8/21/25, 8:30
AM
N301 PHARMACOLOGY DREXEL ACE EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED UPDATE 2025/2026
Terms in this set (46)
What is pharmacokinetics? study of drug movement through the body
What are the 4 elements absorption, distribution, metabolism, excretion
of Pharmacokinetics?
What are the 3 ways a through channels or pores, aided by a transport
drug can cross a system, direct penetration of membrane
membrane?
What 6 things effect Rate kid dissolution, surface area, blood flow, lipid
absorption solubility, pH partioning, route of administration
What is absorption Movement of the drug from the site of administration
into the blood
Advantages of IV Rapid onset, control of level of drug, ability to
administration? administer large volumes of fluid
What is enteral Using GI tract
absorption?
Advantages of IM Good for mess with poor water solubility, used for
administration? depot administrations
Advantages of oral route? Easy, convenient, safe
Disadvantages of oral Variability of absorption
route?
1/
6
, 8/21/25, 8:30
AM
What is chemical Contains some amount of an identical compound
equivalence?
What is bioavailability? 2 drugs are equal in bioavailability if they are absorbed
at same rate
What is distribution? Movement of drugs throughout the body
What 3 factors effect Blood flow, ability to exit the vascular system, ability of
distribution? the drug to enter the cells
What 2 pathologic Abscesses and solid tumors
conditions create low
blood flow that affects
drug distribution?
What 3 ways can Blood brain barrier, placenta, protein binding
drugs exit the
vascular system?
What is drug related The enzymatic alteration of drug structure
metabolism?
Where does most The liver
metabolism take place?
What hepatic enzyme Cytochrome P450
metabolizes drugs?
What are the 5 Accelerated renal excretion, drug inactivation,
therapeutic increased therapeutic action, activation of
consequences of drug prodrugs, changes in toxicity.
metabolism?
What is "first pass effect?" Rapid inactivation of some oral drugs as they
pass through the liver. Little drug is left to
work. Parenteral admin bypasses this effect
What is parenteral Outside of GI tract, IV, IM, subQ
absorption and the 3
2/
6
AM
N301 PHARMACOLOGY DREXEL ACE EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED UPDATE 2025/2026
Terms in this set (46)
What is pharmacokinetics? study of drug movement through the body
What are the 4 elements absorption, distribution, metabolism, excretion
of Pharmacokinetics?
What are the 3 ways a through channels or pores, aided by a transport
drug can cross a system, direct penetration of membrane
membrane?
What 6 things effect Rate kid dissolution, surface area, blood flow, lipid
absorption solubility, pH partioning, route of administration
What is absorption Movement of the drug from the site of administration
into the blood
Advantages of IV Rapid onset, control of level of drug, ability to
administration? administer large volumes of fluid
What is enteral Using GI tract
absorption?
Advantages of IM Good for mess with poor water solubility, used for
administration? depot administrations
Advantages of oral route? Easy, convenient, safe
Disadvantages of oral Variability of absorption
route?
1/
6
, 8/21/25, 8:30
AM
What is chemical Contains some amount of an identical compound
equivalence?
What is bioavailability? 2 drugs are equal in bioavailability if they are absorbed
at same rate
What is distribution? Movement of drugs throughout the body
What 3 factors effect Blood flow, ability to exit the vascular system, ability of
distribution? the drug to enter the cells
What 2 pathologic Abscesses and solid tumors
conditions create low
blood flow that affects
drug distribution?
What 3 ways can Blood brain barrier, placenta, protein binding
drugs exit the
vascular system?
What is drug related The enzymatic alteration of drug structure
metabolism?
Where does most The liver
metabolism take place?
What hepatic enzyme Cytochrome P450
metabolizes drugs?
What are the 5 Accelerated renal excretion, drug inactivation,
therapeutic increased therapeutic action, activation of
consequences of drug prodrugs, changes in toxicity.
metabolism?
What is "first pass effect?" Rapid inactivation of some oral drugs as they
pass through the liver. Little drug is left to
work. Parenteral admin bypasses this effect
What is parenteral Outside of GI tract, IV, IM, subQ
absorption and the 3
2/
6
