WGU D027 Performance Assessment-
Advanced Pathopharmacological
Foundations Exam 2025 With 100%
Correct Answers
Which of the following is not a cellular function? CORRECT
ANSWER Combustion
What are mitochondria responsible for? CORRECT ANSWER
Energy production
Which if the following can cause edema? CORRECT ANSWER
Increased lymphatic pressure
Which of the following best describes the result of cellular
reproduction? CORRECT ANSWER Two diploid cells, called
daughter cells, are produced.
What is an example of both hyperplasia and hypertrophy?
CORRECT ANSWER Uterine enlargement due to pregnancy
,What regulates the sodium balance? CORRECT ANSWER
aldosterone
What is the alteration if the extracellular fluid volume is less
than normal? CORRECT ANSWER Hypotonic
When in excess, what do buffers absorb? CORRECT ANSWER
Hydrogen
What is the process by which RNA directs the synthesis of
polypeptides? CORRECT ANSWER Translation
What is the recurrence rate (%) for autosomal dominant disease?
CORRECT ANSWER 50%
What is the proportion of the population affected by a disease at
the specific point in time? CORRECT ANSWER Prevalence
rate
Which of the following should be completed when a disease is
multifactorial but has a larger genetic component? CORRECT
ANSWER Get a thorough family history
,A 44-year-old woman has recently been diagnosed with
advanced metastatic non-small-cell lung cancer. Genetic testing
is ordered to determine if the patient's tumor has any genomic
alterations and to guide treatment decisions. A few weeks later,
the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this
information, what types of genetic mutation does this patient
have? Choose 2 answers CORRECT ANSWER 1. ALK
mutation
2. EGFR mutation
A 20-year-old male meets with an APN to discuss symptoms
that have been slowly progressing over the past several years.
He is mainly concerned because he has been falling frequently.
Lately, he has noticed it takes longer/more difficult to change
positions from sitting to standing than it used to in the past. He
has been waking up with muscle/joint stiffness. No family
history of any chronic or genetic diseases. Which condition is
likely to be the cause of these symptoms? CORRECT ANSWER
Becker muscular dystrophy
A patient with systemic lupus erythematosus (SLE) is diagnosed
with idiopathic thrombocytopenic purpura (ITP). Which
statement should the provider give the patient regarding the
pathophysiology of SLE and its relation to thrombocytopenia?
CORRECT ANSWER SLE disrupts immune homeostasis and
promotes development of self-reactive antibodies.
, A 75-year-old female presents to the emergency department
with an irregular heart rate of 130. What can be ascertained
about this patient's findings given the limited information?
CORRECT ANSWER She is diagnosed with atrial fibrillation
and needs her heart rate controlled with metoprolol (Lopressor).
A 45-year-old female fears that she is having a stroke and takes
herself to an emergency room. After several diagnostic and
laboratory tests, the patient is diagnosed with Cushing disease.
Which lab abnormality would be present in this patient?
CORRECT ANSWER Increased cortisol
A two-year-old child presents with a clear runny nose and cough
which has lasted 3 days. The child's mother reports the cough
sounds like a barking noise. The child is sleeping in the mother's
arms and appears to have stridor. The child's mother also reports
an axillary temperature of 101°F last night. Which management
technique is appropriate for this child's symptoms? CORRECT
ANSWER Oral steroids and breathing treatments
A patient who is elderly presents with recent memory loss,
urinary incontinence, and hallucinations. The patient's family
also states she is having daytime sleepiness and impaired
judgment. Which lab and diagnostic tests should be ordered as
Advanced Pathopharmacological
Foundations Exam 2025 With 100%
Correct Answers
Which of the following is not a cellular function? CORRECT
ANSWER Combustion
What are mitochondria responsible for? CORRECT ANSWER
Energy production
Which if the following can cause edema? CORRECT ANSWER
Increased lymphatic pressure
Which of the following best describes the result of cellular
reproduction? CORRECT ANSWER Two diploid cells, called
daughter cells, are produced.
What is an example of both hyperplasia and hypertrophy?
CORRECT ANSWER Uterine enlargement due to pregnancy
,What regulates the sodium balance? CORRECT ANSWER
aldosterone
What is the alteration if the extracellular fluid volume is less
than normal? CORRECT ANSWER Hypotonic
When in excess, what do buffers absorb? CORRECT ANSWER
Hydrogen
What is the process by which RNA directs the synthesis of
polypeptides? CORRECT ANSWER Translation
What is the recurrence rate (%) for autosomal dominant disease?
CORRECT ANSWER 50%
What is the proportion of the population affected by a disease at
the specific point in time? CORRECT ANSWER Prevalence
rate
Which of the following should be completed when a disease is
multifactorial but has a larger genetic component? CORRECT
ANSWER Get a thorough family history
,A 44-year-old woman has recently been diagnosed with
advanced metastatic non-small-cell lung cancer. Genetic testing
is ordered to determine if the patient's tumor has any genomic
alterations and to guide treatment decisions. A few weeks later,
the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this
information, what types of genetic mutation does this patient
have? Choose 2 answers CORRECT ANSWER 1. ALK
mutation
2. EGFR mutation
A 20-year-old male meets with an APN to discuss symptoms
that have been slowly progressing over the past several years.
He is mainly concerned because he has been falling frequently.
Lately, he has noticed it takes longer/more difficult to change
positions from sitting to standing than it used to in the past. He
has been waking up with muscle/joint stiffness. No family
history of any chronic or genetic diseases. Which condition is
likely to be the cause of these symptoms? CORRECT ANSWER
Becker muscular dystrophy
A patient with systemic lupus erythematosus (SLE) is diagnosed
with idiopathic thrombocytopenic purpura (ITP). Which
statement should the provider give the patient regarding the
pathophysiology of SLE and its relation to thrombocytopenia?
CORRECT ANSWER SLE disrupts immune homeostasis and
promotes development of self-reactive antibodies.
, A 75-year-old female presents to the emergency department
with an irregular heart rate of 130. What can be ascertained
about this patient's findings given the limited information?
CORRECT ANSWER She is diagnosed with atrial fibrillation
and needs her heart rate controlled with metoprolol (Lopressor).
A 45-year-old female fears that she is having a stroke and takes
herself to an emergency room. After several diagnostic and
laboratory tests, the patient is diagnosed with Cushing disease.
Which lab abnormality would be present in this patient?
CORRECT ANSWER Increased cortisol
A two-year-old child presents with a clear runny nose and cough
which has lasted 3 days. The child's mother reports the cough
sounds like a barking noise. The child is sleeping in the mother's
arms and appears to have stridor. The child's mother also reports
an axillary temperature of 101°F last night. Which management
technique is appropriate for this child's symptoms? CORRECT
ANSWER Oral steroids and breathing treatments
A patient who is elderly presents with recent memory loss,
urinary incontinence, and hallucinations. The patient's family
also states she is having daytime sleepiness and impaired
judgment. Which lab and diagnostic tests should be ordered as
