600+QUESTIONS AND CORRECT ANSWERS|LATEST UPDATE|ALREADY
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1 in 6 hospital admissions are due to which is directly linked
to
polypharmacy -
Answer-an adverse drug reaction
Antipsychotic drugs remain first-line in treatment of , even in
the elderly. -
Answer-acute psychosis
Are acetylcholinesterase inhibitors and cholinesterase inhibitors the same thing -
Answer-Yes.
At what stage of Alzheimer's disease does mild cognitive impairment develop? -
Answer-Stage 2
Mild cognitive impairment (MCI)
--cognitive deficits, typically mild
--interferes with daily life
--major risk factor for frank dementia
Normal Aging
--subtle decline in episodic memory
--no effect on daily life
--Age is the single greatest risk for cognitive decline
Before managing agitation in dementia with medications, what other things
should be considered? -
Answer-Consider and treat pain, nicotine withdrawal, medication side effects,
understimulation, overstimulation, or other illnesses/infection
Benzodiazepines also increase the risk of in older adults
-
Answer-Cognitive decline and MVA
Benzodiazepines and sedative hypnotics (including the "Z" drugs) more than
double the
risk of in older adults -
fracture
Answer- Falls and hip
Can donepezil (Aricept) and memantine (Namenda) be used to treat
moderate to severe Alzheimer's disease? -
Answer-Ues
Caution should be used in prescribing memantine (Namenda) to individuals with
severe
impairment. -
Answer-Renal
,Cholinesterase inhibitors and NMDA receptor antagonists produce a
modest improvement in memory for an average of months before they
stop working. -
Answer-3-6 months
,Delirium or Dementia? Attention and awareness more preserved -
Answer-Dementia
Delirium or Dementia? Duration: months to years -
Answer-Dementia
Delirium or Dementia? Impaired recent and immediate memory -
Answer-Delirium
Early Alzheimer dementia (AD) is often confused with what other disorder? -
Answer-Depression. The first symptoms of AD are usually mood changes
Give an example of a cholinesterase inhibitor -
Answer-Donepezil (Aricept), Galantamine (Razadyne), Rivastigmine (Exelon)
How can Schizophrenia with psychosis be differentiated from dementia? -
Answer-People with psychosis are often still oriented to person, place and time
How effective are ACH inhibitors and NMDA receptor antagonists in the treatment
of dementia? -
Answer-May slow progression and improve memory and functional ability, but does not
cure the disease
How long do cholinesterase inhibitors ta?ke to work? -
Answer-Up to 6 weeks before any improvement in memory or behavior is evident (and
months before stabilization of cognition is seen).
How long does memantine (Namenda) take to work? -
Answer-It may take months until any stabilization in the degenerative course of it is seen
How should SSRIs typically be started in older adults? -
Answer-Start at one half the minimum effective dose and may double after one week if
needed
If a benzodiazepine must be used (e.g. emergent situation in a hospital setting),
Which benzodiazepine is the drug of choice? -
Answer-Lorazepam (Ativan)
--short acting (half-life does not increase with age)
--Fewer drug interactions
--No hepatic phase 1 metabolism (which declines with age)
--No active metabolites
--Available in small doses (0.25-0.5 mg po)
--Well absorbed when given IM
If an antipsychotic was needed for a person with Lewy body dementia, which
might be chose (due to decrease risk of EPS effects)? -
, Answer-Quetiapine (Seroquel)
If a patient is experiencing acute agitation and/or psychosis to the point of
needing antipsychotic medication, which medications are options? -
Answer-SGAs: Risperidone (Risperdal), Quetiapine (Seroquel), Olanzapine (Zyprexa) or
FGAs: Haloperidol (Haldol)