8/17/25, 8:31
AM
EXAM 3 NRS 340 EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE GRADED A++
2025/2026
Terms in this set (216)
G1: relatively dormant with some
RNA and protein synthesis S: DNA
cell cycle is synthesized, RNA and protein
synthesis continue G 2: RNA
synthesis
M: mitosis (cell division)
G0: resting phase, cells are not in the process of cell
division
what is the goal of chemo reduce the number of cancer cells present in
is to what? the primary tumor sites and metastatic tumor
sites
1. mitotic rate of the tissue from which the
tumor arises (more rapid/mitotic better
what factors determine response)
the response of cancer 2. size of the tumor, smaller the better
cells to chemo? 3. age of the tumor (younger the better)
4. location of the tumor
5. presence of resistant tumor cells just like bacteria with
1/28
,8/17/25, 8:31
AM
antibiotics
-when cancer begins to grow it is rapidly
what happens if tumor is dividing. as the tumor increases in size more
in the G0? cells become inactive and convert to a resting
state (G0), because chemo is more effective
against diving cells, cells can escape death
by staying in the G0.
asparaginase, prednisone
cancer agents specific to
G2 phase Antibiotics: bleomycin and etoposide
cancer agents specific to (antimetabolities)
S phase cytarabine, 5 fluorourcil, methotrexate
cancer agents specific to (vinka alkaloids)
mitosis vincristine, vinblastine, taxol
2/28
, 8/17/25, 8:31
AM
-able to increase the proportion of cells killed at one
time
why give chemo drugs in -reduces the possibility of drug resistance by
combo using drugs that have different mechanism of
action
-uses principals of synergy to maximize the effects of
other drugs
-drugs that have different toxic side effects
oral and IV are most common
what is the most common -major concern with IV administration of
route of chemo given? antineoplastic drug is possible irritation of the
vessel wall by the drug or even worse,
extravasation which causes local tissue
damage
what can cause dislodgement of needle from port, IV catheter
extravasation? damage or breakage, displacement or
migration of catheter from the vein
signs and symptoms of pain or burning, redness at IV site, induration
extravasation (swelling) usually occurs immediately, inability
to obtain blood return
1. stop administration of vesicant and IV fluids **
2. do not remove IV catheter ***
management of 3. open extravasation kit. attempt to aspirate residual
extravasation drug from catheter
4. notify physician
5. administer antidote, if known
examples vesicant cisplatin, adriamycin, daunorubicin, mitomycin,
agent includes these
3/28
AM
EXAM 3 NRS 340 EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE GRADED A++
2025/2026
Terms in this set (216)
G1: relatively dormant with some
RNA and protein synthesis S: DNA
cell cycle is synthesized, RNA and protein
synthesis continue G 2: RNA
synthesis
M: mitosis (cell division)
G0: resting phase, cells are not in the process of cell
division
what is the goal of chemo reduce the number of cancer cells present in
is to what? the primary tumor sites and metastatic tumor
sites
1. mitotic rate of the tissue from which the
tumor arises (more rapid/mitotic better
what factors determine response)
the response of cancer 2. size of the tumor, smaller the better
cells to chemo? 3. age of the tumor (younger the better)
4. location of the tumor
5. presence of resistant tumor cells just like bacteria with
1/28
,8/17/25, 8:31
AM
antibiotics
-when cancer begins to grow it is rapidly
what happens if tumor is dividing. as the tumor increases in size more
in the G0? cells become inactive and convert to a resting
state (G0), because chemo is more effective
against diving cells, cells can escape death
by staying in the G0.
asparaginase, prednisone
cancer agents specific to
G2 phase Antibiotics: bleomycin and etoposide
cancer agents specific to (antimetabolities)
S phase cytarabine, 5 fluorourcil, methotrexate
cancer agents specific to (vinka alkaloids)
mitosis vincristine, vinblastine, taxol
2/28
, 8/17/25, 8:31
AM
-able to increase the proportion of cells killed at one
time
why give chemo drugs in -reduces the possibility of drug resistance by
combo using drugs that have different mechanism of
action
-uses principals of synergy to maximize the effects of
other drugs
-drugs that have different toxic side effects
oral and IV are most common
what is the most common -major concern with IV administration of
route of chemo given? antineoplastic drug is possible irritation of the
vessel wall by the drug or even worse,
extravasation which causes local tissue
damage
what can cause dislodgement of needle from port, IV catheter
extravasation? damage or breakage, displacement or
migration of catheter from the vein
signs and symptoms of pain or burning, redness at IV site, induration
extravasation (swelling) usually occurs immediately, inability
to obtain blood return
1. stop administration of vesicant and IV fluids **
2. do not remove IV catheter ***
management of 3. open extravasation kit. attempt to aspirate residual
extravasation drug from catheter
4. notify physician
5. administer antidote, if known
examples vesicant cisplatin, adriamycin, daunorubicin, mitomycin,
agent includes these
3/28
