NSG 552 PsychoPharmacology Wilkes Exam 3 Study Guide Fall
2025 question and 100% verified answers
1. First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) -
ANSWER>naltrexone and acamprosate
2. Second Line Treatments for alcohol use disorder (according to study guide but not dynamed) -
ANSWER>Disulfuram and Bupropion (not FDA approved for ETOH but second line according to
study guide)
3. Second Line Treatment for alcohol use disorder (according to Dynamed) - ANSWER>Disulfuram
4. Other off label medications for alcohol use disorder according to Dynamed -
ANSWER>Topiramate, gabapentin, baclofen
5. Other off label medications for alcohol use disorder according to Stahl's - ANSWER>Topiramate,
ondansetron
6. MOA of Naltrexone - ANSWER>Opioid Receptor Antagonist
7. MOA of Acamprosate - ANSWER>- weak GABAa agonist
- weak NMDA antagonist
8. (does not prevent withdrawal symptoms)
9. MOA of Disulfuram - ANSWER>inhibits enzyme (aldehyde dehydrogenase) in the liver
10. Bupropions role in alcohol use disorder - ANSWER>Can diminish cravings for etoh, treat
underlying anxiety/depression
11. Safety Risk associated with bupropion and etoh - ANSWER>bupropion increases the risk of
seizures in those going through etoh withdrawal
, 12. s/s ETOH intoxication - ANSWER>impaired fine motor control, impaired judgement and
coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright, difficulty with
memory and sitting upright, N/V, coma in levels 300mg/dL and over with respiratory
depression and death possible
13. S/S of etoh withdrawal - ANSWER>Mild: insomnia, irritability, hand tremor
14. Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
15. Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
16. Delirium Tremens - ANSWER>48-96 hours after last etoh consumption includes anxiety,
anorexia, nausea/vomiting, psychomotor agitation
17. Scale used to measure etoh withdrawal - ANSWER>CIWA
18. CIWA assesses: - ANSWER>n/v, tremor, paroxysmall sweats, anxiety, agitation, tactile
disturbances, auditory disturbances, visual disturbances, headaches, orientation
19. CIWA scoring - ANSWER><10=mild
20. 10-15=moderate
21. >15=severe
22. What medication is FDA approved for both opioid use disorder and alcohol use disorder? -
ANSWER>Naltrexone
23. What routes of administration exist for Naltrexone - ANSWER>PO, monthly injection (Vivitrol),
implant
24. What is the First Line medication in maintaining abstinence after alcohol detoxification? -
ANSWER>Acamprosate
25. What medication can safely be used to treat alcohol use disorder in patients who keep
drinking alcohol? - ANSWER>Acamprosate
2025 question and 100% verified answers
1. First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) -
ANSWER>naltrexone and acamprosate
2. Second Line Treatments for alcohol use disorder (according to study guide but not dynamed) -
ANSWER>Disulfuram and Bupropion (not FDA approved for ETOH but second line according to
study guide)
3. Second Line Treatment for alcohol use disorder (according to Dynamed) - ANSWER>Disulfuram
4. Other off label medications for alcohol use disorder according to Dynamed -
ANSWER>Topiramate, gabapentin, baclofen
5. Other off label medications for alcohol use disorder according to Stahl's - ANSWER>Topiramate,
ondansetron
6. MOA of Naltrexone - ANSWER>Opioid Receptor Antagonist
7. MOA of Acamprosate - ANSWER>- weak GABAa agonist
- weak NMDA antagonist
8. (does not prevent withdrawal symptoms)
9. MOA of Disulfuram - ANSWER>inhibits enzyme (aldehyde dehydrogenase) in the liver
10. Bupropions role in alcohol use disorder - ANSWER>Can diminish cravings for etoh, treat
underlying anxiety/depression
11. Safety Risk associated with bupropion and etoh - ANSWER>bupropion increases the risk of
seizures in those going through etoh withdrawal
, 12. s/s ETOH intoxication - ANSWER>impaired fine motor control, impaired judgement and
coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright, difficulty with
memory and sitting upright, N/V, coma in levels 300mg/dL and over with respiratory
depression and death possible
13. S/S of etoh withdrawal - ANSWER>Mild: insomnia, irritability, hand tremor
14. Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
15. Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
16. Delirium Tremens - ANSWER>48-96 hours after last etoh consumption includes anxiety,
anorexia, nausea/vomiting, psychomotor agitation
17. Scale used to measure etoh withdrawal - ANSWER>CIWA
18. CIWA assesses: - ANSWER>n/v, tremor, paroxysmall sweats, anxiety, agitation, tactile
disturbances, auditory disturbances, visual disturbances, headaches, orientation
19. CIWA scoring - ANSWER><10=mild
20. 10-15=moderate
21. >15=severe
22. What medication is FDA approved for both opioid use disorder and alcohol use disorder? -
ANSWER>Naltrexone
23. What routes of administration exist for Naltrexone - ANSWER>PO, monthly injection (Vivitrol),
implant
24. What is the First Line medication in maintaining abstinence after alcohol detoxification? -
ANSWER>Acamprosate
25. What medication can safely be used to treat alcohol use disorder in patients who keep
drinking alcohol? - ANSWER>Acamprosate
