Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
1. A client who received a prescription for cy- c. Allow a 15-minute interval be-
closporine ophthalmic emulsion for dry eyes tween the administration of cy-
asks the practical nurse (PN) if it is safe to con- closporine and artificial tears.
tinue using artificial tears. What information Rationale:
should the PN provide? Cyclosporine, an ophthalmic emul-
a. Avoid the use of artificial tears because they sion which increases tear produc-
decrease the efficacy of cyclosporine. tion, may be used in conjunction
b. Discontinue the use of both products if tran- with artificial tears as long as the
sient blurring occurs after administration. products are administered 15 min-
c. Allow a 15-minute interval between the ad- utes apart. Transient blurring after
ministration of cyclosporine and artificial tears. administration is a side effect of cy-
d. Discontinue the use of cyclosporine and arti- closporine and does not necessitate
ficial tears when tear production reaches a nor- discontinuation of the medication.
mal level. After tear production is increased,
artificial tears may be stopped, but
discontinuing cyclosporine will result
in a decrease in tear production.
2. A first-day postoperative client vomits 30 min- b. Administer a prn dose of on-
utes after receiving a dose of hydromorphone. dansetron.
What initial intervention is best for the practical Rationale:
nurse (PN) to implement? Because the emesis appears to be
a. Obtain a prescription for nasogastric intuba- directly related to the administra-
tion. tion of the opiate analgesic, the
b. Administer a prn dose of ondansetron. first action should be to reduce the
c. Reduce the next scheduled dose of hydromor- client's nausea with the administra-
phone. tion of the ondansetron, which is an
d. Assess the client's abdomen and bowel antiemetic.
sounds.
3.
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
A client has been prescribed losartan. Which d. Blood pressure reduced from
change in data indicates to the practical nurse 160/90 to 130/80 mm Hg.
(PN) that the desired effect of this medication Rationale:
has been achieved? Losartan is prescribed for the treat-
a. Dependent edema reduced from +3 to +1. ment of hypertension. The desired
b. Serum HDL increased from 35 to 55 mg/dL. effect is a decrease in blood pres-
c. Pulse rate reduced from 150 to 90 beats/min. sure.
d. Blood pressure reduced from 160/90 to
130/80 mm Hg.
4. A child is admitted to the emergency depart- c. A 16 month old who drank 2
ment for accidental ingestion of a poison. The ounces of acetaminophen elixir
practical nurse (PN) should know that inducing Rationale:
vomiting is recommended for which child? Emesis should be induced for the
a. An 8 month old who ate four to six ibuprofen child who drank the large dose of
tablets acetaminophen elixir because this
b. A 3 year old who drank an unknown amount medication is hepatotoxic. Vomit-
of charcoal lighter fluid ing is contraindicated for children
c. A 16 month old who drank 2 ounces of aceta- younger than 1 year of age. Inducing
minophen elixir vomiting of corrosives such as dish-
d. A 2 year old who ate a handful of automatic washer detergents and lighter fluid
dishwasher detergent is contraindicated.
5. A practical nurse (PN) is reviewing teaching with c. The benztropine is used to control
the client and/or significant others about the the side effects of olanzapine.
concurrent use of benztropine and olanzapine Rationale:
to manage psychotic behavior. What informa- Benztropine, an anticholinergic
tion should the PN reinforce? drug, is used to control extrapyrami-
a. Benztropine will reduce the olanzapine's side dal symptoms associated with olan-
effect of urinary retention. zapine use. Caution is required in the
b. Benztropine potentiates the effect of olanza-
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
pine. dosage of benztropine used in con-
c. The benztropine is used to control the side junction with olanzapine.
effects of olanzapine.
d. The combined effect of these drugs will mod-
ify psychotic behavior.
6. A client diagnosed with a herniated disc c. Administer analgesia as requested
is prescribed hydrocodone/acetaminophen 10 by the client.
mg/300 mg prn every 4 to 6 hours. As the prac- Rationale:
tical nurse (PN) enters the client's room to ad- The medication should be admin-
minister their requested medication, the client istered as per client's request. The
is seen talking and laughing with his visiting client's self-report of pain is the sin-
family. Which action should the PN implement? gle most reliable indication of the
a. Hold the pain medication until after the visi- existence, character, and intensity of
tors leave. pain. Analgesics should be admin-
b. Notify the health care provider of the client's istered as soon as pain occurs and
drug-seeking behavior. before it increases in intensity. The
c. Administer analgesia as requested by the PN should consult with the charge
client. nurse after administering the med-
d. Inform the client based on their display be- ication about the situation.
havior, the medication is not needed.
