and All Correct Answers.
A nursing student asks the nurse to explain the role of cyclooxygenase-2 (COX-2) and its role in
inflammation. The nurse will explain that COX-2:
a. converts arachidonic acid into a chemical mediator for inflammation.
b. directly causes vasodilation and increased capillary permeability.
c. irritates the gastric mucosa to cause gastrointestinal upset.
d. releases prostaglandins, which cause inflammation and pain in tissues - Answer a. converts
arachidonic acid into a chemical mediator for inflammation
A nursing student asks how nonsteroidal anti-inflammatory drugs (NSAIDs) work to suppress
inflammation and reduce pain. The nurse will explain that NSAIDs:
a. exert direct actions to cause relaxation of smooth muscle.
b. inhibit the enzyme cyclooxygenase that is necessary for prostaglandin synthesis.
c. interfere with neuronal pathways associated with prostaglandin action.
d. suppress prostaglandin activity by blocking tissue receptor sites. - Answer b. inhibit the
enzyme cyclooxygenase that is necessary for prostaglandin synthesis.
A patient is taking ibuprofen 400 mg every 4 hours to treat moderate arthritis pain and reports
that it is less effective than before. What action will the nurse take?
a. Counsel the patient to discuss a change in dose or changing to a prescription NSAID with the
provider.
b. Recommend adding aspirin to increase the anti-inflammatory effect.
c. Suggest asking the provider about a short course of corticosteroids.
d. Tell the patient to increase the dose to 800 mg every 4 hours. - Answer a. Counsel the
patient to discuss a change in dose or changing to a prescription NSAID with the provider.
A patient who is taking aspirin for arthritis pain asks the nurse why it also causes gastrointestinal
upset. The nurse understands that this is because aspirin:
a. increases gastrointestinal secretions.
b. increases hypersensitivity reactions.
c. inhibits both COX-1 and COX-2.
,infarction and is experiencing moderate gastrointestinal upset. The nurse will contact the
patient's
provider to discuss changing from aspirin to which of the following?
a. A COX-2 inhibitor
b. Celecoxib (Celebrex)
c. Enteric-coated aspirin
d. Ibuprofen - Answer c. Enteric-coated aspirin
The nurse is performing a health history on a patient who has arthritis. The patient
reportstinnitus. Suspecting a drug adverse effect, the nurse will ask the patient about which
medication?
a. . Aspirin (Bayer)
b. Acetaminophen (Tylenol)
c. Anakinra (Kineret)
d. Prednisone (Deltasone) - Answer a. . Aspirin (Bayer)
The nurse is teaching a patient about using high-dose aspirin to treat arthritis. Whatinformation
will the nurse include when teaching this patient?
a. "A normal serum aspirin level is between 30 and 40 mg/dL."
b. "You may need to stop taking this drug a week prior to surgery."
c. "You will need to monitor aspirin levels if you are also taking warfarin."
d. "Your stools may become dark, but this is a harmless side effect." - Answer b. "You may need
to stop taking this drug a week prior to surgery."
A patient who takes high-dose aspirin to treat rheumatoid arthritis has a serum salicylate level
of
35 mg/dL. The nurse will perform which action?
a. Assess the patient for signs of toxicity, such as tinnitus.
b. Monitor the patient for signs of Reye's syndrome.
c. Notify the provider of severe aspirin toxicity.
d. Request an order for an increased aspirin dose - Answer a. Assess the patient for signs of
toxicity, such as tinnitus.
, c. "I will need to check my blood pressure frequently."
d. "I will take the medication twice daily." - Answer b. "I should take indomethacin on an empty
stomach."
10. The nurse is caring for a postpartum woman who is refusing opioid analgesics but is rating
herpain as a 7 or 8 on a 10-point pain scale. The nurse will contact the provider to request an
order for
which analgesic medication?
a. Diclofenac sodium (Voltaren)
b. Ketoprofen (Orudis)
c. Ketorolac (Toradol)
d. Naproxen (Naprosyn) - Answer c. Ketorolac (Toradol)
A patient who has osteoarthritis with mild to moderate pain asks the nurse about taking over-
the-counter ibuprofen (Motrin). What will the nurse tell this patient?
a. "It may take several weeks to achieve maximum therapeutic effects."
b. "Unlike aspirin, there is no increased risk of bleeding with ibuprofen."
c. "Take ibuprofen twice daily for maximum analgesic benefit."
d. "Combine ibuprofen with naproxen for best effect." - Answer a. "It may take several weeks
to achieve maximum therapeutic effects."
The nurse is caring for a patient who has been taking an NSAID for 4 weeks for osteoarthritis.
The patient reports decreased pain, but the nurse notes continued swelling of the affected
joints. The
nurse will perform which action?
a. Assess the patient for drug-seeking behaviors.
b. Notify the provider that the drug is not effective.
c. Reassure the patient that swelling will decrease eventually.
d. Remind the patient that this drug is given for pain only. - Answer b. Notify the provider that
the drug is not effective.
The nurse is caring for a patient who has rheumatoid arthritis and who is receiving infliximab
(Remicade) IV every 8 weeks. Which laboratory test will the nurse anticipate that this patient