Conceptual Actual Emended Exam Questions With
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1. What is fibroadenoma? - ANSWER Benign breast lesion of fibrotic stroma
(connective tissue) & glandular tissue; heterogenous lesion AKA benign breast dz (BBD)
2. What is etiology of fibroadenoma? - ANSWER Unknown, thought to be exaggerated
response to normal hormonal stimuli
3. What is the most common benign tumor in female breast? - ANSWER
Fibroadenoma (most common 15-40yo, but can be any age)
4. What are some risk factors for fibroadenoma? - ANSWER -Multiple FA's associated
w/rare ca syndromes (Maffuci syndrome, Cowden syndrome, Carney complex)
-Increased risk of BBD with h/o adolescent ETOH consumption, esp. >/=10g per day
5. What are some assessment findings of BBD? - ANSWER -Discrete, painless, firm/rubbery
mass w/well-defined borders
-Freely mobile
-Fluctuations in size w/pregn. or menst. cycle
->5cm considered giant FA
-No nipple discharge
6. What are some diff dx for BBD? - ANSWER -Fibrocystic breast dz
,-Intraductal papilloma
-Breast ca
-Phyllodes tumor
-Cyst
-Other benign breast dz
7. What are some diagnostic studies for BBD? - ANSWER -Mammo
-US
-Fine needle bx
-Open bx
8. What are some nonpharm options for BBD? - ANSWER -Conservative observation, pt
reassurance
-Surgical excision if >3cm, symptomatic, or if dx questionable due to imaging findings such as
irreg. borders or abnormal vascularity.
-Cryoablation
9. What are some pharm options for BBD? - ANSWER There are none
10. Does BBD affect lactation? - ANSWER No
11. When is consult/referral recommended for BBD? - ANSWER Surgical for excision of
giant FA, symptomatic lesions, lesions w/questionable findings on imaging
12. What are follow-up rec's for BBD? - ANSWER Conservative management: US q6mo x2y
after disovery
,Postop as rec. by surgeon
13. What is expected course for BBD? - ANSWER -May undergo spontaneous involution
due to hormonal changes in younger/postmen.
-Subsequent lesions after involution require complete workup as new lesion.
-Complete resolution after surgical removal, but recurrence possible.
14. What are possible complications for BBD? - ANSWER -Progression to malignancy if not
excised
-Postop complications: infection, formation of scar tissue
15. What is fibrocystic breast dz? - ANSWER -Spectrum of changes: cyst formation,
columnar cell changes, mastalgia, apocrine metaplasia, sclerosing adenosis, blunt duct adenosis,
epithelial hyperplasia, atypical ductal/lobular hyperplasia
-One of heterogenous lesions encompassed by term benign breast dz (BBD)
16. What are possible causes of FBD? - ANSWER -Luteal phase defect
-Increased estrogen
-Hyperprolactinemia
-Hypersensitivity to estrogen
-Sensitivity to methylxanthines
-Dietary fat intake
17. What is typical age of FBD? - ANSWER Premenop. 30-50yo
18. What are some risk factors for FBD? - ANSWER -None definitively
-Possible methylxanthine ingestion (caffeine, chocolate, etc.)
, -Increased risk in pt's with h/o adolescent ETOH consumption (>/=10g/day)
19. What are assessment findings of FBD? - ANSWER -Maybe asymptom.
-Palpation of smooth, movable masses, may vary in size
-Vague areas of breast thickening/ridges
-Breast pain/discomfort/tenderness, diminishes after menses
-Breasts feeling full, swollen, heavy, engorged
-Worsening of symptoms premenstr.
-Nipple discharge (varying color/consistency)
20. What are diff. dx for FBD? - ANSWER -Breast ca
-Intraductal papillomas
-FA
-Mastitis
-Chest wall syndrome
-Neuralgia
21. What are diagnostic studies for FBD? - ANSWER -Prolactin level
-TSH
-Mammo
-US
-Needle/open bx
-Maybe galactography (ductography) when nipple discharge present
22. What are some nonpharm options for FBD? - ANSWER -Eval to rule out malign.
-Therapeutic aspiration of cysts