Advanced Pharmacology Final Exam Review With Complete Solutions.

Advanced Pharmacology Final Exam
Review With Complete Solutions.




Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? - CORRECT
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ANSWER✔✔To inhibit the development of tolerance
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What does a low level of thyroid-stimulating hormone indicate? - CORRECT ANSWER✔✔Hyperthroidism
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What would be the best option to treat a newly diagnosed patient with a low TSH level with? - CORRECT
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ANSWER✔✔Propanolol (Inderal)
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Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - CORRECT ANSWER✔✔Aldosterone
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antagonist
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Heparin exerts its therapeutic action by what? - CORRECT ANSWER✔✔Upregulating the activity of one of
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the body's natural anticoagulant molecules, antithrombin III
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What physiologic action happens when the offending drug is administered during an anaphylactic reaction.
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- CORRECT ANSWER✔✔Mast cells liberate large doses of histamine.
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, What are two systemic psoriasis medications? - CORRECT ANSWER✔✔Photo-therapy and topical
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corticosteroids
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What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
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hypertension? - CORRECT ANSWER✔✔Thiazide diuretics
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What is the effect of cardiac glycosides? - CORRECT ANSWER✔✔Digitalis glycosides have a negative
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chronotropic effect on the cardiac muscle cells.
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Amenorrhea is the most common side effect of which birth control medication? - CORRECT ANSWER✔✔
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Medroxyprogesterone (Depo-Provera) j




What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites? -
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CORRECT ANSWER✔✔Atenolol (Tenormin)
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What type of action does nitrates have on the body? - CORRECT ANSWER✔✔Reduction in systemic venous
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tone.
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What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known
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coronary artery disease? - CORRECT ANSWER✔✔100mg/dl or less.
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What is the MOA of group IV anti-dysrhythmia drugs? - CORRECT ANSWER✔✔Depressing phase 4
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depolarization and lengthening phases 1 and 2 repolarization.
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Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish
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eumetabolic state in a patient with Graves' disease? - CORRECT ANSWER✔✔Anti-thyroid drugs.
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