Nur 600 - Exam 1 Questions and
Answers A+ Graded (2025)
Nurse .practitioner .prescriptive .authority .is .regulated .by:
A. .The .National .Council .of .State .Boards .of .Nursing
B. .The .U.S. .Drug .Enforcement .Administration
C. .The .State .Board .of .Nursing .for .each .state
D. .The .State .Board .of .Pharmacy .- .CORRECT .ANSWER-C. .The .State .Board .of
.Nursing .for .each .state
Physician .Assistant .(PA) .prescriptive .authority .is .regulated .by:
A. .The .National .Council .of .State .Boards .of .Nursing
B. .The .U.S. .Drug .Enforcement .Administration
C. .The .State .Board .of .Nursing
D. .The .State .Board .of .Medical .Examiners .- .CORRECT .ANSWER-D. .The .State
.Board .of .Medical .Examiners
Clinical .judgment .in .prescribing .includes: .
A. .Factoring .in .the .cost .to .the .patient .of .the .medication .prescribed .
B. .Always .prescribing .the .newest .medication .available .for .the .disease .process
.C. .Handing .out .drug .samples .to .poor .patients .
D. .Prescribing .all .generic .medications .to .cut .costs .- .CORRECT .ANSWER-A.
.Factoring .in .the .cost .to .the .patient .of .the .medication .prescribed
Criteria .for .choosing .an .effective .drug .for .a .disorder .include:
A. .Asking .the .patient .what .drug .they .think .would .work .best .for .them .
B. .Consulting .nationally .recognized .guidelines .for .disease .management
C. .Prescribing .medications .that .are .available .as .samples .before .writing .a
.prescription .
D. .Following .U.S. .Drug .Enforcement .Administration .(DEA) .guidelines .for
.prescribing .- .CORRECT .ANSWER-B. .Consulting .nationally .recognized
.guidelines .for .disease .management
Nurse .practitioner .practice .may .thrive .under .health-care .reform .due .to:
A. .The .demonstrated .ability .of .nurse .practitioners .to .control .costs .and .improve
.patient .outcomes .
B. .The .fact .that .nurse .practitioners .will .be .able .to .practice .independently .
C. .The .fact .that .nurse .practitioners .will .have .full .reimbursement .under .health-
care .reform .
,D. .The .ability .to .shift .accountability .for .Medicaid .to .the .state .level .- .CORRECT
.ANSWER-A. .The .demonstrated .ability .of .nurse .practitioners .to .control .costs .and
.improve .patient .outcomes
A .patient's .nutritional .intake .and .lab .work .reflects .hypoalbuminemia. .This .is
.critical .to .prescribing .because: .
A. .Distribution .of .drugs .to .target .tissue .may .be .affected .
B. .The .solubility .of .the .drug .will .not .match .the .site .of .absorption .
C. .There .will .be .less .free .drug .available .to .generate .an .effect .
D. .Drugs .bound .to .albumin .are .readily .excreted .by .the .kidney .- .CORRECT
.ANSWER-A. .Distribution .of .drugs .to .target .tissue .may .be .affected
Drugs .that .have .a .significant .first-pass .effect: .A. .Must .be .given .by .the .enteral
.(oral) .route .only .
B. .Bypass .the .hepatic .circulation .
C. .Are .rapidly .metabolized .by .the .liver .and .may .have .little .if .any .desired .action .
D. .Are .converted .by .the .liver .to .more .active .and .fat-soluble .forms .- .CORRECT
.ANSWER-C. . Are .rapidly .metabolized .by .the .liver .and . may . have .little .if .any
.desired .action
The .route .of .excretion .of .a .volatile .drug .will .likely .be: .
A. .The .kidneys .
B. .The .lungs .
C. .The .bile .and .feces .
D. .The .skin .- .CORRECT .ANSWER-B. .The .lungs
Medroxyprogesterone .(Depo .Provera) .is .prescribed .IM .to .create .a .storage
.reservoir .of .the .drug. .Storage .reservoirs: .
