ADVANCED PATHOPHYSIOLOGY EXAM 1
ADVANCED PATHOPHYSIOLOGY EXAM 1 NEWEST 2025/2026
COMPLETE 300 QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+
The 16-year-old boy has enlarged lymph nodes and a sore throat. His girlfriend
was recently diagnosed with infectious mononucleosis, which is caused by
________ and commonly transmitted in ________.
-heterophil antibodies; blood
-Epstein Barr virus; saliva
-T-cell infection; plasma
-bacterial infection; monocytes
-Epstein Barr virus; saliva
The patient is diagnosed with Hodgkin type of lymphoma based on the results of
laboratory tests and study of the tumor cells. A distinct characteristic of Hodgkin
lymphoma is the presence of:
-Reed-Sternberg cells.
-Bence Jones proteins.
-M-type protein antibodies.
-Philadelphia chromosome.
-Reed-Sternberg cells.
Manifestations of Hodgkin lymphoma that distinguish it from non-Hodgkin
lymphoma include:
-noncontiguous nodal spread.
-superficial lymphadenopathy.
-pruritus and night fevers.
-poor humoral antibody response.
-pruritus and night fevers.
Leukemias are classified according to the predominant cell type. The myelogenous
cell type of leukemia can:
1|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
-interfere with thrombocyte cell maturation.
-originate in marrow and infiltrate nodes.
-affect B and T stem cells in bone marrow.
-transform mature cells into immature ones.
-interfere with thrombocyte cell maturation.
A child has Down syndrome and has recently experienced unexplained nose
bleeds. His blood tests identify blast cells in the peripheral smear. In addition to
nose bleeds, his acute leukemia will typically manifest all of the following EXCEPT:
-infections due to neutropenia.
-fatigue due to RBC deficiency.
-hypogammaglobulinemia.
-bleeding due to thrombocytopenia.
-hypogammaglobulinemia.
In contrast to acute leukemias, chronic leukemias are malignancies involving
abnormal _________________ blood cells in the marrow.
-production of undifferentiated
-proliferation of well-differentiated
-uncontrolled growth of immature
-replication of pluripotent precursor
-proliferation of well-differentiated
Multiple myeloma is a malignancy of:
-plasma cells.
-bone osteoblasts.
-T-cell lymphocytes.
-immunoglobulin A.
-plasma cells.
A 16-year-old girl has been brought to her primary care provider by her mother
due to the daughter's recent malaise and lethargy. Which of the following
assessments should the clinician perform in an effort to confirm or rule out
2|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
infectious mononucleosis?
-Auscultating the patient's lungs
-Palpating the patient's lymph nodes
-Assessing the patient's cranial nerve reflexes
-Assessing the patient for bone pain
-Palpating the patient's lymph nodes
Following peripheral blood testing and a bone marrow biopsy, a patient has been
diagnosed with chronic myelogenous leukemia. Which of the following is most
likely to have preceded the patient's diagnosis?
-The presence of a Philadelphia chromosome
-Down syndrome
-Radiation exposure
-Exposure to the Epstein-Barr virus
-The presence of a Philadelphia chromosome
A patient has been diagnosed with non-Hodgkin lymphoma (NHL), a form of
malignancy that most likely originated in which of the following sites?
-Thymus
-Spleen
-Bone marrow
-Lymph nodes
-Lymph nodes
A young adult is preparing to begin treatment for non-Hodgkin lymphoma (NHL), a
disease that has disseminated widely. What is the most likely treatment regimen
for this patient?
-Antiviral medications
-Surgery and whole blood transfusion
-Radiation and chemotherapy
-Bone marrow or stem cell transplantation
-Radiation and chemotherapy
3|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
To form a platelet plug, platelets are attracted to the damaged vessel, and then
platelet ___________ occurs.
-adhesion
-fibrinolysis
-thrombosis
-thromboxane A2
-adhesion
Increased platelet function, and consequent hypercoagulability, can be caused by:
-factor V mutation.
-platelet insensitivity.
-vascular wall damage.
-decreased platelet numbers.
-vascular wall damage.
Immune thrombocytopenia purpura (ITP) is a/an ________ disorder that destroys
________.
-allergic; fibrinogen
-alloimmune; factor VIII
-autoimmune; platelets
-immunoglobulin; B cells
-autoimmune; platelets
Thrombotic thrombocytopenic purpura (TTP) causes which of the following
manifestations? Select all that apply.
