WGU D116 Unit 8 Questions and
Answers A+ Graded (2025)
A .nursing .student .asks .for .clarification .on .the .differences .between .the
.mechanisms .of .spontaneous .mutation .and .conjugation .in .acquired .resistance
.of .microbes.
Which .statement .is .correct? .- .CORRECT .ANSWER-Spontaneous .mutation .leads
.to .resistance .to .only .one .antimicrobial .agent
A .patient .receiving .a .cephalosporin .develops .a .secondary .intestinal .infection
.caused .by .Clostridium .difficile.
What .is .an .appropriate .treatment .for .this .patient? .- .CORRECT .ANSWER-
Discontinuing .the .cephalosporin .and .beginning .flagyl
A .patient .is .diagnosed .with .a .lung .infection .caused .by .Pseudomonas
.aeruginosa. .The .culture .and .sensitivity .report .shows .sensitivity .to .all
.aminoglycosides. .The .provider .knows .that .the .rate .of .resistance .to .gentamicin
.is .common .in .this .hospital.
Which .medication .should .the .provider .be .expected .to .order? .- .CORRECT
.ANSWER-Amikacin
When .resistance .to .gentamicin .and .tobramycin .is .common, .amikacin .is .the
.drug .of .choice .for .the .initial .treatment .of .aminoglycoside-sensitive .infections
A .child .with .otitis .media .has .had .three .ear .infections .in .the .past .year. .The .child
.has .just .completed .a .ten-day .course .of .amoxicillin .with .no .improvement. .The
.parent .asks .the .provider .why .this .drug .is .not .working .because .it .has .worked
.in .the .past.
What .should .the .provider .tell .the .patient? .- .CORRECT .ANSWER-"The .bacteria
.have .synthesized .penicillinase"
Beta-lactamases .are .enzymes .that .cleave .the .beta-lactam .ring .and .render .the
.PCN .inactive .(amoxicillin)
Pt .will .need .to .start .augmentin
, A .patient .who .is .taking .acetaminophen .for .pain .wants .to .know .why .it .does .not
.cause .gastrointestinal .upset .as .other .over-the-counter .pain .medications .do.
Which .property .of .acetaminophen .is .the .most .likely .explanation .for .this? .-
.CORRECT .ANSWER-It .has .minimal .effects .at .peripheral .sites .
Tylenol .central .effects .
NSAIDs .peripheral .effects
A .patient .who .has .arthritis .has .been .taking .ibuprofen .and .a .glucocorticoid
.medication. .The .patient .reports .having .tarry .stools .but .denies .gastric .pain.
Which .action .by .the .provider .is .correct? .- .CORRECT .ANSWER-Prescribing .an
.antiulcer .medication
Glucocorticoid .therapy, .especially .when .combined .with .NSAIDs, .can .increase
.the .risk .of .gastric .ulcer .and .possibly .bleeding
A .patient .will .begin .taking .hydroxychloroquine .for .rheumatoid .arthritis. .The
.patient .is .currently .taking .high-dose .NSAIDs .and .methotrexate.
What .should .the .patient .be .taught .about .hydroxychloroquine? .- .CORRECT
.ANSWER-An .eye .exam .is .necessary .at .the .beginning .of .therapy .with .this .drug
Can .cause .retinal .damage .- .eye .exam .at .the .onset .of .treatment .as .well .as .every
.6 .months .during .treatment
A .patient .with .gout .who .has .increasingly .frequent .acute .gouty .attacks .will
.begin .receiving .allopurinol .and .colchicine.
Which .statement .should .be .included .when .teaching .the .patient .about .this .drug
.regimen? .- .CORRECT .ANSWER-"You .will .take .both .drugs .initially .and .then
.stop .taking .colchicine"
Colchicine .is .used .for .prophylaxis .when .urate-lowering .drugs .(allopurinal) .are
.initiated .because .gouty .episodes .often .increase .during .this .time.
A .postmenopausal .patient .develops .osteoporosis. .The .patient .asks .the .provider
.about .medications .to .treat .this .condition. .The .provider .learns .that .the .patient
.has .a .family .history .of .breast .cancer.
Which .medication .should .the .provider .discuss .with .the .patient? .- .CORRECT
.ANSWER-Raloxifene .
Can .preserve .bone .mineral .density .while .protecting .against .breast .and
.endometrial .cancers
Which .of .the .following .antibiotics .is .in .a .class .of .drugs .known .for .ototoxicity?
