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1. At what age is routine HPV vaccination recommended to begin for
adolescents?
a) 9 years
b) 11–12 years
c) 14 years
d) 16 years
Answer: b) 11–12 years
Rationale: The CDC recommends routine HPV vaccination at ages 11–12, though it
may be started as early as 9 years.
2. A child receives the first dose of HPV vaccine at age 14. How many doses are
required for full protection?
a) One dose
b) Two doses
c) Three doses
d) Four doses
Answer: c) Three doses
Rationale: If the first dose is given at age 15 or older, a 3-dose schedule is
required.
3. If a patient begins HPV vaccination at age 12, what is the minimum time
between the first and second doses?
a) 1 month
b) 2 months
,c) 6 months
d) 12 months
Answer: c) 6 months
Rationale: For the 2-dose series, the second dose is administered 6–12 months
after the first dose.
4. A 20-year-old college student has never received an HPV vaccine. What is the
appropriate vaccination plan?
a) No vaccine is needed; it is only given up to age 18
b) Begin 2-dose HPV series
c) Begin 3-dose HPV series
d) HPV vaccine is contraindicated in adults
Answer: c) Begin 3-dose HPV series
Rationale: HPV vaccination is recommended up to age 26. Those initiating at age
≥15 require 3 doses.
5. Which HPV vaccine formulation protects against the most HPV types currently
available in the U.S.?
a) Bivalent (HPV2)
b) Quadrivalent (HPV4)
c) 9-valent (HPV9)
d) Monovalent
Answer: c) 9-valent (HPV9)
Rationale: The 9-valent vaccine (Gardasil 9) covers 9 HPV types and is the standard
in the U.S.
6. A 12-year-old receives the first HPV vaccine but misses the second dose. Two
years later, she returns at age 14. What should you do?
a) Restart the series
b) Give the second dose today; no need to restart
,c) Repeat the first dose and continue
d) Skip further doses
Answer: b) Give the second dose today; no need to restart
Rationale: The HPV vaccine series does not need to be restarted, regardless of
delay.
7. Which of the following is a contraindication to HPV vaccination?
a) Mild upper respiratory infection
b) Pregnancy
c) History of mild egg allergy
d) Family history of cervical cancer
Answer: b) Pregnancy
Rationale: HPV vaccine is not recommended during pregnancy, though no harm
has been documented.
8. A parent asks why her 11-year-old son should receive the HPV vaccine. What
is the best response?
a) It prevents acne
b) It prevents genital warts and several types of cancer
c) It boosts the immune system overall
d) It is required for high school
Answer: b) It prevents genital warts and several types of cancer
Rationale: HPV vaccination protects against cancers of the cervix, anus, penis, and
oropharynx, and against genital warts.
9. For the 3-dose HPV vaccine schedule, what is the timing for doses after the
first?
a) 1 month and 2 months later
b) 1 month and 4 months later
c) 1–2 months and 6 months later
, d) 3 months and 12 months later
Answer: c) 1–2 months and 6 months later
Rationale: The 3-dose schedule is given at 0, 1–2 months, and 6 months.
10. Which age group does the CDC recommend for catch-up HPV vaccination if
not previously immunized?
a) All females up to age 45
b) All males up to age 21, and females up to age 26
c) All adolescents up to age 30
d) Only those under 15 years
Answer: b) All males up to age 21, and females up to age 26
Rationale: Catch-up HPV vaccination is recommended for females through age 26
and for males through age 21 (or through 26 if immunocompromised or MSM).
11. At what ages should the two doses of MMR be given?
a) 6 months and 1 year
b) 12–15 months and 4–6 years
c) Birth and 6 months
d) 2 years and 7 years
Answer: b) 12–15 months and 4–6 years
Rationale: Standard MMR schedule.
12. A child is exposed to measles. How soon must MMR be given for
post-exposure prophylaxis?
a) Within 24 hours
b) Within 72 hours
c) Within 1 week
d) No benefit after exposure
Answer: b) Within 72 hours
Rationale: Early vaccination within 72 hours can prevent or reduce illness.