Nurse 257 Final Exam
Filgrastim action - answer-stimulates WBCs (specifically neutrophils)
Filgrastim pharmacokinetics - answerIV or SubQ
Filgrastim contraindications/cautions - answer-allergies to E.coli
Filgrastim nursing considerations - answer-obtain baseline CBC, monitor every 3rd day
until neutrophils (ANC) >1000 for 3 consecutive CBCs
-glomerular nephritis may occur, notify MD may need to decrease dose or D/C
-monitor for upper abdominal/shoulder pain for enlarged spleen/rupture
-monitor for capillary leak syndrome (hypotension, hypoalbuminemia, edema, and
hemoconcentration)
-watch for ARDS
-watch for cutaneous vasculitis (purpura, erythema) notify MD
Filgrastim patient teaching - answer-latex allergy=no prefilled syringes
-report purpura or erythema; left upper abdominal or shoulder pain
-seek immediate care if swelling, decreased urination, SOB, abdominal
swelling/fullness, dizziness, or fatigue occurs
-repeat blood tests
Filgrastim common S/E - answer-thrombocytopenia
Epoetin Alpha action - answer-stimulates RBCs
-tx. of anemia
Epoetin Alpha pharmacokinetics - answerIV and subQ
Epoetin Alpha contraindications/cautions - answer-hypersensitivity to albumin
-uncontrolled HTN
Epoetin Alpha nursing considerations - answer-renal disease=severe CV events when
Hb > 11 = additional doses of heparin
-evaluate iron status
-monitor BP
-monitor Hb weekly
-if therapy >12 weeks & ineffective, it probably wont work
-DVT prophylaxis
Epoetin Alpha patient teaching - answer-pain/discomfort in limbs and pelvis, feeling
cold, and sweating may occur after injection
Filgrastim action - answer-stimulates WBCs (specifically neutrophils)
Filgrastim pharmacokinetics - answerIV or SubQ
Filgrastim contraindications/cautions - answer-allergies to E.coli
Filgrastim nursing considerations - answer-obtain baseline CBC, monitor every 3rd day
until neutrophils (ANC) >1000 for 3 consecutive CBCs
-glomerular nephritis may occur, notify MD may need to decrease dose or D/C
-monitor for upper abdominal/shoulder pain for enlarged spleen/rupture
-monitor for capillary leak syndrome (hypotension, hypoalbuminemia, edema, and
hemoconcentration)
-watch for ARDS
-watch for cutaneous vasculitis (purpura, erythema) notify MD
Filgrastim patient teaching - answer-latex allergy=no prefilled syringes
-report purpura or erythema; left upper abdominal or shoulder pain
-seek immediate care if swelling, decreased urination, SOB, abdominal
swelling/fullness, dizziness, or fatigue occurs
-repeat blood tests
Filgrastim common S/E - answer-thrombocytopenia
Epoetin Alpha action - answer-stimulates RBCs
-tx. of anemia
Epoetin Alpha pharmacokinetics - answerIV and subQ
Epoetin Alpha contraindications/cautions - answer-hypersensitivity to albumin
-uncontrolled HTN
Epoetin Alpha nursing considerations - answer-renal disease=severe CV events when
Hb > 11 = additional doses of heparin
-evaluate iron status
-monitor BP
-monitor Hb weekly
-if therapy >12 weeks & ineffective, it probably wont work
-DVT prophylaxis
Epoetin Alpha patient teaching - answer-pain/discomfort in limbs and pelvis, feeling
cold, and sweating may occur after injection
