Parasitology Exam 4 Content

FINAL EXAM

Plasmodium Form and Function


-Sporozoite : daughter cell resulting from sporogony
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·
* INFECTIONS STAGE *

easter


- Trophozoite : ac tive
, feeding stase of protozoon ,
in contrast to cyst
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of aseeal reproduc tion in which multiple mitoses followed
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Schizogory : Form occur ,

- - i s


6 y Simultaneous cytokiness resulting in
many daughter cells a + once
,
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occured
shagony NOT
-s crizon t : in when nuclear divisions h ave out
,
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< y to kines : S
-



-
Merozoite : daughter call
resulting f ro m Schizogony
i s -




Plas mo diid a l


-Gametogony : process by w h i ch gometes a re produced in
protozoa
- e -
~
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merozoites &BC transforma into gametocytes
entering
· o c c u rs when

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·
macrogametocete (IF) : cell give rise to a crogamete
~

-


·
microgametocate d M) : Call give rise to
microgamete
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Microsome +e
· * for +il : 2es Macrogame + e #
-
- -



8 D o k i n e te : motile ,
elongated zygote
-
-




-sporogony : Multiple fission of a
zygote
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·
begins begins to develop
sporogonous prase when o o k i m a te
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form
: c ys i c
resulting f ro m s p o ro g o ny
·
o o d yst
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↳ * gives ris e to Many Sporozoites *

e a



Plasmodium Spo . Life Cycle

-


Genus = prosmodium (has many species
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m o s q u i to bites infected human it
ingests contain either
&7
-w h e n that
,




~ cle or female some to cates
-s e e m




·* male *
microgametodate
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O *
Macrogametocyte Female
- -




mosavito's
-
Inside the

-
set
2
(M) under go a
process called ex flagellation
-
1) -
Microgametocyte
- ~
-



w h e re it produces 8 motile microgamates (think of t h ow l i ke soorm)
-
c a t e
~


go mete
21 CFL
summe
m a c ro
- -
Macrogametocyte M a t u re s into a

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l i ke on egg) ,
No division I just one
-




-
Detailed Life (1e Steps =




~

, -
1 Fertilization = (In Mosquito !!! 3
-



& we
· of the eight microsemates fer tilizes the macroscuete



&
This fo r m s a zygote which elongates into on oo kinete and
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p e n e t r a te mosavito's get
-


ro u n d s
·
up and transfor ms to oolst rhich produces n u m e ro -s
-




~ a ploid sporozoites : sporogony
s e e
-


s p o rozo i te s wo n d e r m o s av i to slands infec t
to salivary ready to
·



- -



a new human via blood med
-


Fertilization - - Sporozoites *
-
* =
zygote Ok : nete pocyst +
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- 2 Sporozoites i nva d e l i ve r cells (ecrenchymal cells = (IN HUMAN
-


·
after m o s q u i to bite sporoboites enter b l o o d st re am and
,

-

+ - v e1 + 01 : ve r

-




medtiplication
exocryamiotic sanizosor
namental
·
u n d e rs o :




in l i ve r dolls outside RBC 4 # i + os is *
Specifically ~

-
-



&
Each infected l i ve r ce ll d eve l o p s into a s c h i zo r t : a cell filled
-


i parasites
demons
~
mons



·
Schizoat depirdes and releasing m a ny tiny merozoites into b l o o d st re a m
- i s - item

-
3 werokoites infec t RBC's ( INnvmAr)
-


·
these werozoites l e ave l i ve r and i nvo d o RBC
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R & C o c c u rs : RB
F-s: de cr ythrocytic Schizogony :
-
·

, -



obdruptures m o re merozoites blood
·
, releasing into

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orozoites Ob C Cycle
· These no w ~ : - fe c t m o re
repecting
-



·
This process causes the symptoms of molaria < Fever/ch:lls) oc

- -



response
trimminent
destruction ~ eleases substances that immune
RB)
-

- Gametocyte Formation = (IN Human
-


Il RB [
·
Af te r patient becomes Clinically :
Some ~ e rozo i te s ins: de

- ↓ -



continuing
of Schizo
develop into gametocytes instead gony
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·
scretocytes : S ex u a l forms of parasite
-




·
gametoytes circulate in Bloodstream wi + n & &C
- - -


-
5 mosquito in gests sametocytes =
(In Mosquito !!! )
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--e- -- Anopheles mosanito b i te s on infec ted person ,
it ingests
- -



blood
containing scmetocytes
-



Inside m o s q u i to gut
minocytes
· < gametes in a process
,
-


: Star ts in Human but doesn't fin is h in Human
called : gametogony -
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(fertilization) forming
wh Sexually zysote e
c

Ses fuse
·

- -