-Purpura
-Jaundice
-Petechiae
-Erythema
-Confusion
4|Page
ADVANCED PATHOPHYSIOLOGY EXAM 1 NEWEST 2025/2026
COMPLETE 300 QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+
The 16-year-old boy has enlarged lymph nodes and a sore throat. His girlfriend
was recently diagnosed with infectious mononucleosis, which is caused by
________ and commonly transmitted in ________.
-heterophil antibodies; blood
-Epstein Barr virus; saliva
-T-cell infection; plasma
-bacterial infection; monocytes
-Epstein Barr virus; saliva
The patient is diagnosed with Hodgkin type of lymphoma based on the results of
laboratory tests and study of the tumor cells. A distinct characteristic of Hodgkin
lymphoma is the presence of:
-Reed-Sternberg cells.
-Bence Jones proteins.
-M-type protein antibodies.
-Philadelphia chromosome.
-Reed-Sternberg cells.
Manifestations of Hodgkin lymphoma that distinguish it from non-Hodgkin
lymphoma include:
-noncontiguous nodal spread.
-superficial lymphadenopathy.
-pruritus and night fevers.
-poor humoral antibody response.
-pruritus and night fevers.
Leukemias are classified according to the predominant cell type. The myelogenous
cell type of leukemia can:
1|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
-interfere with thrombocyte cell maturation.
-originate in marrow and infiltrate nodes.
-affect B and T stem cells in bone marrow.
-transform mature cells into immature ones.
-interfere with thrombocyte cell maturation.
A child has Down syndrome and has recently experienced unexplained nose
bleeds. His blood tests identify blast cells in the peripheral smear. In addition to
nose bleeds, his acute leukemia will typically manifest all of the following EXCEPT:
-infections due to neutropenia.
-fatigue due to RBC deficiency.
-hypogammaglobulinemia.
-bleeding due to thrombocytopenia.
-hypogammaglobulinemia.
In contrast to acute leukemias, chronic leukemias are malignancies involving
abnormal _________________ blood cells in the marrow.
-production of undifferentiated
-proliferation of well-differentiated
-uncontrolled growth of immature
-replication of pluripotent precursor
-proliferation of well-differentiated
Multiple myeloma is a malignancy of:
-plasma cells.
-bone osteoblasts.
-T-cell lymphocytes.
-immunoglobulin A.
-plasma cells.
A 16-year-old girl has been brought to her primary care provider by her mother
due to the daughter's recent malaise and lethargy. Which of the following
assessments should the clinician perform in an effort to confirm or rule out
2|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
infectious mononucleosis?
-Auscultating the patient's lungs
-Palpating the patient's lymph nodes
-Assessing the patient's cranial nerve reflexes
-Assessing the patient for bone pain
-Palpating the patient's lymph nodes
Following peripheral blood testing and a bone marrow biopsy, a patient has been
diagnosed with chronic myelogenous leukemia. Which of the following is most
likely to have preceded the patient's diagnosis?
-The presence of a Philadelphia chromosome
-Down syndrome
-Radiation exposure
-Exposure to the Epstein-Barr virus
-The presence of a Philadelphia chromosome
A patient has been diagnosed with non-Hodgkin lymphoma (NHL), a form of
malignancy that most likely originated in which of the following sites?
-Thymus
-Spleen
-Bone marrow
-Lymph nodes
-Lymph nodes
A young adult is preparing to begin treatment for non-Hodgkin lymphoma (NHL), a
disease that has disseminated widely. What is the most likely treatment regimen
for this patient?
-Antiviral medications
-Surgery and whole blood transfusion
-Radiation and chemotherapy
-Bone marrow or stem cell transplantation
-Radiation and chemotherapy
3|Page
, ADVANCED PATHOPHYSIOLOGY EXAM 1
To form a platelet plug, platelets are attracted to the damaged vessel, and then
platelet ___________ occurs.
-adhesion
-fibrinolysis
-thrombosis
-thromboxane A2
-adhesion
Increased platelet function, and consequent hypercoagulability, can be caused by:
-factor V mutation.
-platelet insensitivity.
-vascular wall damage.
-decreased platelet numbers.
-vascular wall damage.
Immune thrombocytopenia purpura (ITP) is a/an ________ disorder that destroys
________.
-allergic; fibrinogen
-alloimmune; factor VIII
-autoimmune; platelets
-immunoglobulin; B cells
-autoimmune; platelets
Thrombotic thrombocytopenic purpura (TTP) causes which of the following
manifestations? Select all that apply.
-Purpura
-Jaundice
-Petechiae
-Erythema
-Confusion
4|Page
