Questions with Correct Detailed
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1. the three classes of opioid receptors - ANSWER ✓ mu, kappa, delta
2. the three endogenous opioid peptides - ANSWER ✓ endorphins,
enkephalins, dynorphins
3. morphine toxicity - "classic triad" of signs - ANSWER ✓ coma, respiratory
depression, miosis
4. morphine overdose antidote - ANSWER ✓ naloxone (Narcan)
5. effect of morphine interaction with anticholinergic drugs (including
antihistamines such as diphenhydramine (Benadryl)) - ANSWER ✓
exacerbate constipation and urinary retention
6. which drug is 100x more potent than morphine (it is another pure opioid
agonist)? - ANSWER ✓ fentanyl
7. three examples of moderate to strong opioid agonists - ANSWER ✓ codeine,
oxycodone, hydrocodone
8. what is the most widely prescribed drug in the US? - ANSWER ✓
hydrocodone
, 9. what happens when buprenorphine is given to an opioid-dependent client? -
ANSWER ✓ buprenorphine produces less opiate effects; precipitated
withdrawal can occur
10.clients can build a tolerance to all opioid adverse effects with the exception
of ___________ and ____________ - ANSWER ✓ constipation, miosis
11.consequence of placing a heating pad over a fentanyl (Duragesic)
transdermal patch - ANSWER ✓ can cause acceleration in release of drug
which could increase the drug levels causing toxicity
12.miosis - ANSWER ✓ pinpoint pupils
13.patient-controlled analgesia (PCA) - ANSWER ✓ a method of drug delivery
that permits the patient to self-administer parenteral opioids on an "as-
needed" basis
14.opioid - ANSWER ✓ any drug, natural or synthetic, that has actions similar
to those of morphine
15.analgesics - ANSWER ✓ drugs that relieve pain without causing loss of
consciousness
16.opioid mechanism of action - ANSWER ✓ bind to receptors in the CNS and
spinal cord to produce an altered perception to pain (reduction in pain
sensation)
17.which of the following receptors is most important when it comes to pain
relief?
18.-mu, kappa, or delta? - ANSWER ✓ mu receptors
19.adjuvant analgesic drugs - ANSWER ✓ drugs that are added for combined
therapy with a primary drug and may have additive or independent analgesic
properties, or both.
20.do opioid drugs bind to delta receptors? - ANSWER ✓ no