COMSAE 110 Verified Multiple Choice and
Conceptual Actual Emended Exam Questions
With Reviewed 100% Correct Detailed Answers
Guaranteed Pass!!Current Update
Q1. A ranch worker presents with black eschar and surrounding edema. Gram
stain shows Gram-positive rods in chains. Most likely organism?
A) Clostridium perfringens
B) Bacillus anthracis
C) Listeria monocytogenes
D) Corynebacterium diphtheriae
Answer: B
Rationale: Bacillus anthracis → Gram + rods in chains, cutaneous anthrax causes
black eschar.
Q2. A hospitalized patient develops a pulmonary infection after working in a wool
factory. Which organism is most likely responsible?
A) Aspergillus
B) Bacillus anthracis
C) Mycobacterium tuberculosis
D) Klebsiella pneumoniae
Answer: B
Rationale: Pulmonary anthrax = “woolsorter’s disease.”
Q3. A patient presents with epistaxis, purpura, and gingival bleeding. Labs:
anemia, ↓Hgb, ↓Hct. Most likely underlying mechanism?
A) Platelet membrane abnormality
B) Coagulation factor deficiency
,C) Hemolysis
D) Vitamin K deficiency
Answer: A
Rationale: Platelet membrane defects → mucocutaneous bleeding signs.
Q4. A 26-year-old male presents with a painless cystic scrotal mass above the
testis. It transilluminates. Most likely diagnosis?
A) Varicocele
B) Hydrocele
C) Spermatocele
D) Testicular tumor
Answer: C
Rationale: Spermatocele = cystic mass in epididymis that transilluminates.
Q5. Histology of a comedone from a patient with acne vulgaris would show:
A) Hyperkeratosis with melanocytes
B) Sebum and keratin in hair follicle
C) Granulomatous inflammation
D) Malignant keratinocytes
Answer: B
Rationale: Acne comedones → keratin and sebum clogging follicles.
Q6. A toddler presents with progressive proximal lower limb weakness. Genetic
testing reveals mutation in SMN1 gene on chromosome 5. Diagnosis?
A) Duchenne muscular dystrophy
B) Becker muscular dystrophy
C) Spinal muscular atrophy
D) Myotonic dystrophy
Answer: C
Rationale: SMA → anterior horn cell loss, SMN1 mutation.
Q7. A 3-year-old child with continuous machine-like murmur in the left upper
sternal border. Diagnosis?
,A) Atrial septal defect
B) Patent ductus arteriosus
C) Ventricular septal defect
D) Mitral regurgitation
Answer: B
Rationale: PDA → continuous “machinery” murmur.
Q8. A patient with a history of myocardial infarction presents with large Q waves
on ECG. What does this finding suggest?
A) Acute ischemia
B) Old infarct
C) Left bundle branch block
D) Pericarditis
Answer: B
Rationale: Q waves = old infarction.
Q9. A patient uses phenylephrine nasal spray for 7 days and develops worsening
congestion. Mechanism?
A) Anticholinergic effect
B) Tachyphylaxis of α-adrenergic receptors
C) Bacterial superinfection
D) Histamine release
Answer: B
Rationale: Rebound congestion from downregulation of α-adrenergic receptors.
Q10. A patient with hyperlipidemia is prescribed a drug that inhibits HMG-CoA
reductase. Which class is this?
A) Statins
B) Fibrates
, C) Niacin
D) Cholestyramine
Answer: A
Rationale: Statins inhibit HMG-CoA reductase.
Q11. Concurrent use of a macrolide antibiotic and statin puts a patient at risk for:
A) Pancreatitis
B) Rhabdomyolysis
C) Hypokalemia
D) Hepatitis A
Answer: B
Rationale: Statins + macrolides inhibit statin metabolism → ↑ risk of
rhabdomyolysis.
Q12. Which of the following is a macrolide antibiotic?
A) Ciprofloxacin
B) Azithromycin
C) Ceftriaxone
D) Gentamicin
Answer: B
Rationale: Azithromycin is a macrolide; others are fluoroquinolone,
cephalosporin, aminoglycoside.
Q13. A patient with ARDS will show which histological feature?
A) Hyaline membranes in alveoli
B) Caseating granulomas
C) Pulmonary emboli
D) Bronchiectasis
Answer: A
Rationale: Hyaline membranes = hallmark of ARDS.
