QUESTIONS AND CORRECT ANSWERS
Erasistratus - Correct answers✔Early philosopher that studied animal anatomy and was the first
to demonstrate that the heart's valves limit blood flow to one direction
Early 1500's - Correct answers✔The time period signifying the start of the modern experimental
era
William Harvey - Correct answers✔English physician and scientist who described the circulation
of the blood in the 1600s
Carl Linnaeus - Correct answers✔Physician and zoologist who developed a taxonomic system
that classified organisms based on anatomical traits
Claude Bernard - Correct answers✔Validated the scientific method in France (1800s)
Louis Pasteur - Correct answers✔A French chemist, this man discovered that heat could kill
bacteria that otherwise spoiled liquids. Studied infectious disease.
Robert Koch - Correct answers✔Developed the culture plate method to identify pathogens
Dr. Walter Reed - Correct answers✔Confirmed that yellow fever was transmitted via mosquito
species in the early 1900s
Compound microscope - Correct answers✔Invented in the late 1500s, aided in research
development
,Research study - Correct answers✔Systematic investigation to establish facts; Define question --
> formulate objective framework --> establish hypothesis --> create research design --> identify
variables --> collect/analyze data --> report data and conclusions
Grants - Correct answers✔Provide money for 3 to 5-year period during which the investigator
must conduct the study and publish results in one or more scientific journals
NIH - Correct answers✔Most ______ grants go to research programs at colleges and universities
NIH & NSF - Correct answers✔what are the 2 main public agencies that fund research
NSF - Correct answers✔Agency supporting non-biomedical research that may involved animals
(physics, chemistry, engineering, etc.)
Office of Research and Grants - Correct answers✔Administrative unit that manages grants,
supports, research activities, assists grantees in managing their grants, helps search for grant
opportunities, and protects intellectual property rights
OLAW (Office of Laboratory Animal Welfare) - Correct answers✔monitors compliance with
PHS policy by assured institutions through site visits
IACUC - Correct answers✔Mandated by federal law and institutional policies that govern the
use of animals in research
CEO - Correct answers✔Appoints members of the IACUC
,USDA, OLAW, and AAALAC - Correct answers✔The IACUC can suspend animal-related
activities at any time, but they must notify _________
5 consecutive hours - Correct answers✔the twenty-eight hour law dictates that animals cannot be
transported for >28 hours without being unloaded for at least _______ for rest, water, and food
Cruelty to Animals Act (Britain 1876) - Correct answers✔first law limiting animal
experimentation
AWR (Animal Welfare Regulations) - Correct answers✔mandate that protocols for USDA-
covered species may only be approved for 1 year
Laboratory Animal Welfare Act of 1966 - Correct answers✔first law in U.S. addressing animal
use in research; established care and use standards for animals including housing, sale, transport,
dealer licensing, facility registration, and identification of dogs and cats
USDA - Correct answers✔tasked with enforcing the laboratory animal welfare act of 1966
Animal Welfare Act (AWA) - Correct answers✔the laboratory animal welfare act of 1966 was
renamed to this in 1970 to cover all warm-blooded animals used in research, sold as pets, or used
in exhibitions; required all animal dealers to be licensed and mandated use of pain-relieving
drugs for animals used in regulated activities
1985 amendment to the animal welfare act (AWA) - Correct answers✔called for excersize for
dogs and psychological enrichment for primates, minimizing pain/distress and only 1 major
surgery/animal with exceptions
National Agricultural Library (NAL) - Correct answers✔assists researchers in preventing
unnecessary duplication, reducing pain and distress (resulted from 1985 amendment to AWA)
, live or dead dog, cat, primate guinea pig, hamster, rabbit, or other warm-blooded animals used
for research/pets; excludes birds, rats, mice, farm animals, and horses (not used for research) -
Correct answers✔AWA definition for 'animal'
Animal Welfare Regulations - Correct answers✔developed by the USDA to enforce the AWA;
establishes rules and standards for humane care and treatment of covered species
Terms, Regulations, Standards, Rules of Practice - Correct answers✔Four parts of the animal
welfare regulations (AWR) developed by the USDA to enforce the AWA
Animal and Plant Health Inspection Service (APHIS) - Correct answers✔administers AWR
(animal welfare regulations) to enforce the AWA (animal welfare act)
USDA veterinary medical officers (VMO) - Correct answers✔conduct unannounced inspections
of animal care and use programs following the Animal Care Inspection Guide in order to enforce
the AWA through APHIS
APHIS - Correct answers✔Animal and Plant Health Inspection Service
IO - Correct answers✔person responsible for making sure the organization is AWA-compliant
USDA - Correct answers✔research facilities must register with ______ if they use AWA-covered
species, registration must be signed by IO/CEO
Annually - Correct answers✔Institutions housing USDA-covered animals must submit a report
to the USDA including location of animal facilities, how many animals used, and pain categories
HOW OFTEN?