7. The nurse is assisting with evaluating the effec- d. "I do not notice as many irregular
tiveness of the drug amiodarone. Which client heartbeats as before I started taking
statement best indicates the drug has been ef- this medication."
fective? Rationale:
a. "I have not had as many spells of angina." Amiodarone is the first choice drugs
b. "I have not had as much swelling in my ankles to treat ventricular dysrhythmias. It
lately." will not reduce angina spells, reduce
c. "My doctor told me my cholesterol levels were ankle swelling, or improve choles-
getting better every visit." terol levels.
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
d. "I do not notice as many irregular heartbeats
as before I started taking this medication."
8. A client who is prescribed sildenafil for pul- a. The client is experiencing vision
monary hypertension calls the clinic for advice. and hearing loss.
Which condition should the practical nurse noti- Rationale:
fy the health care provider immediately and in- The client should be instructed to
struct the client to stop taking the medication? discontinue the use of the med-
a. The client is experiencing vision and hearing ication and notify the health care
loss. provider immediately if the client is
b. The client has an erection lasting longer than experiencing vision and/or hearing
2 hours. loss or an erection lasting more than
c. The client is complaining about nasal conges- 4 hours.
tion.
d. The client is complaining about feeling
flushed.
9. A client is receiving heparin to treat a deep vein c. Partial thromboplastin time
thrombosis. The nurse should monitor which Rationale:
laboratory result to assist in evaluating the effi- The nurse should monitor the par-
cacy of the drug? tial thromboplastin time to evaluate
a. Platelet count the efficacy of heparin. The platelet
b. Prothrombin time count does not monitor heparin effi-
c. Partial thromboplastin time cacy. A client who is taking warfarin
d. Serum levels of protamine sulfate should have the prothrombin time
monitored. Protamine sulfate levels
do not monitor efficacy of heparin.
10. A client who is being discharged to home d. Ask him to describe the location
asks the practical nurse (PN) for a dose of hy- and severity of the pain and to rate
drocodone before leaving the hospital. How it on a scale from 1 to 10.
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
1. A client who received a prescription for cy- c. Allow a 15-minute interval be-
closporine ophthalmic emulsion for dry eyes tween the administration of cy-
asks the practical nurse (PN) if it is safe to con- closporine and artificial tears.
tinue using artificial tears. What information Rationale:
should the PN provide? Cyclosporine, an ophthalmic emul-
a. Avoid the use of artificial tears because they sion which increases tear produc-
decrease the efficacy of cyclosporine. tion, may be used in conjunction
b. Discontinue the use of both products if tran- with artificial tears as long as the
sient blurring occurs after administration. products are administered 15 min-
c. Allow a 15-minute interval between the ad- utes apart. Transient blurring after
ministration of cyclosporine and artificial tears. administration is a side effect of cy-
d. Discontinue the use of cyclosporine and arti- closporine and does not necessitate
ficial tears when tear production reaches a nor- discontinuation of the medication.
mal level. After tear production is increased,
artificial tears may be stopped, but
discontinuing cyclosporine will result
in a decrease in tear production.
2. A first-day postoperative client vomits 30 min- b. Administer a prn dose of on-
utes after receiving a dose of hydromorphone. dansetron.
What initial intervention is best for the practical Rationale:
nurse (PN) to implement? Because the emesis appears to be
a. Obtain a prescription for nasogastric intuba- directly related to the administra-
tion. tion of the opiate analgesic, the
b. Administer a prn dose of ondansetron. first action should be to reduce the
c. Reduce the next scheduled dose of hydromor- client's nausea with the administra-
phone. tion of the ondansetron, which is an
d. Assess the client's abdomen and bowel antiemetic.
sounds.
3.
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
A client has been prescribed losartan. Which d. Blood pressure reduced from
change in data indicates to the practical nurse 160/90 to 130/80 mm Hg.
(PN) that the desired effect of this medication Rationale:
has been achieved? Losartan is prescribed for the treat-
a. Dependent edema reduced from +3 to +1. ment of hypertension. The desired
b. Serum HDL increased from 35 to 55 mg/dL. effect is a decrease in blood pres-
c. Pulse rate reduced from 150 to 90 beats/min. sure.
d. Blood pressure reduced from 160/90 to
130/80 mm Hg.
