NSG 552 Psychopharmacology – Key Terms and Class Notes Weeks 1-3 – Wilkes University

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NSG552 / NSG 552
Key Terms
and
Class Notes Week 1-3
Psychopharmacology - Wilkes

This PDF contains:
 Psychopharmacology Key Terms

 Psychopharmacology Class Notes Week 1-3

 Everything in Here to Pass the Exam

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, Key Terms

Week 1: Introduction to Psychopharmacology


PHARMACOKINETICS- THE BODY'S ACTION ON THE DRUG


Absorption

Distribution

Excretion

Metabolism

Cytochrome (CYP)-450 - CYP enzymes are estimated to account for the
biotransformation of about 60% of the most commonly prescribed drugs in
America. These enzymes are primarily in the liver and are classified according
to family (1, 2, or 3) and isoform. There are six important enzymes (pathways)
in psychopharmacology expressed in this nomenclature:

● CYP1A2
● CYP2B6
● CYP2C9
● CYP2C19
● CYP2D6
● CYP3A4

PHARMACODYNAMICS- THE DRUG'S ACTION ON THE BODY


Four mechanisms for this action:

Enzyme activity

Nonspecific chemical or physical interactions

Acting as antimetabolites-

, 2


Binding to cell receptors- Receptors are proteins that bind to compounds
generating cellular signals


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Stahl's Essential Psychopharmacology

● Chapters 1-3
o These chapters will provide a review of the necessary
neurobiology and neurochemistry that will be required for
adequate comprehension of course concepts and material

Key Terms

● Pharmacokinetics
● Pharmacodynamics
● First-generation antipsychotic
● Second-generation antipsychotic
● EPS and Tardive Dyskinesia
● Upregulation and Downregulation
● Receptor profiles
● Binding
● Affinity
● CYP450
● Dopamine pathways
● Metabolic syndrome
● High-potency vs Low-potency
● Neuroleptic malignant syndrome (NMS)
● QTc interval