variable and fluctuating
C) Always deeply impaired
D) Normal but inattentive
Answer: B
Rationale: Delirium features fluctuating LOC and inattention.
Q9. Which factor increases risk for delirium in hospitalized older adults?
A) Longstanding hypertension
B) Immobility and sensory impairment
C) Daily exercise and social engagement
D) High educational level