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Medical-Surgical Nursing Final Exam: 150 NCLEX & HESI Questions with Detailed Verified Rationales – 2025 Guaranteed Pass Edition"

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Prepare for success with this complete Medical-Surgical Nursing Final Exam study pack. Includes 150 NCLEX & HESI-style questions updated for 2025, each with detailed, verified rationales to ensure full understanding. Covers all major Med-Surg topics, aligns with the latest NCLEX test plan, and is designed for guaranteed pass confidence. Perfect for nursing students, HESI prep, and final exam review."

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Medical-Surgical Nursing Final Exam: 150 NCLEX &

HESI Questions with Detailed Verified Rationales –

2025 Guaranteed Pass Edition"




Q1. A 68-year-old man with COPD presents with increased shortness of breath and

purulent sputum. His RR is 28/min, SpO₂ is 88% on room air. Which initial

nursing action is most appropriate?

A. Encourage deep-breathing and coughing exercises and continue to monitor.

B. Administer prescribed low-flow oxygen via nasal cannula and reassess.

C. Place the patient in Trendelenburg position to improve ventilation.

D. Immediately prepare the patient for endotracheal intubation.

Correct Answer: B

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Rationale: In a COPD patient who is hypoxemic, the priority intervention is to

administer supplemental oxygen at a low flow rate, typically 1–2 L/min via nasal

cannula, to improve oxygen saturation while avoiding suppression of the hypoxic

drive to breathe. While coughing and deep-breathing exercises can help mobilize

secretions, they do not address the immediate problem of low oxygen levels.

Placing the patient in the Trendelenburg position would impair diaphragmatic

movement and reduce ventilation, worsening respiratory distress. Endotracheal

intubation is only indicated if oxygen therapy fails or the patient shows signs of

severe respiratory failure. Therefore, giving low-flow oxygen and reassessing is the

safest and most effective initial action.




Q2. A 55-year-old woman is admitted with acute chest pain. ECG shows ST-

elevation in leads II, III, and aVF. Which artery is most likely occluded?

A. Left anterior descending (LAD)

B. Right coronary artery (RCA)

C. Left circumflex artery (LCx)

D. Posterior descending artery (PDA)

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Correct Answer: B

Rationale: ST-elevation in leads II, III, and aVF indicates an inferior wall

myocardial infarction, which is most commonly caused by occlusion of the right

coronary artery (RCA). The LAD typically causes anterior wall changes (V1–V4)

and the LCx produces lateral changes (I, aVL, V5–V6). The posterior descending

artery may be involved but in many patients it branches from the RCA; the classic

lead pattern for an inferior MI points to the RCA as the likely culprit.




Q3. A client with heart failure has peripheral edema, bibasilar crackles, jugular

venous distention, and is on furosemide. Which lab should the nurse monitor most

closely?

A. Platelet count

B. Serum potassium

C. Hemoglobin

D. Serum creatinine

Correct Answer: B

Rationale: Loop diuretics like furosemide commonly cause potassium loss, risking

hypokalemia which can precipitate arrhythmias and muscle weakness; therefore

serum potassium requires close monitoring. While serum creatinine is also

important because diuretics can affect renal function, potassium is typically the

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immediate priority to prevent life-threatening cardiac effects. Platelet count and

hemoglobin are less directly affected by furosemide.




Q4. A postoperative client reports sudden onset of chest pain, dyspnea, and anxiety

on postoperative day 2. Oxygen saturation falls to 86% and there is unilateral

pleuritic chest pain. What is the most likely diagnosis?

A. Atelectasis

B. Pulmonary embolism

C. Pneumonia

D. Myocardial infarction

Correct Answer: B

Rationale: Sudden dyspnea, hypoxemia, pleuritic chest pain, anxiety, and timing

(postoperative period) strongly suggest pulmonary embolism due to

thromboembolism. Atelectasis typically causes low-grade hypoxia and gradual

symptoms, pneumonia develops more gradually with fever and productive cough,

and myocardial infarction usually presents with central chest pain and ECG

changes rather than acute isolated hypoxemia and pleuritic pain.

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