Page 1 of 52
MT AAB IMMUNOLOGY EXAM WITH 350
QUESTIONS AND WELL ELABORATED ANSWERS
JUST RELEASED THIS YEAR
what is responsible for the humoral immune response:
a) B lymphocyte
b) T Lymphocyte
c ) Natural killer cell
d Mast cell
B lymphocytes.
Humoral immunity involves antibody production. Most B lymphocytes participate in the
humoral response through their transformation into plasma cells and secretion of antibodies.
Other B cells become long-lived memory cells.Neutrophils are part of cellular immunity. Their
major function is phagocytosis and destruction of foreign material and microorganisms.Basophil
granules contain histamine, and they play a vital role in allergic reactions and the inflammatory
response. Monocytes are phagocytic cells and recognize bacterial pathogens.While monocytes
do present antigens to B-lymphocytes to initiate the adaptive immune response, it is the B
lymphocyte that is responsible for the antibody production of the humoral immune response.
The immunoglobulin classe chiefly responsible for the degranulation of mast cells and
basophils?
IgA
IgE
, Page 2 of 52
IgD
IgG
IgE
this T lymphocyte expresses the CD8+ marker and acts specifically to kill tumor or virally-
infected cells?
T cytotoxic
A nonimmunogenic material capable of stimulating an immune response only when bound to
a carrier protein is termed
A hapten
myoglobin
Fc portion
determinants
A hapten
describes the relation of nephelometry to turbidimetry?
Nephelometry directly measures the amount of light scattered by particles in
solution, and turbidimetry measures the decrease in incident-light intensity
Raynaud's phenomenon is associated with a deficiency/dysfunction of the complement
fraction:
C7
tell me the part of an immunoglobulin (Ig) molecule exists as kappa or lambda chains?
Light chains
Heavy chain
Peptile bond
, Page 3 of 52
Light chains
components characterize the second line of human body defense against microbial pathogens
Phagocytic neutrophils and macrophages
The infectious disease process in which large numbers of activated macrophages and
histiocytes are collected at the site of inflammation is called?
Granulomatous
The most significant class of microbial targets for Natural Killer (NK) cells is:
Viruses
The immunoglobulin class responsible for the etiology of Hemolytic Disease of the Fetus and
Newborn (HDFN) is:
IgG
Both antibody excess (prozone) and antigen excess (postzone) result in the formation of small
antigen-antibody complexes. This results in false negative reactions because the number of
agglutinated cells are decreased.
true
section of an immunoglobulin molecule is responsible for the differences between
immunoglobulin classes?
Heavy chains
The Fc portion is responsible for the biological activity of the antibody. Depending on the class
of antibody, some of the functional activities of the Fc portion of antibodies include activating
the complement pathway and binding to natural killer cells.
true
, Page 4 of 52
Fab stands for fragment antigen binding and indicates the fragment after enzyme, papain,
cleavage. The Fab section of an immunoglobulin molecule is the antigen-specific region. It has
two light chains and portions of two heavy chains
true
The strength with which multivalent antigens and antibodies bind is best described by
Avidity
the complement component that is found in both the classical and alternative pathways?
C3
C1q
C7
C1
C3
tell me the kappa to lambda ratios are found in normal B cells?
2:1
3:1
10 : 1
20 : 1
2:1
immunoglobulin associated with anaphylactic shock?
IgG
IgA
IgM
MT AAB IMMUNOLOGY EXAM WITH 350
QUESTIONS AND WELL ELABORATED ANSWERS
JUST RELEASED THIS YEAR
what is responsible for the humoral immune response:
a) B lymphocyte
b) T Lymphocyte
c ) Natural killer cell
d Mast cell
B lymphocytes.
Humoral immunity involves antibody production. Most B lymphocytes participate in the
humoral response through their transformation into plasma cells and secretion of antibodies.
Other B cells become long-lived memory cells.Neutrophils are part of cellular immunity. Their
major function is phagocytosis and destruction of foreign material and microorganisms.Basophil
granules contain histamine, and they play a vital role in allergic reactions and the inflammatory
response. Monocytes are phagocytic cells and recognize bacterial pathogens.While monocytes
do present antigens to B-lymphocytes to initiate the adaptive immune response, it is the B
lymphocyte that is responsible for the antibody production of the humoral immune response.
The immunoglobulin classe chiefly responsible for the degranulation of mast cells and
basophils?
IgA
IgE
, Page 2 of 52
IgD
IgG
IgE
this T lymphocyte expresses the CD8+ marker and acts specifically to kill tumor or virally-
infected cells?
T cytotoxic
A nonimmunogenic material capable of stimulating an immune response only when bound to
a carrier protein is termed
A hapten
myoglobin
Fc portion
determinants
A hapten
describes the relation of nephelometry to turbidimetry?
Nephelometry directly measures the amount of light scattered by particles in
solution, and turbidimetry measures the decrease in incident-light intensity
Raynaud's phenomenon is associated with a deficiency/dysfunction of the complement
fraction:
C7
tell me the part of an immunoglobulin (Ig) molecule exists as kappa or lambda chains?
Light chains
Heavy chain
Peptile bond
, Page 3 of 52
Light chains
components characterize the second line of human body defense against microbial pathogens
Phagocytic neutrophils and macrophages
The infectious disease process in which large numbers of activated macrophages and
histiocytes are collected at the site of inflammation is called?
Granulomatous
The most significant class of microbial targets for Natural Killer (NK) cells is:
Viruses
The immunoglobulin class responsible for the etiology of Hemolytic Disease of the Fetus and
Newborn (HDFN) is:
IgG
Both antibody excess (prozone) and antigen excess (postzone) result in the formation of small
antigen-antibody complexes. This results in false negative reactions because the number of
agglutinated cells are decreased.
true
section of an immunoglobulin molecule is responsible for the differences between
immunoglobulin classes?
Heavy chains
The Fc portion is responsible for the biological activity of the antibody. Depending on the class
of antibody, some of the functional activities of the Fc portion of antibodies include activating
the complement pathway and binding to natural killer cells.
true
, Page 4 of 52
Fab stands for fragment antigen binding and indicates the fragment after enzyme, papain,
cleavage. The Fab section of an immunoglobulin molecule is the antigen-specific region. It has
two light chains and portions of two heavy chains
true
The strength with which multivalent antigens and antibodies bind is best described by
Avidity
the complement component that is found in both the classical and alternative pathways?
C3
C1q
C7
C1
C3
tell me the kappa to lambda ratios are found in normal B cells?
2:1
3:1
10 : 1
20 : 1
2:1
immunoglobulin associated with anaphylactic shock?
IgG
IgA
IgM
