8/21/25, 8:30
AM
N301 PHARM MIDTERM EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE GRADED A 2025
Terms in this set (193)
1) Absorption
What are the 4 basic 2) Distrib
pharmacokinetic ution
processes? 3)Meta
bolism
4) Excretion
What is absorption? Drug moves from its site of administration into the
venous or lymphatic circulation
What is distribution? the delivery of the drug into any and all body
compartments it can penetrate
i. Regional blood flow and capillary permeability
ii. Ability of a drug to exit the vascular system (more
water soluble)
iii. Ability of a drug to enter cells (more lipid soluble)
What are factors that iv. Physiologic barriers
influence distribution? v. The volume of distribution
vi. Cardiac output
vii. Degree of plasma protein binding
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, 8/21/25, 8:30
AM
viii. Drug reservoirs or storage sites
ix. Drug concentration tissue affinity
What is metabolism? also known as biotransformation enzymatically
medicated alteration of drug structure
What is metabolites? The alteration or changing of a drug to more
ionized or water-soluble and less lipid- soluble
forms metabolites.
What is the primary Liver
organ of metabolism?
What is excretion? movement of drugs and their metabolites out of the
body
Metabolism + Excretion = elimination
What does drug Hepatic Metabolism
elimination begin with?
What is hepatic Renal excretion
metabolism followed by?
2/
14
AM
N301 PHARM MIDTERM EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE GRADED A 2025
Terms in this set (193)
1) Absorption
What are the 4 basic 2) Distrib
pharmacokinetic ution
processes? 3)Meta
bolism
4) Excretion
What is absorption? Drug moves from its site of administration into the
venous or lymphatic circulation
What is distribution? the delivery of the drug into any and all body
compartments it can penetrate
i. Regional blood flow and capillary permeability
ii. Ability of a drug to exit the vascular system (more
water soluble)
iii. Ability of a drug to enter cells (more lipid soluble)
What are factors that iv. Physiologic barriers
influence distribution? v. The volume of distribution
vi. Cardiac output
vii. Degree of plasma protein binding
1/
14
, 8/21/25, 8:30
AM
viii. Drug reservoirs or storage sites
ix. Drug concentration tissue affinity
What is metabolism? also known as biotransformation enzymatically
medicated alteration of drug structure
What is metabolites? The alteration or changing of a drug to more
ionized or water-soluble and less lipid- soluble
forms metabolites.
What is the primary Liver
organ of metabolism?
What is excretion? movement of drugs and their metabolites out of the
body
Metabolism + Excretion = elimination
What does drug Hepatic Metabolism
elimination begin with?
What is hepatic Renal excretion
metabolism followed by?
2/
14
