8/17/25, 10:19
AM
NURS 306 PHARMACOLOGY ALE 5 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED LATEST UPDATE GRADED A+
+ 2025/2026
Terms in this set (137)
True or False False
Cimetidine works by Rationale: Cimetidine is an H2 receptor
blocking H1 blocker that reduces gastric acid secretion. It
does not affect H1 receptors, which are
receptors to reduce
targeted by antihistamines for allergic
allergic reactions.
conditions.
True or False False
Cimetidine should be Rationale: Cimetidine is best taken at bedtime,
taken in the as gastric acid secretion is highest at night. This
morning for maximum helps with ulcer healing and GERD symptom
effectiveness. relief.
True or False True
Cimetidine can cause Rationale: Long-term use of Cimetidine can
gynecomastia and interfere with androgen receptors, leading to
impotence when used side effects like gynecomastia (breast tissue
long-term. enlargement in men) and impotence.
Which of the following is b) Management of GERD and ulcers
a primary therapeutic Rationale: Cimetidine is an H2 blocker that
use of Cimetidine?
1/35
,8/17/25, 10:19
AM
a) Treatment of allergic decreases gastric acid secretion, making it
reactions useful for treating GERD, gastric ulcers, and
b) Management of GERD duodenal ulcers.
and ulcers
c) Reduction of blood
pressure
d) Relief of migraine
headaches
A patient taking d) All of the above
Cimetidine should avoid Rationale: Alcohol and smoking can worsen
which of the following? GERD and ulcers, reducing Cimetidine’s
a) Alcohol effectiveness. NSAIDs can increase the risk of
b) Smoking GI bleeding and should be avoided if possible.
c) NSAIDs
d) All of the above
2/35
,8/17/25, 10:19
AM
Which of the following a) Hepatotoxicity
complications should a Rationale: Cimetidine can cause liver
nurse monitor for in a damage, so patients should be monitored for
patient taking jaundice and elevated liver enzymes.
Cimetidine?
a) Hepatotoxicity
b) Hypertension
c) Hypoglycemia
d) Bradycardia
Cimetidine inhibits the c) It can increase the levels of drugs metabolized by
CYP450 enzyme system CYP450
in the liver. This means: Rationale: Cimetidine inhibits CYP450, slowing
a) It enhances the the metabolism of certain drugs, which can
metabolism of other lead to increased serum drug levels and
drugs potential toxicity.
b) It has no effect on other
drugs
c) It can increase the
levels of drugs
metabolized by
CYP450
d) It decreases the
effectiveness of all
medications
Which of the following d) All of the above
symptoms may indicate Rationale: Jaundice suggests hepatotoxicity,
a serious adverse headaches can be a side effect, and
effect of confusion/agitation may occur, especially in elderly
3/35
, 8/17/25, 10:19
AM
Cimetidine? patients.
a) Jaundice
b) Persistent headache
c) Agitation and confusion
d) All of the above
Fill in the blanks at bedtime
Cimetidine should be Rationale: Nighttime is when gastric acid
taken____________to secretion is highest, so taking Cimetidine at
maximize its bedtime helps suppress acid production
effectiveness in reducing overnight.
gastric acid secretion.
Fill in the blanks Cuts down
To help remember the Rationale: This phrase helps recall that
function of Cimetidine, a Cimetidine reduces stomach acid secretion,
useful trick is: "Cimetidine making it effective in GERD and ulcer
___stomach acid." treatment.
True or False False
Omeprazole works by Rationale: Omeprazole is a proton pump inhibitor (PPI)
blocking H2 that blocks the
receptors in the stomach hydrogen/potassium ATPase enzyme system in
to reduce acid gastric parietal cells, stopping acid production.
production. H2 blockers (like Cimetidine) work
differently.
True or False True
Omeprazole should be Rationale: PPIs work best when taken first thing
taken in the morning in the morning before meals because they
on an empty stomach inhibit active proton pumps, which are most
for maximum active in response to food.
