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1. What criteria are used to diagnose alcohol use disorder (AUD) in the DSM-
5-TR? - ANSWER ✔ The DSM-5-TR uses 11 criteria, including impaired
control, social impairment, risky use, and pharmacologic indicators
(tolerance/withdrawal). A diagnosis is made based on:
Mild: 2-3 symptoms
Moderate: 4-5 symptoms
Severe: 6 or more symptoms
2. What are common behavioral signs of alcohol use disorder? - ANSWER ✔
Cravings for alcohol
Continued use despite consequences
Drinking larger amounts or for longer than intended
Failed attempts to cut down
Neglect of responsibilities
3. What are the symptoms of alcohol intoxication? - ANSWER ✔ Slurred
speech
Incoordination
Unsteady gait
Nystagmus
Impaired attention or memory
Stupor or coma (in severe cases)
4. What are the symptoms of alcohol withdrawal? - ANSWER ✔ Tremors (6-
12 hours after last drink)
Anxiety, agitation
, Tachycardia, hypertension
Insomnia
Seizures (12-48 hours after last drink)
Delirium tremens (DTs) - Hallucinations, confusion, autonomic instability
(48-72 hours after last drink)
5. Buprenorphine has poor bioavailability and is usually administered -
ANSWER ✔ sublingually as a tablet or as a film.
6. In the United States, methadone can be dispensed only at - ANSWER ✔
outpatient opioid treatment program (OTP) certified by SAMHSA and
registered with the DEA or to a hospitalized patient in an emergency.
SAMHSA-certified OTP facilities provide daily doses of methadone under
direct supervision until the patient is stable enough to receive take-home
7. Buprenorphine can also assist detoxification in the outpatient setting
The first day's dosing should occur under medical supervision to -
ANSWER ✔ minimize the risk of buprenorphine-precipitated withdrawal.
8. For buprenorphine The physician usually instructs patients to arrive in
withdrawal, which typically starts - ANSWER ✔ 12 hours after the last dose
of a short-acting opioid or 24 hours after a long-acting opioid like
methadone.
9. The first dose of buprenorphine is usually - ANSWER ✔ 2 mg, and if there
are no signs of precipitated withdrawal, subsequent 2-mg doses are given at
the clinic every 2 hours, with additional doses given to take at home, until
the elimination of withdrawal.
the total daily dose needed on the first day is 8 to 12 mg.
10.The initial dose of methadone is usually - ANSWER ✔ 20 to 30 mg orally
11.For methadone Generally, a period of dose stabilization, at a minimum of -
ANSWER ✔ 4 weeks in duration, is necessary before a slow dose reduction
schedule. In the outpatient setting, gradual dose reductions (e.g., 3 percent
per week), have a higher likelihood of success, with even slower reductions
once the total daily dose is down to 20 to 30 mg/day
,12.Opioid antagonists - ANSWER ✔ Naloxone
Nalmefene
Naltrexone
13.Naloxone mechanism of action - ANSWER ✔ bind to the
receptor but do not exert any activity. These medications function as
antagonists
Naloxone reverses an overdose; as it is a short-acting agent
14.Naltrexone - ANSWER ✔ a long-acting agent used following detoxification
as a strategy to prevent recurrent physiologic dependence and relapse
15.Buprenorphine - ANSWER ✔ an opioid partial agonist that binds to the
receptor but activates
it only partially. Buprenorphine is used to assist detoxification and as a
maintenance agent.
16.Substantial reductions in illicit drug use, antisocial behaviors, and
psychiatric
distress among patients dependent on cocaine or heroin are much more
likely
following treatment - ANSWER ✔ Three months
17.National Institute on Drug Abuse suggested the following categories of
treatment: - ANSWER ✔ long-term residential treatment, short-term
residential treatment,
outpatient treatment programs, individualized drug counseling, group
counseling, and treatments for individuals involved in the criminal justice
System
18.Detoxification and Withdrawal Management
Mild Withdrawal: - ANSWER ✔ supportive care and monitoring
19.Moderate to Severe Withdrawal: - ANSWER ✔ 1. Benzodiazepines (e.g.,
Diazepam, Lorazepam, Chlordiazepoxide) - Prevent seizures
and manage withdrawal symptoms.
2. Adjunctive Medications: Clonidine, gabapentin, or antipsychotics (PRN
for agitation).
, 20.A 10-year-old with autism and aggression is prescribed risperidone. What
side effect should be monitored? - ANSWER ✔ Weight gain, sedation,
metabolic effects, increased prolactin.
21.What role does occupational therapy (OT) play in autism treatment? -
ANSWER ✔ Helps with fine motor skills, self-care, and sensory processing
difficulties.
22.What are two non-medication strategies to help with aggression in ASD? -
ANSWER ✔ Behavioral therapy, structured routines, sensory integration
therapy.
23.A 6-year-old nonverbal autistic child struggles to communicate. What
alternative communication method can help? - ANSWER ✔ Picture
Exchange Communication System (PECS).
24.What therapy is the gold standard for ASD treatment? - ANSWER ✔
Applied Behavior Analysis (ABA).
25.How does toxic stress from ACEs impact brain development? - ANSWER ✔
Dysregulates the HPA axis, leading to chronic cortisol elevation, affecting
memory, emotional regulation, and impulse control.
26.What are the 10 categories of ACEs? - ANSWER ✔ Abuse (physical,
emotional, sexual), Neglect (physical, emotional), Household dysfunction
(mental illness, incarcerated relative, substance abuse, mother treated
violently, divorce).
27.What is the Adverse Childhood Experiences (ACE) study? - ANSWER ✔ A
landmark study linking childhood trauma to long-term physical & mental
health risks.
28.What is the black box warning for stimulants used for ADHD? - ANSWER
✔ Risk of abuse, dependency, and potential cardiovascular events.