A. .Assure .that .the .drug .will .reach .its .intended .target .tissue .
B. .Are .the .reason .for .giving .loading .doses .
C. .Increase .the .length .of .time .a .drug .is .available .and .active .
D. .Are .most .common .in .collagen .tissues .- .CORRECT .ANSWER-C. .Increase .the
.length .of .time .a .drug .is .available .and .active
The .NP .chooses .to .give .cephalexin .every .8 .hours .based .on .knowledge .of .the
.drug's: .
A. .Propensity .to .go .to .the .target .receptor .
B. .Biological .half-life .
C. .Pharmacodynamics .
D. .Safety .and .side .effects .- .CORRECT .ANSWER-B. .Biological .half-life
Azithromycin .dosing .requires .the .first .day's .dose .be .twice .those .of .the .other .4
.days .of .the .prescription. .This .is .considered .a .loading .dose. .A .loading .dose: .A.
.Rapidly .achieves .drug .levels .in .the .therapeutic .range .
B. .Requires .four .to .five .half-lives .to .attain .
C. .Is .influenced .by .renal .function .
D. .Is .directly .related .to .the .drug .circulating .to .the .target .tissues .- .CORRECT
.ANSWER-A. .Rapidly .achieves .drug .levels . in .the .therapeutic .range
, The .point .in .time .on .the .drug .concentration .curve .that .indicates .the .first .sign .of
.a .therapeutic .effect .is .the: .
A. .Minimum .adverse .effect .level .
B. .Peak .of .action .
C. .Onset .of .action .
D. .Therapeutic .range .- .CORRECT .ANSWER-C. .Onset .of .action
Phenytoin .requires .a .trough .level .be .drawn. .Peak .and .trough .levels .are .done: .A.
.When .the .drug .has .a .wide .therapeutic .range .
B. .When .the .drug .will .be .administered .for .a .short .time .only
C. .When .there .is .a .high .correlation .between .the .dose .and .saturation .of .receptor
.sites
D. .To .determine .if .a .drug .is .in .the .therapeutic .range .- .CORRECT .ANSWER-D. .To
.determine .if .a .drug .is .in .the .therapeutic .range
A .laboratory .result .indicates .the .peak .level .for .a .drug .is .above .the .minimum
.toxic .concentration. .This .means .that .the: .
A. .Concentration .will .produce .therapeutic .effects .
B. .Concentration .will .produce .an .adverse .response .
C. .Time .between .doses .must .be .shortened .
D. .Duration .of .action .of .the .drug .is .too .long .- .CORRECT .ANSWER-B.
.Concentration .will .produce .an .adverse .response
Drugs .that .are .receptor .agonists .may .demonstrate .what .property? .
A. .Irreversible .binding .to .the .drug .receptor .site .
B. .Up-regulation .with .chronic .use .
C. .Desensitization .or .down-regulation .with .continuous .use .
D. .Inverse .relationship .between .drug .concentration .and .drug .action .- .CORRECT
.ANSWER-C. .Desensitization .or .down-regulation .with .continuous .use
Drugs .that .are .receptor .antagonists, .such .as .beta .blockers, .may .cause: .
A. .Down-regulation .of .the .drug .receptor .
B. .An .exaggerated .response .if .abruptly .discontinued .
C. .Partial .blockade .of .the .effects .of .agonist .drugs .
D. .An .exaggerated .response .to .competitive .drug .agonists .- .CORRECT .ANSWER-
B. .An .exaggerated .response .if .abruptly .discontinued
Factors .that .affect .gastric .drug .absorption .include:
A. .Liver .enzyme .activity
B. .Protein-binding .properties .of .the .drug .molecule
C. .Lipid .solubility .of .the .drug .
D. .Ability .to .chew .and .swallow .- .CORRECT .ANSWER-C. .Lipid .solubility .of .the
.drug
Drugs .administered .via .intravenous .(IV) .route:
A. .Need .to .be .lipid .soluble .in .order .to .be .easily .absorbed
B. .Begin .distribution .into .the .body .immediately
C. .Are .easily .absorbed .if .they .are .nonionized
Answers A+ Graded (2025)
Nurse .practitioner .prescriptive .authority .is .regulated .by:
A. .The .National .Council .of .State .Boards .of .Nursing
B. .The .U.S. .Drug .Enforcement .Administration
C. .The .State .Board .of .Nursing .for .each .state
D. .The .State .Board .of .Pharmacy .- .CORRECT .ANSWER-C. .The .State .Board .of
.Nursing .for .each .state
Physician .Assistant .(PA) .prescriptive .authority .is .regulated .by:
A. .The .National .Council .of .State .Boards .of .Nursing
B. .The .U.S. .Drug .Enforcement .Administration
C. .The .State .Board .of .Nursing
D. .The .State .Board .of .Medical .Examiners .- .CORRECT .ANSWER-D. .The .State
.Board .of .Medical .Examiners
Clinical .judgment .in .prescribing .includes: .
A. .Factoring .in .the .cost .to .the .patient .of .the .medication .prescribed .
B. .Always .prescribing .the .newest .medication .available .for .the .disease .process
.C. .Handing .out .drug .samples .to .poor .patients .
D. .Prescribing .all .generic .medications .to .cut .costs .- .CORRECT .ANSWER-A.
.Factoring .in .the .cost .to .the .patient .of .the .medication .prescribed
Criteria .for .choosing .an .effective .drug .for .a .disorder .include:
A. .Asking .the .patient .what .drug .they .think .would .work .best .for .them .
B. .Consulting .nationally .recognized .guidelines .for .disease .management
C. .Prescribing .medications .that .are .available .as .samples .before .writing .a
.prescription .
D. .Following .U.S. .Drug .Enforcement .Administration .(DEA) .guidelines .for
.prescribing .- .CORRECT .ANSWER-B. .Consulting .nationally .recognized
.guidelines .for .disease .management
Nurse .practitioner .practice .may .thrive .under .health-care .reform .due .to:
A. .The .demonstrated .ability .of .nurse .practitioners .to .control .costs .and .improve
.patient .outcomes .
B. .The .fact .that .nurse .practitioners .will .be .able .to .practice .independently .
C. .The .fact .that .nurse .practitioners .will .have .full .reimbursement .under .health-
care .reform .
,D. .The .ability .to .shift .accountability .for .Medicaid .to .the .state .level .- .CORRECT
.ANSWER-A. .The .demonstrated .ability .of .nurse .practitioners .to .control .costs .and
.improve .patient .outcomes
A .patient's .nutritional .intake .and .lab .work .reflects .hypoalbuminemia. .This .is
.critical .to .prescribing .because: .
A. .Distribution .of .drugs .to .target .tissue .may .be .affected .
B. .The .solubility .of .the .drug .will .not .match .the .site .of .absorption .
C. .There .will .be .less .free .drug .available .to .generate .an .effect .
D. .Drugs .bound .to .albumin .are .readily .excreted .by .the .kidney .- .CORRECT
.ANSWER-A. .Distribution .of .drugs .to .target .tissue .may .be .affected
Drugs .that .have .a .significant .first-pass .effect: .A. .Must .be .given .by .the .enteral
.(oral) .route .only .
B. .Bypass .the .hepatic .circulation .
C. .Are .rapidly .metabolized .by .the .liver .and .may .have .little .if .any .desired .action .
D. .Are .converted .by .the .liver .to .more .active .and .fat-soluble .forms .- .CORRECT
.ANSWER-C. . Are .rapidly .metabolized .by .the .liver .and . may . have .little .if .any
.desired .action
The .route .of .excretion .of .a .volatile .drug .will .likely .be: .
A. .The .kidneys .
B. .The .lungs .
C. .The .bile .and .feces .
D. .The .skin .- .CORRECT .ANSWER-B. .The .lungs
Medroxyprogesterone .(Depo .Provera) .is .prescribed .IM .to .create .a .storage
.reservoir .of .the .drug. .Storage .reservoirs: .