4/35
AM
NURS 306 PHARMACOLOGY ALE 5 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED LATEST UPDATE GRADED A+
+ 2025/2026
Terms in this set (137)
True or False False
Cimetidine works by Rationale: Cimetidine is an H2 receptor
blocking H1 blocker that reduces gastric acid secretion. It
does not affect H1 receptors, which are
receptors to reduce
targeted by antihistamines for allergic
allergic reactions.
conditions.
True or False False
Cimetidine should be Rationale: Cimetidine is best taken at bedtime,
taken in the as gastric acid secretion is highest at night. This
morning for maximum helps with ulcer healing and GERD symptom
effectiveness. relief.
True or False True
Cimetidine can cause Rationale: Long-term use of Cimetidine can
gynecomastia and interfere with androgen receptors, leading to
impotence when used side effects like gynecomastia (breast tissue
long-term. enlargement in men) and impotence.
Which of the following is b) Management of GERD and ulcers
a primary therapeutic Rationale: Cimetidine is an H2 blocker that
use of Cimetidine?
1/35
,8/17/25, 10:19
AM
a) Treatment of allergic decreases gastric acid secretion, making it
reactions useful for treating GERD, gastric ulcers, and
b) Management of GERD duodenal ulcers.
and ulcers
c) Reduction of blood
pressure
d) Relief of migraine
headaches
A patient taking d) All of the above
Cimetidine should avoid Rationale: Alcohol and smoking can worsen
which of the following? GERD and ulcers, reducing Cimetidine’s
a) Alcohol effectiveness. NSAIDs can increase the risk of
b) Smoking GI bleeding and should be avoided if possible.
c) NSAIDs
d) All of the above
2/35
,8/17/25, 10:19
AM
Which of the following a) Hepatotoxicity
complications should a Rationale: Cimetidine can cause liver
nurse monitor for in a damage, so patients should be monitored for
patient taking jaundice and elevated liver enzymes.
Cimetidine?
a) Hepatotoxicity
b) Hypertension
c) Hypoglycemia
d) Bradycardia
Cimetidine inhibits the c) It can increase the levels of drugs metabolized by
CYP450 enzyme system CYP450
in the liver. This means: Rationale: Cimetidine inhibits CYP450, slowing
a) It enhances the the metabolism of certain drugs, which can
metabolism of other lead to increased serum drug levels and
drugs potential toxicity.
b) It has no effect on other
drugs
c) It can increase the
levels of drugs
metabolized by
CYP450
d) It decreases the
effectiveness of all
medications
Which of the following d) All of the above
symptoms may indicate Rationale: Jaundice suggests hepatotoxicity,
a serious adverse headaches can be a side effect, and
effect of confusion/agitation may occur, especially in elderly
3/35
, 8/17/25, 10:19
AM
Cimetidine? patients.
a) Jaundice
b) Persistent headache
c) Agitation and confusion
d) All of the above
Fill in the blanks at bedtime
Cimetidine should be Rationale: Nighttime is when gastric acid
taken____________to secretion is highest, so taking Cimetidine at
maximize its bedtime helps suppress acid production
effectiveness in reducing overnight.
gastric acid secretion.
Fill in the blanks Cuts down
To help remember the Rationale: This phrase helps recall that
function of Cimetidine, a Cimetidine reduces stomach acid secretion,
useful trick is: "Cimetidine making it effective in GERD and ulcer
___stomach acid." treatment.
True or False False
Omeprazole works by Rationale: Omeprazole is a proton pump inhibitor (PPI)
blocking H2 that blocks the
receptors in the stomach hydrogen/potassium ATPase enzyme system in
to reduce acid gastric parietal cells, stopping acid production.
production. H2 blockers (like Cimetidine) work
differently.
True or False True
Omeprazole should be Rationale: PPIs work best when taken first thing
taken in the morning in the morning before meals because they
on an empty stomach inhibit active proton pumps, which are most
for maximum active in response to food.
4/35
