NR 547 FINAL EXAM
NR 547 FINAL EXAM NEWEST 2025/2026 COMPLETE 200 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW VERSION!!
A client previously responded well to sertraline but discontinued it after
remission. What is the most appropriate action?
A. Start a new medication class
B. Restart sertraline
C. Refer to a psychiatrist
D. Begin combination therapy
Restart sertraline-> If a client had a successful response in the past and no
contraindications have emerged, re-prescribing the same medication is typically
best practice.
Which client would benefit from a sedating antidepressant taken at bedtime?
A. A client with fatigue and hypersomnia
B. A client with chronic pain
C. A client with insomnia
D. A client with panic attacks
A client with insomnia-> Sedating antidepressants can serve dual purposes—
treating mood and improving sleep quality when dosed at night.
Which antidepressant class should be avoided unless the client has not
responded to other treatments, due to dietary restrictions and drug
interactions?
A. SSRIs
B. SNRIs
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, NR 547 FINAL EXAM
C. MAOIs
D. NDRIs
MAOIs-> MAOIs require strict dietary restrictions (e.g., tyramine-containing foods)
and have significant interaction risks, so they’re used only when other options fail.
Which of the following is true about prescribing for clients with comorbid
anxiety?
A. Choose an activating medication
B. Avoid medications that target norepinephrine
C. Fluoxetine is preferred for anxiety
D. SNRIs are always better tolerated
Avoid medications that target norepinephrine-> Norepinephrine can worsen
anxiety symptoms in sensitive individuals, so medications that elevate NE should
be used with caution in anxious clients.
Which SSRI is known to potentially activate clients and may cause panic in
clients with comorbid anxiety?
A. Paroxetine
B. Sertraline
C. Fluoxetine
D. Escitalopram
Fluoxetine-> Fluoxetine is activating and may lead to increased agitation or panic
in individuals with high baseline anxiety.
Which factor would most influence the decision to choose an antidepressant
with a longer half-life?
A. Severe depression
B. History of psychosis
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, NR 547 FINAL EXAM
C. Medication non-adherence
D. Advanced age
Medication non-adherence-> Long half-life medications like fluoxetine help
prevent withdrawal symptoms and maintain blood levels when doses are
occasionally missed.
Why must CYP450 interactions be considered when prescribing antidepressants?
A. They decrease medication cost
B. They affect liver enzyme production
C. They impact medication metabolism
D. They reduce sedation
They impact medication metabolism-> The CYP450 system is involved in breaking
down many medications. Interactions here can lead to toxicity or reduced
effectiveness.
What is a key factor in determining whether a prescribed antidepressant will
truly help the client?
A. Brand name status
B. Number of side effects
C. Client affordability and access
D. Speed of onset
Client affordability and access-> Even the most effective antidepressant won’t
work if the client can’t afford it or access it consistently.
What is the first step when an antidepressant is not providing adequate
symptom relief?
A. Stop the medication immediately
B. Add a second medication
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, NR 547 FINAL EXAM
C. Increase the dose gradually
D. Switch to a different medication class
Increase the dose gradually-> Before switching or augmenting, it’s important to
maximize the dose within the therapeutic range—many clients simply need a
higher dose for effectiveness.
If increasing the dose of an antidepressant does not lead to improvement, what
is a logical next step?
A. Switch to a different drug within the same class
B. Immediately prescribe an antipsychotic
C. Increase the dose again
D. Try a mood stabilizer
Switch to a different drug within the same class-> Sometimes one SSRI might not
be effective for a client, but another SSRI could be. This is a reasonable next step
before switching classes.
When would it be appropriate to switch to a drug in a different class of
antidepressants?
A. After one day of treatment
B. If the client had previous success with an MAOI
C. After two failed trials from the same class
D. When side effects are mild
After two failed trials from the same class-> If two medications in the same class
don’t work or aren’t tolerated, it’s usually time to try a different class (e.g., SSRI →
SNRI or NDRI).
What is a valid next step when partial improvement is seen but not full
remission with the current antidepressant?