4. A child is admitted to the emergency depart- c. A 16 month old who drank 2
ment for accidental ingestion of a poison. The ounces of acetaminophen elixir
practical nurse (PN) should know that inducing Rationale:
vomiting is recommended for which child? Emesis should be induced for the
a. An 8 month old who ate four to six ibuprofen child who drank the large dose of
tablets acetaminophen elixir because this
b. A 3 year old who drank an unknown amount medication is hepatotoxic. Vomit-
of charcoal lighter fluid ing is contraindicated for children
c. A 16 month old who drank 2 ounces of aceta- younger than 1 year of age. Inducing
minophen elixir vomiting of corrosives such as dish-
d. A 2 year old who ate a handful of automatic washer detergents and lighter fluid
dishwasher detergent is contraindicated.
5. A practical nurse (PN) is reviewing teaching with c. The benztropine is used to control
the client and/or significant others about the the side effects of olanzapine.
concurrent use of benztropine and olanzapine Rationale:
to manage psychotic behavior. What informa- Benztropine, an anticholinergic
tion should the PN reinforce? drug, is used to control extrapyrami-
a. Benztropine will reduce the olanzapine's side dal symptoms associated with olan-
effect of urinary retention. zapine use. Caution is required in the
b. Benztropine potentiates the effect of olanza-
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
pine. dosage of benztropine used in con-
c. The benztropine is used to control the side junction with olanzapine.
effects of olanzapine.
d. The combined effect of these drugs will mod-
ify psychotic behavior.
6. A client diagnosed with a herniated disc c. Administer analgesia as requested
is prescribed hydrocodone/acetaminophen 10 by the client.
mg/300 mg prn every 4 to 6 hours. As the prac- Rationale:
tical nurse (PN) enters the client's room to ad- The medication should be admin-
minister their requested medication, the client istered as per client's request. The
is seen talking and laughing with his visiting client's self-report of pain is the sin-
family. Which action should the PN implement? gle most reliable indication of the
a. Hold the pain medication until after the visi- existence, character, and intensity of
tors leave. pain. Analgesics should be admin-
b. Notify the health care provider of the client's istered as soon as pain occurs and
drug-seeking behavior. before it increases in intensity. The
c. Administer analgesia as requested by the PN should consult with the charge
client. nurse after administering the med-
d. Inform the client based on their display be- ication about the situation.
havior, the medication is not needed.
7. The nurse is assisting with evaluating the effec- d. "I do not notice as many irregular
tiveness of the drug amiodarone. Which client heartbeats as before I started taking
statement best indicates the drug has been ef- this medication."
fective? Rationale:
a. "I have not had as many spells of angina." Amiodarone is the first choice drugs
b. "I have not had as much swelling in my ankles to treat ventricular dysrhythmias. It
lately." will not reduce angina spells, reduce
c. "My doctor told me my cholesterol levels were ankle swelling, or improve choles-
getting better every visit." terol levels.
, Pharmacology HESI Comprehensive Review for the NCLEX-PN Exam, 6th
Edition Study Mode
Study online at https://quizlet.com/_b69nhn
d. "I do not notice as many irregular heartbeats
as before I started taking this medication."
8. A client who is prescribed sildenafil for pul- a. The client is experiencing vision
monary hypertension calls the clinic for advice. and hearing loss.
Which condition should the practical nurse noti- Rationale:
fy the health care provider immediately and in- The client should be instructed to
struct the client to stop taking the medication? discontinue the use of the med-
a. The client is experiencing vision and hearing ication and notify the health care
loss. provider immediately if the client is
b. The client has an erection lasting longer than experiencing vision and/or hearing
2 hours. loss or an erection lasting more than
c. The client is complaining about nasal conges- 4 hours.
tion.
d. The client is complaining about feeling
flushed.
9. A client is receiving heparin to treat a deep vein c. Partial thromboplastin time
thrombosis. The nurse should monitor which Rationale:
laboratory result to assist in evaluating the effi- The nurse should monitor the par-
cacy of the drug? tial thromboplastin time to evaluate
a. Platelet count the efficacy of heparin. The platelet
b. Prothrombin time count does not monitor heparin effi-
c. Partial thromboplastin time cacy. A client who is taking warfarin
d. Serum levels of protamine sulfate should have the prothrombin time
monitored. Protamine sulfate levels
do not monitor efficacy of heparin.
10. A client who is being discharged to home d. Ask him to describe the location
asks the practical nurse (PN) for a dose of hy- and severity of the pain and to rate
drocodone before leaving the hospital. How it on a scale from 1 to 10.
