COMSAE Form 113 Practice Exam
Version 2 Questions And Correct
Answers (Verified Answers) Plus
Rationales 2025 Q&A | Instant
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1. A 45-year-old man presents with sharp epigastric pain radiating to the
back. Serum lipase is elevated. Which of the following is the most likely
diagnosis?
A. Cholecystitis
B. Acute pancreatitis
C. Peptic ulcer disease
D. Gastritis
Acute pancreatitis presents with epigastric pain radiating to the back and
elevated lipase levels.
2. A 3-year-old child presents with a barking cough and inspiratory stridor.
What is the most appropriate next step in management?
A. Intubation
B. Chest X-ray
C. Racemic epinephrine nebulization
,D. Antibiotics
Croup is managed initially with corticosteroids and racemic epinephrine in
moderate to severe cases.
3. A 60-year-old man has fatigue and macrocytic anemia. His MCV is 112 fL.
Which of the following deficiencies is most likely?
A. Iron
B. Folate
C. Vitamin C
D. Vitamin B12
Vitamin B12 deficiency causes macrocytic anemia and neurologic
symptoms.
4. Which structure is derived from the first pharyngeal arch?
A. Stapes
B. Hyoid bone (lesser horn)
C. Maxilla
D. Cricoid cartilage
The maxilla arises from the first pharyngeal arch.
5. A patient is found to have elevated TSH and low free T4. What is the
most likely diagnosis?
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Sick euthyroid syndrome
Elevated TSH and low free T4 indicates primary hypothyroidism.
,6. A man with schizophrenia believes the TV is sending him messages. This
is an example of which symptom?
A. Hallucination
B. Delusion of reference
C. Disorganized speech
D. Catatonia
Delusion of reference involves belief that neutral stimuli (e.g., TV) have
personal meaning.
7. Which of the following bacteria produces a toxin that inhibits protein
synthesis by inactivating EF-2?
A. Clostridium tetani
B. Bacillus anthracis
C. Corynebacterium diphtheriae
D. Bordetella pertussis
Diphtheria toxin inhibits elongation factor 2, halting protein synthesis.
8. A 72-year-old woman has hip pain and elevated alkaline phosphatase. X-
ray shows thickened trabeculae. What is the most likely diagnosis?
A. Osteoarthritis
B. Paget disease of bone
C. Osteoporosis
D. Rickets
Paget disease shows abnormal bone remodeling and high ALP with normal
calcium/phosphorus.
, 9. Which of the following drugs inhibits dihydrofolate reductase?
A. Sulfamethoxazole
B. Ciprofloxacin
C. Trimethoprim
D. Rifampin
Trimethoprim inhibits bacterial DHFR, impairing folate synthesis.
10. A patient with a renal mass and polycythemia has elevated
erythropoietin. What is the most likely tumor?
A. Transitional cell carcinoma
B. Renal cell carcinoma
C. Wilms tumor
D. Oncocytoma
RCC can produce ectopic erythropoietin, causing secondary polycythemia.
11. A 28-year-old woman has infertility and oligomenorrhea. Labs show
elevated LH/FSH ratio. What is the most likely diagnosis?
A. Endometriosis
B. Hypothyroidism
C. Polycystic ovary syndrome (PCOS)
D. Hyperprolactinemia
PCOS typically presents with oligomenorrhea, infertility, and elevated
LH/FSH ratio.
12. A patient with hypertension and hypokalemia has suppressed renin
and elevated aldosterone. What is the most likely diagnosis?
A. Renovascular hypertension
B. Primary hyperaldosteronism
Version 2 Questions And Correct
Answers (Verified Answers) Plus
Rationales 2025 Q&A | Instant
Download Pdf
1. A 45-year-old man presents with sharp epigastric pain radiating to the
back. Serum lipase is elevated. Which of the following is the most likely
diagnosis?
A. Cholecystitis
B. Acute pancreatitis
C. Peptic ulcer disease
D. Gastritis
Acute pancreatitis presents with epigastric pain radiating to the back and
elevated lipase levels.
2. A 3-year-old child presents with a barking cough and inspiratory stridor.
What is the most appropriate next step in management?
A. Intubation
B. Chest X-ray
C. Racemic epinephrine nebulization
,D. Antibiotics
Croup is managed initially with corticosteroids and racemic epinephrine in
moderate to severe cases.
3. A 60-year-old man has fatigue and macrocytic anemia. His MCV is 112 fL.
Which of the following deficiencies is most likely?
A. Iron
B. Folate
C. Vitamin C
D. Vitamin B12
Vitamin B12 deficiency causes macrocytic anemia and neurologic
symptoms.
4. Which structure is derived from the first pharyngeal arch?
A. Stapes
B. Hyoid bone (lesser horn)
C. Maxilla
D. Cricoid cartilage
The maxilla arises from the first pharyngeal arch.
5. A patient is found to have elevated TSH and low free T4. What is the
most likely diagnosis?
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Sick euthyroid syndrome
Elevated TSH and low free T4 indicates primary hypothyroidism.
,6. A man with schizophrenia believes the TV is sending him messages. This
is an example of which symptom?
A. Hallucination
B. Delusion of reference
C. Disorganized speech
D. Catatonia
Delusion of reference involves belief that neutral stimuli (e.g., TV) have
personal meaning.
7. Which of the following bacteria produces a toxin that inhibits protein
synthesis by inactivating EF-2?
A. Clostridium tetani
B. Bacillus anthracis
C. Corynebacterium diphtheriae
D. Bordetella pertussis
Diphtheria toxin inhibits elongation factor 2, halting protein synthesis.
8. A 72-year-old woman has hip pain and elevated alkaline phosphatase. X-
ray shows thickened trabeculae. What is the most likely diagnosis?
A. Osteoarthritis
B. Paget disease of bone
C. Osteoporosis
D. Rickets
Paget disease shows abnormal bone remodeling and high ALP with normal
calcium/phosphorus.
, 9. Which of the following drugs inhibits dihydrofolate reductase?
A. Sulfamethoxazole
B. Ciprofloxacin
C. Trimethoprim
D. Rifampin
Trimethoprim inhibits bacterial DHFR, impairing folate synthesis.
10. A patient with a renal mass and polycythemia has elevated
erythropoietin. What is the most likely tumor?
A. Transitional cell carcinoma
B. Renal cell carcinoma
C. Wilms tumor
D. Oncocytoma
RCC can produce ectopic erythropoietin, causing secondary polycythemia.
11. A 28-year-old woman has infertility and oligomenorrhea. Labs show
elevated LH/FSH ratio. What is the most likely diagnosis?
A. Endometriosis
B. Hypothyroidism
C. Polycystic ovary syndrome (PCOS)
D. Hyperprolactinemia
PCOS typically presents with oligomenorrhea, infertility, and elevated
LH/FSH ratio.
12. A patient with hypertension and hypokalemia has suppressed renin
and elevated aldosterone. What is the most likely diagnosis?
A. Renovascular hypertension
B. Primary hyperaldosteronism