A. Add a second medication to augment the response
4|Page
NR 547 FINAL EXAM NEWEST 2025/2026 COMPLETE 200 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW VERSION!!
A client previously responded well to sertraline but discontinued it after
remission. What is the most appropriate action?
A. Start a new medication class
B. Restart sertraline
C. Refer to a psychiatrist
D. Begin combination therapy
Restart sertraline-> If a client had a successful response in the past and no
contraindications have emerged, re-prescribing the same medication is typically
best practice.
Which client would benefit from a sedating antidepressant taken at bedtime?
A. A client with fatigue and hypersomnia
B. A client with chronic pain
C. A client with insomnia
D. A client with panic attacks
A client with insomnia-> Sedating antidepressants can serve dual purposes—
treating mood and improving sleep quality when dosed at night.
Which antidepressant class should be avoided unless the client has not
responded to other treatments, due to dietary restrictions and drug
interactions?
A. SSRIs
B. SNRIs
1|Page
, NR 547 FINAL EXAM
C. MAOIs
D. NDRIs
MAOIs-> MAOIs require strict dietary restrictions (e.g., tyramine-containing foods)
and have significant interaction risks, so they’re used only when other options fail.
Which of the following is true about prescribing for clients with comorbid
anxiety?
A. Choose an activating medication
B. Avoid medications that target norepinephrine
C. Fluoxetine is preferred for anxiety
D. SNRIs are always better tolerated
Avoid medications that target norepinephrine-> Norepinephrine can worsen
anxiety symptoms in sensitive individuals, so medications that elevate NE should
be used with caution in anxious clients.
Which SSRI is known to potentially activate clients and may cause panic in
clients with comorbid anxiety?
A. Paroxetine
B. Sertraline
C. Fluoxetine
D. Escitalopram
Fluoxetine-> Fluoxetine is activating and may lead to increased agitation or panic
in individuals with high baseline anxiety.
Which factor would most influence the decision to choose an antidepressant
with a longer half-life?
A. Severe depression
B. History of psychosis
2|Page
, NR 547 FINAL EXAM
C. Medication non-adherence
D. Advanced age
Medication non-adherence-> Long half-life medications like fluoxetine help
prevent withdrawal symptoms and maintain blood levels when doses are
occasionally missed.
Why must CYP450 interactions be considered when prescribing antidepressants?
A. They decrease medication cost
B. They affect liver enzyme production
C. They impact medication metabolism
D. They reduce sedation
They impact medication metabolism-> The CYP450 system is involved in breaking
down many medications. Interactions here can lead to toxicity or reduced
effectiveness.
What is a key factor in determining whether a prescribed antidepressant will
truly help the client?
A. Brand name status
B. Number of side effects
C. Client affordability and access
D. Speed of onset
Client affordability and access-> Even the most effective antidepressant won’t
work if the client can’t afford it or access it consistently.
What is the first step when an antidepressant is not providing adequate
symptom relief?
A. Stop the medication immediately
B. Add a second medication
3|Page
, NR 547 FINAL EXAM
C. Increase the dose gradually
D. Switch to a different medication class
Increase the dose gradually-> Before switching or augmenting, it’s important to
maximize the dose within the therapeutic range—many clients simply need a
higher dose for effectiveness.
If increasing the dose of an antidepressant does not lead to improvement, what
is a logical next step?
A. Switch to a different drug within the same class
B. Immediately prescribe an antipsychotic
C. Increase the dose again
D. Try a mood stabilizer
Switch to a different drug within the same class-> Sometimes one SSRI might not
be effective for a client, but another SSRI could be. This is a reasonable next step
before switching classes.
When would it be appropriate to switch to a drug in a different class of
antidepressants?
A. After one day of treatment
B. If the client had previous success with an MAOI
C. After two failed trials from the same class
D. When side effects are mild
After two failed trials from the same class-> If two medications in the same class
don’t work or aren’t tolerated, it’s usually time to try a different class (e.g., SSRI →
SNRI or NDRI).
What is a valid next step when partial improvement is seen but not full
remission with the current antidepressant?
A. Add a second medication to augment the response
4|Page