A. .Assure .that .the .drug .will .reach .its .intended .target .tissue .
B. .Are .the .reason .for .giving .loading .doses .
C. .Increase .the .length .of .time .a .drug .is .available .and .active .
D. .Are .most .common .in .collagen .tissues .- .CORRECT .ANSWER-C. .Increase .the
.length .of .time .a .drug .is .available .and .active
The .NP .chooses .to .give .cephalexin .every .8 .hours .based .on .knowledge .of .the
.drug's: .
A. .Propensity .to .go .to .the .target .receptor .
B. .Biological .half-life .
C. .Pharmacodynamics .
D. .Safety .and .side .effects .- .CORRECT .ANSWER-B. .Biological .half-life
Azithromycin .dosing .requires .the .first .day's .dose .be .twice .those .of .the .other .4
.days .of .the .prescription. .This .is .considered .a .loading .dose. .A .loading .dose: .A.
.Rapidly .achieves .drug .levels .in .the .therapeutic .range .
B. .Requires .four .to .five .half-lives .to .attain .
C. .Is .influenced .by .renal .function .
D. .Is .directly .related .to .the .drug .circulating .to .the .target .tissues .- .CORRECT
.ANSWER-A. .Rapidly .achieves .drug .levels . in .the .therapeutic .range
, The .point .in .time .on .the .drug .concentration .curve .that .indicates .the .first .sign .of
.a .therapeutic .effect .is .the: .
A. .Minimum .adverse .effect .level .
B. .Peak .of .action .
C. .Onset .of .action .
D. .Therapeutic .range .- .CORRECT .ANSWER-C. .Onset .of .action
Phenytoin .requires .a .trough .level .be .drawn. .Peak .and .trough .levels .are .done: .A.
.When .the .drug .has .a .wide .therapeutic .range .
B. .When .the .drug .will .be .administered .for .a .short .time .only
C. .When .there .is .a .high .correlation .between .the .dose .and .saturation .of .receptor
.sites
D. .To .determine .if .a .drug .is .in .the .therapeutic .range .- .CORRECT .ANSWER-D. .To
.determine .if .a .drug .is .in .the .therapeutic .range
A .laboratory .result .indicates .the .peak .level .for .a .drug .is .above .the .minimum
.toxic .concentration. .This .means .that .the: .
A. .Concentration .will .produce .therapeutic .effects .
B. .Concentration .will .produce .an .adverse .response .
C. .Time .between .doses .must .be .shortened .
D. .Duration .of .action .of .the .drug .is .too .long .- .CORRECT .ANSWER-B.
.Concentration .will .produce .an .adverse .response
Drugs .that .are .receptor .agonists .may .demonstrate .what .property? .
A. .Irreversible .binding .to .the .drug .receptor .site .
B. .Up-regulation .with .chronic .use .
C. .Desensitization .or .down-regulation .with .continuous .use .
D. .Inverse .relationship .between .drug .concentration .and .drug .action .- .CORRECT
.ANSWER-C. .Desensitization .or .down-regulation .with .continuous .use
Drugs .that .are .receptor .antagonists, .such .as .beta .blockers, .may .cause: .
A. .Down-regulation .of .the .drug .receptor .
B. .An .exaggerated .response .if .abruptly .discontinued .
C. .Partial .blockade .of .the .effects .of .agonist .drugs .
D. .An .exaggerated .response .to .competitive .drug .agonists .- .CORRECT .ANSWER-
B. .An .exaggerated .response .if .abruptly .discontinued
Factors .that .affect .gastric .drug .absorption .include:
A. .Liver .enzyme .activity
B. .Protein-binding .properties .of .the .drug .molecule
C. .Lipid .solubility .of .the .drug .
D. .Ability .to .chew .and .swallow .- .CORRECT .ANSWER-C. .Lipid .solubility .of .the
.drug
Drugs .administered .via .intravenous .(IV) .route:
A. .Need .to .be .lipid .soluble .in .order .to .be .easily .absorbed
B. .Begin .distribution .into .the .body .immediately
C. .Are .easily .absorbed .if .they .are .nonionized
