Wound Healing, Infection, and
Integumentary System Questions –
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Layers of skin ANSW ✔✔ epidermis, dermis, hypodermis
Function of skin ANSW ✔✔ -protection
-prevents penetration
-perception
-temperature regulation
-identification
-communication
-wound repair
-absorption and excretion
-production of vitamin D
Characteristics of innate immunity ANSW ✔✔ 1. Relatively low specificity
2. Limited diversity
3. Relatively stereotypic
4. Does not generate memory
5. Recognition of self
6. First line of defense
Inflammatory response ANSW ✔✔ nonspecific defense against infection/injury,
characterized by redness, heat, swelling, and pain
Mechanisms of wound healing ANSW ✔✔ -Hemostasis (coagulation and infiltration)
, -Inflammatory (Clean wound, create scab)
-Proliferative (New tissues/capillaries forming)
-Remodeling (New skin formed)
Delayed wound healing factors ANSW ✔✔ Anemia
Hypoperfusion
Smoking
Poor diet
Not offloading pressure point
Infection
Stress
Diabetes
Obesity
Medications
Alcoholism
Development of chronic wounds ANSW ✔✔ -Repeated trauma
-Diabetes (impaired healing, neuropathy, stiffer blood vessels)
-Limited mobility
-Edema
Compare and contrast the immune systems in newborns and the elderly ANSW ✔✔ Same-
Increased risk of illness due to weaker immunity
Elderly immune systems are weaker to infection and less likely to support wound healing
Humoral immunity ANSW ✔✔ specific immunity produced by B cells that produce
antibodies that circulate in body fluids