.- .CORRECT .ANSWER-Gentamicin
Aminoglycoside .abx .which .as .a .class .are .known .to .cause .ototoxicity
Answers A+ Graded (2025)
A .nursing .student .asks .for .clarification .on .the .differences .between .the
.mechanisms .of .spontaneous .mutation .and .conjugation .in .acquired .resistance
.of .microbes.
Which .statement .is .correct? .- .CORRECT .ANSWER-Spontaneous .mutation .leads
.to .resistance .to .only .one .antimicrobial .agent
A .patient .receiving .a .cephalosporin .develops .a .secondary .intestinal .infection
.caused .by .Clostridium .difficile.
What .is .an .appropriate .treatment .for .this .patient? .- .CORRECT .ANSWER-
Discontinuing .the .cephalosporin .and .beginning .flagyl
A .patient .is .diagnosed .with .a .lung .infection .caused .by .Pseudomonas
.aeruginosa. .The .culture .and .sensitivity .report .shows .sensitivity .to .all
.aminoglycosides. .The .provider .knows .that .the .rate .of .resistance .to .gentamicin
.is .common .in .this .hospital.
Which .medication .should .the .provider .be .expected .to .order? .- .CORRECT
.ANSWER-Amikacin
When .resistance .to .gentamicin .and .tobramycin .is .common, .amikacin .is .the
.drug .of .choice .for .the .initial .treatment .of .aminoglycoside-sensitive .infections
A .child .with .otitis .media .has .had .three .ear .infections .in .the .past .year. .The .child
.has .just .completed .a .ten-day .course .of .amoxicillin .with .no .improvement. .The
.parent .asks .the .provider .why .this .drug .is .not .working .because .it .has .worked
.in .the .past.
What .should .the .provider .tell .the .patient? .- .CORRECT .ANSWER-"The .bacteria
.have .synthesized .penicillinase"
Beta-lactamases .are .enzymes .that .cleave .the .beta-lactam .ring .and .render .the
.PCN .inactive .(amoxicillin)
Pt .will .need .to .start .augmentin
, A .patient .who .is .taking .acetaminophen .for .pain .wants .to .know .why .it .does .not
.cause .gastrointestinal .upset .as .other .over-the-counter .pain .medications .do.
Which .property .of .acetaminophen .is .the .most .likely .explanation .for .this? .-
.CORRECT .ANSWER-It .has .minimal .effects .at .peripheral .sites .
Tylenol .central .effects .
NSAIDs .peripheral .effects
A .patient .who .has .arthritis .has .been .taking .ibuprofen .and .a .glucocorticoid
.medication. .The .patient .reports .having .tarry .stools .but .denies .gastric .pain.
Which .action .by .the .provider .is .correct? .- .CORRECT .ANSWER-Prescribing .an
.antiulcer .medication
Glucocorticoid .therapy, .especially .when .combined .with .NSAIDs, .can .increase
.the .risk .of .gastric .ulcer .and .possibly .bleeding
A .patient .will .begin .taking .hydroxychloroquine .for .rheumatoid .arthritis. .The
.patient .is .currently .taking .high-dose .NSAIDs .and .methotrexate.
What .should .the .patient .be .taught .about .hydroxychloroquine? .- .CORRECT
.ANSWER-An .eye .exam .is .necessary .at .the .beginning .of .therapy .with .this .drug
Can .cause .retinal .damage .- .eye .exam .at .the .onset .of .treatment .as .well .as .every
.6 .months .during .treatment
A .patient .with .gout .who .has .increasingly .frequent .acute .gouty .attacks .will
.begin .receiving .allopurinol .and .colchicine.
Which .statement .should .be .included .when .teaching .the .patient .about .this .drug
.regimen? .- .CORRECT .ANSWER-"You .will .take .both .drugs .initially .and .then
.stop .taking .colchicine"
Colchicine .is .used .for .prophylaxis .when .urate-lowering .drugs .(allopurinal) .are
.initiated .because .gouty .episodes .often .increase .during .this .time.
A .postmenopausal .patient .develops .osteoporosis. .The .patient .asks .the .provider
.about .medications .to .treat .this .condition. .The .provider .learns .that .the .patient
.has .a .family .history .of .breast .cancer.
Which .medication .should .the .provider .discuss .with .the .patient? .- .CORRECT
.ANSWER-Raloxifene .
Can .preserve .bone .mineral .density .while .protecting .against .breast .and
.endometrial .cancers
Which .of .the .following .antibiotics .is .in .a .class .of .drugs .known .for .ototoxicity?
.- .CORRECT .ANSWER-Gentamicin
Aminoglycoside .abx .which .as .a .class .are .known .to .cause .ototoxicity
