Advanced Pharmacology Guide| Questions & Answers|
Grade A| 100% Correct (Verified Solutions)- Wilkes
symptoms of uncontrolled asthma - correct answersat least three of the following:
-daytime asthma more than 2x a week
-nighttime awakening
-reliever therapy more than 2x a week
-activity intolerance
treatment of asthma symptoms less than 2x a month - correct answersas needed low
dose ICS-formoterol or as needed low dose ICS with SABA
treatment of asthma symptoms more than 2x a month - correct answersdaily low dose
ICS and as needed SABA or as needed low dose ICS-formoterol
treatment of asthma symptoms most days of the week - correct answersdaily low dose
ICS-formoterol and as needed SABA or daily medium dose ICS and SABA
treatment of daily asthma symptoms (severe asthma) - correct answersdaily medium
dose ICS-formoterol with reliever therpy OR daily high dose ICS with reliever therapy
ICS-formoterol medication drug name - correct answersbudesonide-formoterol
Short-acting muscarinic antagonist (SAMA) - correct answersIpratropium
avoid co administration of ICS with which CYP3A4 inhibitors? (may cause cushing's) -
correct answersritonavir, itraconazole, ketoconazole
lack of response to ICS may be indicative of what? - correct answersCLCCl1 gene
LABAs - correct answersSalmeterol
Formoterol
Vilanterol
LAMAs - correct answerstiotropium bromide
umeclidinium
lueokotriene receptor antagonists - correct answers-lukast
, monoclonal antibodies - correct answers-umab, monitor for adverse events 2 hours
afterwards for 3 months and then 30 minutes afterwards therafter, co-prescribe with
epipen
contraindications for theophylline (methylxanthine) - correct answerspulmonary edema,
hypothyroidism, liver disease, renal dysfunction, recent smoking cessation, pregnancy,
antifungal agents, carbamazepine, rifampin, etc.
which beta blockers are contraindicated in asthma - correct answersnadolol,
propranolol, timolol, sotaolol
COPD classification A (few symptoms, low exposure risk) - correct answersSABA
COPD classification B (more symptoms, low exacerbation risk) - correct answersLABA
or LAMA
COPD classification C (few symptoms, high exacerbation risk) - correct answersLAMA
COPD classification D (more symptoms, high exacerbation risk) - correct answersLAMA
or LAMA+LABA or ICS-LABA
Roflumilast - correct answersphosphodiesterase-4 inhibitor, may cause weight loss,
diarrhea, and depression
Intranasal decongestants - correct answersoxymetazoline, phenylephrine, naphazoline
avoid intranasal decongestants with these conditions - correct answersBPH, glaucoma,
cardiac disease, hyperthyroidism
Intranasal Cromolyn - correct answersNasalCrom
Extremely safe but moderately effective
Suppresses release of histamines from mast cells
Best used for prophylaxis, not treatment
Response may take 1-2 wks to develop
how to treat hypertension - correct answersa. Step 1: ACE inhibitor or ARB or CCB or
thiazide diuretic
b. Step 2: ACE inhibitor or ARB + CCB or thiazide diuretic
c. Step 3: ACE inhibitor or ARB + CCB + thiazide diuretic
Step 4: ACE inhibitor or ARB + CCB + thiazide diuretic + spironolactone
Avoid CCB in patients with - correct answersheart failure or MI
avoid ARBs in patients with - correct answersMI, pregnancy
Calcium Channel Blockers - correct answers-dipine (dihydropyridine)