Conceptual Actual Emended Exam Questions With
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1. What are the 6 most common preservatives? - ANSWER
chlorohexadine, thimerosal, EDTA, PAPB/Dymed, Polyquad, and benzyl
alcohol
2. What is cholorohexadine used for? - ANSWER used for GPs in high
concentration due to low binding capacity
3. What is the spectrum of activity for cholorohexadine? - ANSWER
bactericidal but less effective for serratia, yeast, or fungi
4. How is chlorohexadine's efficacy improved? - ANSWER by adding EDTA
or thimerosal
5. What is thimerosal? - ANSWER an organic mercurial compound that
used to be a common preservative (less common now due to sensitivity)
6. What is the spectrum of activity for thimerosal? - ANSWER bactericidal
with a broad spectrum but very slow acting, but ineffective for
pseudomonas in low concentrations
,7. What is EDTA? - ANSWER Ethylenediamine Tetra Acetate; a chelating
agent (not a true preservative)
8. What is the purpose of using EDTA? - ANSWER used in combination for
synergistic effects, especially against pseudomonas
9. How does EDTA work? - ANSWER disrupts bacterial cell wall to give
preservative better efficacy
10.What is PAPB/Dymed? - ANSWER Polyaminopropyl biguanide; a soft and
GP contact solution preservative (30 - 50x higher concentration for GPs)
11.What is the spectrum of activity for PAPB/Dymed? - ANSWER effective
against acanthamoeba and better against serratia than chlorohexadine
12.What solutions is PAPB/Dymed used in? - ANSWER Boston Advance
Conditioner, Boston Simplus, and all Baush and Laumb products
13.What solutions is chlorohexadine used in? - ANSWER Boston simplus,
Boston original conditioning
14.What solutions is Polyquad found in? - ANSWER uniquePh, Optifree,
and most Alcon artificial tears
, 15.Why is benzyl alcohol used in some solutions? - ANSWER good
disinfection capabilities and effective with lipid removal, negligible binding
to BP surface
16.What solutions use Benzyl alcohol? - ANSWER Optimum CDS and
Menicare CDS
17.What preservatives are used in Boston original? - ANSWER
Chlorohexadine
18.What preservatives are used in Boston Advance? - ANSWER
PAPB/Dymed
19.What preservatives are used in Boston Simplus? - ANSWER
Chlorhexadine plus PAPB/Dymed
20.What preservatives are used in Unique pH? - ANSWER Polyquad
What preservative is used in optimum extra strength cleaner by lobob? - ANSWER
trick! non-preserved
Describe hydrogen peroxide solutions - ANSWER non-preserved
FDA approved with GPs
rub required to prevent deposits
some prefer to apply lens with artificial tears instead of neutralized saline
, Describe Boston Conditioning solution - ANSWER -disinfects and cusions
-wetting agent coats surface of lenses to make them smooth, wet, and
comfortable
-helps reduce friction between lens and eye
What are 3 examples of enzymatic cleaners? Describe each - ANSWER 1)
Boston One-Step Liquid enzyme cleaner
-approved for weekly use/PRN basis
-add 1 drop to storage solution as an adjunct
-subtilisin proteolytic enzyme
2) optifree supra clens daily protein remover
-pancreatin derivative
-also removes lipids
(recalled, but still on amazon)
3)walgreens extra strength daily cleaner
-excellent restorer lens surface wetting
What is a periodic cleaner? - ANSWER -removes protein and disinfectants
-strong oxidizing agent
-menicon progent:
approved for use every 2 weeks