Nclex-Kaplan-Review review to pass nclex in one take
Pharmacology (Texas Woman's University)
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Normal Lab Values
• Hgb (hemoglobin): males=14-18 females=12-16; w/ <6.8= NC of 2L
o <12= iron deficiency anemia…… >15= dehydration, HF, or COPD
• Hct (hematocrit): males=42-52 females=37-47; ↑ of >4 points in 2 weeks= ↑ risk for
seizures
• RBC’s: males=4.7-6.1 million females=4.2-5.4 million
• WBC’s: 4,500-11,000 (4.5-11 K)
• Platelets: 1,500-400,000 (150-400 K)
• PT (Coumadin/Warfarin): 11-15 sec. (INR:2-3 & PT TR)… must be 1.5-2x’s normal
• PTT ( Heparin): 60-70 sec. (APTT: 30-40 & PTT TR)… must be 1.5-3x’s normal
• BUN: 10-20
• Creatinine: 0.5-1.2
• Specific Gravity: 1.005-1.030
• Sodium: 136-145……. <135= flat neck veins, generalized weakness, ↓ DTR’s, hyperactive
bowel sounds….>145= Cushing’s syndrome, pts w/ corticosteroids
• Potassium: 3.5-5……………..<3.5=prominent U waves, ↓ ST segment, & flat T waves…………….
>5= tall peaked T waves, prolonged PR interval & wide QRS.
• Calcium: 9-10.5………<9= muscle spasm, convulsions, cramps, tetany, + trousseau’s, +
chvostek’s, prolonged ST interval, prolonged QT interval, & wide QRS.
• Magnesium: 1.5-2.5
• Chloride: 96-106
• Phosphorus: 3-4.5 …<2.9 malnutrition/ starvation, alcoholism ……>4.5 renal insufficiency or
tumor lysis syndrome.
• Pre Albumin: 20-36 Albumin: 3.5-5 Serum Protein level: 6-8
• Dilantin TR: 10-20
• Lithium TR:1.5-1.5. >1.5= toxicity: fine tremors, nausea, drowsiness, slurred speech,
muscle weakness, diarrhea, & vomiting. ↓Na levels puts the pt @ risk for toxicity; Maintain
normal Na & fluid intake. Takes 1-4 weeks to reach therapeutic level: avoid driving until
then. NO CAFFEINE! Regular blood tests & maintain weight.
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• Digoxin TR: 0.8-2.0…..hold>2.0…..>2.5=toxic (visual disturbances: yellow halos/lights);
greater ↑ risk w/ ↓ K+. Monitor K+
• LDL: <130 HDL: >40
• Lactate level: <2.2= normal …………….>4=septic
• Bilirubin (newborn): 1-12 >15 requires phototherapy
• ASA (therapeutic anti-arthritic levels): 20-30…>30=toxic
• PSA: <4
• Amylase: 25-151… w/ acute pancreatitis is doesn’t exceed 3 x’s the normal value
• Blood urea nitrogen 8-25 is checked to see if Tx of UTI or dehydration was successful.
o <8 fluid overload >25 dehydration
Arterial Blood Gases
o pH: 7.35-7.45
o CO2 (respiratory driver): 35-45- Acidodic
o HCO3 (metabolic driver): 21-28- Alkalosis
**Compensated-pH becomes Normal **
**Partially compensated- CO2+HCO3 are BOTH ↑↓ & pH is abnormal.
** Uncompensated- ALL are abnormal**
҉ Diarrhea/DKA (fruity breathe) = Metabolic Acidosis
҉ Vomiting= Metabolic Alkalosis
҉ Hypoventilation= Respiratory Acidosis → too much CO2
҉ Hyperventilation= Respiratory Alkalosis → low CO2
Fluid & Electrolytes
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▪ Fluid Volume Deficit Fluid Volume Excess
↑hematocrit ↓ hematocrit
↓ BP ↑BP
↑ Urine specificity >1.030 ↓ urine specificity
↑ CVP (normal 4-11)
↑ BUN
o Types of solutions:
▪ Hypotonic= hydrates the cell; tap water, .45% NaCL, .33% NaCL
▪ Isotonic= stays put; D5%W, RL, NS 0.9%. *Only sterile saline for bladder
irrigation*
▪ D5W w/ KCL: should be no faster than 20 mEq/h
▪ Hypertonic= expands volume; D10%W, D5%NS, Albumin
Antidotes
⬥ Digoxin→ Digiband
⬥ Coumadin→ Vitamin K
⬥ Benzodiazepines→ Flumazenil (Tomazicon)
⬥ Mg Sulfate→ Calcium Gluconate
⬥ Heparin→ Protamine Sulfate
⬥ Tylenol→ Mucomist (17 doses + a loading dose)
⬥ Opiates (heroin/morphine)→ Narcan (Naloxone)
⬥ Cholinergic Drugs (myesthenic bradycardia)→ Atropine
⬥ Methotrexate→ Leucovorin
Pediatrics
◇ The preferred injection site for vitamin K in the newborn is the lateral aspect of
the middle third of the vastus lateralis muscle in the newborn's thigh.
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