Conceptual Actual Emended Exam Questions
With Reviewed 100% Correct Detailed Answers
Guaranteed Pass!!Current Update
Q1. A ranch worker presents with black eschar and surrounding edema. Gram
stain shows Gram-positive rods in chains. Most likely organism?
A) Clostridium perfringens
B) Bacillus anthracis
C) Listeria monocytogenes
D) Corynebacterium diphtheriae
Answer: B
Rationale: Bacillus anthracis → Gram + rods in chains, cutaneous anthrax causes
black eschar.
Q2. A hospitalized patient develops a pulmonary infection after working in a wool
factory. Which organism is most likely responsible?
A) Aspergillus
B) Bacillus anthracis
C) Mycobacterium tuberculosis
D) Klebsiella pneumoniae
Answer: B
Rationale: Pulmonary anthrax = “woolsorter’s disease.”
Q3. A patient presents with epistaxis, purpura, and gingival bleeding. Labs:
anemia, ↓Hgb, ↓Hct. Most likely underlying mechanism?
A) Platelet membrane abnormality
B) Coagulation factor deficiency
,C) Hemolysis
D) Vitamin K deficiency
Answer: A
Rationale: Platelet membrane defects → mucocutaneous bleeding signs.
Q4. A 26-year-old male presents with a painless cystic scrotal mass above the
testis. It transilluminates. Most likely diagnosis?
A) Varicocele
B) Hydrocele
C) Spermatocele
D) Testicular tumor
Answer: C
Rationale: Spermatocele = cystic mass in epididymis that transilluminates.
Q5. Histology of a comedone from a patient with acne vulgaris would show:
A) Hyperkeratosis with melanocytes
B) Sebum and keratin in hair follicle
C) Granulomatous inflammation
D) Malignant keratinocytes
Answer: B
Rationale: Acne comedones → keratin and sebum clogging follicles.
Q6. A toddler presents with progressive proximal lower limb weakness. Genetic
testing reveals mutation in SMN1 gene on chromosome 5. Diagnosis?
A) Duchenne muscular dystrophy
B) Becker muscular dystrophy
C) Spinal muscular atrophy
D) Myotonic dystrophy
Answer: C
Rationale: SMA → anterior horn cell loss, SMN1 mutation.
Q7. A 3-year-old child with continuous machine-like murmur in the left upper
sternal border. Diagnosis?
,A) Atrial septal defect
B) Patent ductus arteriosus
C) Ventricular septal defect
D) Mitral regurgitation
Answer: B
Rationale: PDA → continuous “machinery” murmur.
Q8. A patient with a history of myocardial infarction presents with large Q waves
on ECG. What does this finding suggest?
A) Acute ischemia
B) Old infarct
C) Left bundle branch block
D) Pericarditis
Answer: B
Rationale: Q waves = old infarction.
Q9. A patient uses phenylephrine nasal spray for 7 days and develops worsening
congestion. Mechanism?
A) Anticholinergic effect
B) Tachyphylaxis of α-adrenergic receptors
C) Bacterial superinfection
D) Histamine release
Answer: B
Rationale: Rebound congestion from downregulation of α-adrenergic receptors.
Q10. A patient with hyperlipidemia is prescribed a drug that inhibits HMG-CoA
reductase. Which class is this?
A) Statins
B) Fibrates
, C) Niacin
D) Cholestyramine
Answer: A
Rationale: Statins inhibit HMG-CoA reductase.
Q11. Concurrent use of a macrolide antibiotic and statin puts a patient at risk for:
A) Pancreatitis
B) Rhabdomyolysis
C) Hypokalemia
D) Hepatitis A
Answer: B
Rationale: Statins + macrolides inhibit statin metabolism → ↑ risk of
rhabdomyolysis.
Q12. Which of the following is a macrolide antibiotic?
A) Ciprofloxacin
B) Azithromycin
C) Ceftriaxone
D) Gentamicin
Answer: B
Rationale: Azithromycin is a macrolide; others are fluoroquinolone,
cephalosporin, aminoglycoside.
Q13. A patient with ARDS will show which histological feature?
A) Hyaline membranes in alveoli
B) Caseating granulomas
C) Pulmonary emboli
D) Bronchiectasis
Answer: A
Rationale: Hyaline membranes = hallmark of ARDS.
